T c osborn (16 Ergebnisse)

Zustand: Very Good. Item in very good condition! Textbooks may not include supplemental items i.e. CDs, access codes etc.

Mass Market Paperback. Zustand: Good. No Jacket. Pages can have notes/highlighting. Spine may show signs of wear. ~ ThriftBooks: Read More, Spend Less.

Mass Market Paperback. Zustand: Good. No Jacket. Pages can have notes/highlighting. Spine may show signs of wear. ~ ThriftBooks: Read More, Spend Less.

Paperback. Zustand: Fair. No Jacket. Readable copy. Pages may have considerable notes/highlighting. ~ ThriftBooks: Read More, Spend Less.

No Binding. Zustand: Very Good. ORIGINAL article, disbound from journal; no covers; in very good condition. Book.

No Binding. Zustand: Very Good. ORIGINAL article, disbound from journal; no covers; in very good condition. Book.

Soft cover. Zustand: Very Good. 1st Edition. RARE. SC - Stable-bound. Green wraps with blank font face. Originally priced .50, stamped on front cover. Small stains on front/rear wraps (see pics). Clean Interior. No markings. 4to. i/ii + 43pp including a selected Bibliography with Notations. --B.R. Box 114. …

Zustand: Fair. This is an ex-library book and may have the usual library/used-book markings inside.This book has soft covers. Clean from markings. In fair condition, suitable as a study copy. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,500grams, ISBN:1880028026.…

Zustand: New. In English.

Paperback. Zustand: Brand New. 250 pages. 9.45x6.30x0.61 inches. In Stock.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - JACQUES S. BECKMANN & THOMAS C. OSBORN Extraordinary progress has been made in the analyses of the genetic structures of higher eukaryotic genomes. Only ten years elapsed between the initial proposals to use molecular DNA markers for the generation of a complete linkage map of the human genome [5, 17] and the first description of a 10 centimorgan map of one of its chromosomes [22], soon to be followed by others. The availability of molecular DNA markers, henceforth called genomic markers [for a review of their properties see 1, 2, 20], represents a milestone in genetics by providing the capacity for complete genetic coverage of all genomes. It is important to remember that the nature of the DNA polymorphism or of the specific method used to uncover it can be quite different for different marker loci. The genetic variation detected can be a result of a simple point mutation, a DNA insertion/deletion event, or a change in repeat copy number at some hypervariable DNA [11] or micro satellite [21] motif. Currently, the methods of detection can involve use of restriction endonucleases, nucleic acid hybridization, or DNA sequence amplification. Each of these sources of var iation and methods of detection can have utility for different applications. Furthermore, new approaches for the detection of DNA polymorphism are constantly emerging. The primary concern here is that the monitored poly morphism defines a genetic marker 'useful' for the desired application.…

Zustand: New. In English.

Gebunden. Zustand: New. The main application of genomic markers is the mapping, diagnosis, understanding, manipulation and eventual molecular cloning of loci of medical, biologic or economic interest. These achievements are likely to have a practical impact not only in basic scien.

Hardcover. Zustand: Brand New. 268 pages. 9.75x6.75x0.75 inches. In Stock.

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The main application of genomic markers is the mapping, diagnosis, understanding, manipulation and eventual molecular cloning of loci of medical, biologic or economic interest. These achievements are likely to have a practical impact not only in basic science, e.g. in the elucidation of the basic processes involved in a particular pathway or in retracing the history of plant speciation, but also in breeding practice. In agriculture this translates into the exploitation of this knowledge for further genetic improvement since traits of agronomic interest are often polygenic. The elucidation of the genetic basis of polygenic inheritance and the subsequent efficient utilization of this knowledge in breeding schemes require the availability of an adequate network of genetic markers spanning the entire genome. The purpose of the present manual is to provide new investigators in this area with an introduction and a basic practical state-of-the-art description of how to proceed.…

Wraps. Zustand: Good. Presumed First Printing. iv, 25 pages plus four sheets of charts. Footnotes. Part one contains Abstract, Summary, Administrative Information, Methods, Table, and Figures. Part two contains tables, graphs, summary. references. Marked "Internal Use Only Not For External Distribution" Unclassified. Cover has stamps and markings. Donald J. Kimeldorf stamped on front cover--this was one of the author's copy. Stamp on page 1 also. Part 1 of this report describes a series of experiments in which partial-body exposure to doses of X rays from 200 to 500 r was used to study the previously reported X irradiation. In the study summarized in Part 2 of this report, post-irradiation administration of homologous bone marrow suspension was employed to test the hypothesis that the decrease in volitional activity performed during the 2nd and 3rd weeks related to a hematopoietic deficiency. It appears that hematopoietic injury is the mediating process involved in this performance decrement.…