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Zustand: New. In.

Gr. 8°, Hardcover. Zustand: Sehr gut. Ill., 251 S. Sprache: Englisch; sehr gutes Ex. Sprache: Englisch Gewicht in Gramm: 730.

Zustand: New. In.

Gebunden. Zustand: New.

Kartoniert / Broschiert. Zustand: New.

Taschenbuch. Zustand: Neu. Proton Pump Inhibitors | Lars Olbe | Taschenbuch | x | Englisch | 2013 | Birkhäuser | EAN 9783034897778 | Verantwortliche Person für die EU: Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Inhibition of the proton pump in the parietal cells has been established as the main therapeutic principle in the treatment of acid-related diseases, such as peptic ulcer and gastro-oesophageal reflux. The proton pump inhi bitors are tailored for their purpose. They accumulate in the target cell, are activated by acid and bind strongly to the specific target - the proton pump. The clinical superiority of the proton pump inhibitors is due not only to their high efficacy but also to the long duration of the acid inhibition in comparison with other antisecretory drugs. At present when drug discovery mostly relies on identification and characterization of potential targets by genome research, molecular biology, combinatorial chemistry and automated screening, it seems worthwhile to present the development of the tITst proton pump inhibitor - omeprazol- starting from a chemical structure with an observed antisecretory effect but also severe toxic effects that had to be eliminated. As always, basic and applied research operate luind in hand to optimize the delicate balance be tween efficacy and safety of a new drug. This goal often involves time and many different specialists.

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Inhibition of the proton pump in the parietal cells has been established as the main therapeutic principle in the treatment of acid-related diseases, such as peptic ulcer and gastro-oesophageal reflux. The proton pump inhi bitors are tailored for their purpose. They accumulate in the target cell, are activated by acid and bind strongly to the specific target - the proton pump. The clinical superiority of the proton pump inhibitors is due not only to their high efficacy but also to the long duration of the acid inhibition in comparison with other antisecretory drugs. At present when drug discovery mostly relies on identification and characterization of potential targets by genome research, molecular biology, combinatorial chemistry and automated screening, it seems worthwhile to present the development of the tITst proton pump inhibitor - omeprazol- starting from a chemical structure with an observed antisecretory effect but also severe toxic effects that had to be eliminated. As always, basic and applied research operate luind in hand to optimize the delicate balance be tween efficacy and safety of a new drug. This goal often involves time and many different specialists.

Paperback. Zustand: Brand New. 1999 edition. 268 pages. 9.60x6.69x0.61 inches. In Stock.

Zustand: New. Editor(s): Olbe, Lars. Series: Milestones in Drug Therapy. Num Pages: 261 pages, biography. BIC Classification: MB. Category: (P) Professional & Vocational. Dimension: 244 x 170 x 14. Weight in Grams: 467. . 2013. 1999th Edition. paperback. . . . . Books ship from the US and Ireland.

Zustand: New. This monograph contains a description of the discovery and development of a new antisecretory therapy in the treatment of acid-related diseases: omeprazole, the first pump inhibitor. The pharmacology of different proton pump inhibitors and the pharmaceutic delivery system are reviewed. Editor(s): Olbe, Lars. Series: Milestones in Drug Therapy. Num Pages: 261 pages, biography. BIC Classification: MJH; MMG. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly. Dimension: 244 x 170 x 20. Weight in Grams: 730. . 1999. Hardback. . . . . Books ship from the US and Ireland.