lange robert c (21 Ergebnisse)

Hardcover/Pappeinband. Zustand: Sehr gut. 228 p. Very good. Shrink wrapped. / Sehr guter Zustand. In Folie verschweißt. Sprache: Englisch Gewicht in Gramm: 550.

Wraps. Zustand: Fair. Pages 887-897, [1] pages. Tables. References. Hole through several pages. Stamp and ink notations on front page. During the medical surveys of adult atomic bomb survivors carried out in the Atomic Bomb Casualty Commission Clinic in Hiroshima, nine cased of leukemia were encountered. An account of these cases is presented in this report. William Curry Moloney, MD, who studied and treated blood diseases before hematology became a medical specialty, was a professor emeritus of medicine at Harvard Medical School and former director of hematology at Brigham and Women's Hospital. He was one of the first hematologists to use chemotherapy to treat leukemia and lymphoma. Dr. Moloney was also an early contributor to the development of specific diagnostic tests, some of which are still in use today. Dr. Moloney was a recognized authority on safe procedures for blood transfusions, and his expertise in blood banks stood him in good stead in World War II, when he oversaw transfusions to wounded soldiers. After the war, in the early 1950s, Dr. Moloney directed research for the Atomic Bomb Casualty Commission in Hiroshima, Japan. Later, in the Marshall Islands, he studied the effects of errant radiation and the mechanisms that produce leukemia. Robert Dale Lange received a BS from Macalester College at St. Paul, Minn., in 1941, and an M. D. from Washington University's School of Medicine at St. Louis, Missouri, in 1944. He was a major in the U. S. Army and served on the Atomic Bomb Casualty Commission at Hiroshima from 1951-1953. In 1964, Lange to Knoxville, Tennessee, to work for the University of Tennessee Memorial Research Center and Hospital (UTMRCH), where he rose to the rank of director. Lange became professor and chairman in the Department of Medical Biology by 1978. From 1969 to 1993 as a representative of UT, he acted as a member of their Human Subjects Committee. In 1985, Dr. Lange retired; but as a professor emeritus and practicing doctor, he continued his work in hematology. As investigator on several NASA experiments, he enabled UT's medical projects fly on the space shuttles in the late 1980s and early 1990s, including Challenger's ill-fated mission of 1986. Lange's professional career also includes over 150 journal papers and book chapters, as well as a tremendous number of reviews and abstracts. He was a Fellow of the American College of Physicians and of the International Society of Hematology and a member of many national and international societies and organizations, including Sigma XI and Pi Phi Epsilon. Reprinted from Texas Reports on Biology and Medicine, Volume 12, Number 4, pages 887-897, Winter 1954.

Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Zustand: Used. pp. 240.

Zustand: New. In.

Zustand: New. In.

Zustand: New. In.

Taschenbuch. Zustand: Neu. Drug Delivery to the Brain | Physiological Concepts, Methodologies and Approaches | Margareta Hammarlund-Udenaes (u. a.) | Taschenbuch | xx | Englisch | 2016 | Springer US | EAN 9781493943661 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.

Taschenbuch. Zustand: Neu. Drug Delivery to the Brain | Physiological Concepts, Methodologies and Approaches | Elizabeth C. M. De Lange (u. a.) | Taschenbuch | AAPS Advances in the Pharmaceutical Sciences Series | xxi | Englisch | 2023 | Springer | EAN 9783030887759 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.

Zustand: Sehr gut. Zustand: Sehr gut | Seiten: 828 | Sprache: Englisch | Produktart: Bücher | The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the blood¿brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/passive transport across the BBB, intra-brain distribution, and central/systemic pharmacokinetics, to name a few. Neurological disease and trauma conditions add further complexity because CNS barriers, drug distribution and pharmacokinetics are dynamic and often changed by disease/trauma. Knowledge of all these factors and their interplay in different conditions is of utmost importance for proper CNS drug development and disease treatment. In recent years much information has become available for a better understanding of the many factors important for CNS drug delivery and how they interact to affect drug action. This book describes small and large drug delivery to the brain with anemphasis on the physiology of the BBB and the principles and concepts for drug delivery across the BBB and distribution within the brain. It contains methods descriptions for studying drug delivery, routes and approaches of administering drugs into the brain, the influence of disease, drug industry perspectives, and a primer on neuroanatomy and physiological considerations written specifically for drug delivery scientists. Therewith, it contributes to an in-depth understanding of the interplay between brain (patho)-physiology and drug characteristics. Furthermore, the content is designed to be both cutting-edge and educational, so that the book can be used in high-level training of academic and industry scientists with full references to original publications.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the blood -brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/passive transport across the BBB, intra-brain distribution, and central/systemic pharmacokinetics, to name a few. Neurological disease and trauma conditions add further complexity because CNS barriers, drug distribution and pharmacokinetics are dynamic and often changed by disease/trauma. Knowledge of all these factors and their interplay in different conditions is of utmost importance for proper CNS drug development and disease treatment. In recent years much information has become available for a better understanding of the many factors important for CNS drug delivery and how they interact to affect drug action. This book describes small and large drug delivery to the brain with an emphasis on the physiology of the BBB and the principles and concepts for drug delivery across the BBB and distribution within the brain. It contains methods descriptions for studying drug delivery, routes and approaches of administering drugs into the brain, the influence of disease, and drug industry perspectives. Therewith, it contributes to an in-depth understanding of the interplay between brain (patho)-physiology and drug characteristics. Furthermore, the content is designed to be both cutting-edge and educational, so that the book can be used in high-level training of academic and industry scientists with full references to original publications.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the blood-brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/passive transport across the BBB, intra-brain distribution, and central/systemic pharmacokinetics, to name a few.Neurological disease and trauma conditions add further complexity because CNS barriers, drug distribution and pharmacokinetics are dynamic and often changed by disease/trauma. Knowledge of all these factors and their interplay in different conditions is of utmost importance for proper CNS drug development and disease treatment. In recent years much information has become available for a better understanding ofthe many factors important for CNS drug delivery and how they interact to affect drug action. This book describes small and large drug delivery to the brain with anemphasis on the physiology of the BBB and the principles and concepts for drug delivery across the BBB and distribution within the brain. It contains methods descriptions for studying drug delivery, routes and approaches of administering drugs into the brain, the influence of disease, drug industry perspectives, and a primer on neuroanatomy and physiologicalconsiderations writtenspecifically for drug delivery scientists. Therewith, it contributes to an in-depth understanding of the interplay between brain (patho)-physiology and drug characteristics. Furthermore, the content is designed to be both cutting-edge and educational, so that the book can be used in high-level training of academic and industry scientists with full references to original publications.

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the blood-brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/passive transport across the BBB, intra-brain distribution, and central/systemic pharmacokinetics, to name a few.Neurological disease and trauma conditions add further complexity because CNS barriers, drug distribution and pharmacokinetics are dynamic and often changed by disease/trauma. Knowledge of all these factors and their interplay in different conditions is of utmost importance for proper CNS drug development and disease treatment. In recent years much information has become available for a better understanding ofthe many factors important for CNS drug delivery and how they interact to affect drug action. This book describes small and large drug delivery to the brain with anemphasis on the physiology of the BBB and the principles and concepts for drug delivery across the BBB and distribution within the brain. It contains methods descriptions for studying drug delivery, routes and approaches of administering drugs into the brain, the influence of disease, drug industry perspectives, and a primer on neuroanatomy and physiologicalconsiderations writtenspecifically for drug delivery scientists. Therewith, it contributes to an in-depth understanding of the interplay between brain (patho)-physiology and drug characteristics. Furthermore, the content is designed to be both cutting-edge and educational, so that the book can be used in high-level training of academic and industry scientists with full references to original publications.

Paperback. Zustand: New. &Uumlber den AutorRaji C. Steineck, Ph.D. (1999), Bonn University, is Professor of Japanology at the University of Zurich. He has published extensively on Japanese intellectual history and philosophy and pursues a long-term project on t.

Paperback. Zustand: Brand New. 2nd edition. 827 pages. 9.25x6.10x1.65 inches. In Stock.

Taschenbuch. Zustand: Neu. Neuware - The contributions to Concepts of Philosophy in Asia and the Islamic World reflect upon the problems implied in the received notions of philosophy in the respective scholarly literatures. They ask whether, and for what reasons, a text should be categorized as a philosophical text (or excluded from the canon of philosophy), and what this means for the concept of philosophy. The focus on texts and textual corpora is central because it makes authors expose their claims and arguments in direct relation to specific sources, and discourages generalized reflections on the characteristics of, for example, Japanese culture or the Indian mind. The volume demonstrates that close and historically informed readings are the sine qua non in discussing what philosophy is in Asia and the Islamic world, just as much as with regard to Western literatureContributors are Yoko Arisaka, Wolfgang Behr, Thomas Fröhlich, Lisa Indraccolo, Paulus Kaufmann, Iso Kern, Ralf Müller, Gregor Paul, Lisa Raphals, Fabian Schäfer, Ori Sela, Rafael Suter, Christian Uhl, Viatcheslav Vetrov, Yvonne Schulz Zinda, and Nicholas Zufferey.

Hardcover. Zustand: Sehr gut. Zustand des Schutzumschlags: Sehr gut. 1. Auflage. Z : 376 Seiten, 395 Abb. Leinen mit Schutzumschlag - Neben großformatigen, ganzseitigen Reproduktionen der Kunstwerke bietet das Buch eine Chronologie des Hauses und eine Vielzahl von begleitenden, erläuternden Texten führender Kunsthistoriker, die teilweise erstmals in deutscher Sprache vorgelegt wurden.

Wraps. Zustand: Good. Pages 663-685, [1]. Figures. Tables. References. Contains a Summary section in Spanish following the English text. The name Donald J. Kimeldorf stamped on front page. Initials RW written on front page. A total of seventy-five cases of leukemia occurring in survivors have been investigated by the Atomic Bomb Casualty Commissions and ten of these ere encountered during then course of medical and hematological surveys. Observations on some of these patients have afforded a unique opportunity to study the early hematological and preclinical phases of leukemia in atomic bomb survivors and the results of these investigations are reported in this paper. One of the summary items was that certain features of chronic myelogenous leukemia following irradiation suggested that the disorder might be due to a loss of growth-promoting or regulating factors. Blood is a peer-reviewed medical journal published by the American Society of Hematology. It was established by William Dameshek in 1946. It covers clinical and basic research in all areas of hematology, including disorders of leukocytes, both benign and malignant, erythrocytes, platelets, hemostatic mechanisms, vascular biology, immunology, and hematological oncology. Kimeldorf was a major scientific leader. His book with Ed Hunt entitled "Ionizing radiation: Neural function and behavior" is a thorough description of the physiological and behavioral effects of exposure to ionizing radiation. William Curry Moloney, MD, who studied and treated blood diseases before hematology became a medical specialty, was a professor emeritus of medicine at Harvard Medical School and former director of hematology at Brigham and Women's Hospital. He was one of the first hematologists to use chemotherapy to treat leukemia and lymphoma. Dr. Moloney was also an early contributor to the development of specific diagnostic tests, some of which are still in use today. Dr. Moloney was a recognized authority on safe procedures for blood transfusions, and his expertise in blood banks stood him in good stead in World War II, when he oversaw transfusions to wounded soldiers. After the war, in the early 1950s, Dr. Moloney directed research for the Atomic Bomb Casualty Commission in Hiroshima, Japan. Later, in the Marshall Islands, he studied the effects of errant radiation and the mechanisms that produce leukemia. Born in Minnesota on January 24, 1920, Robert Dale Lange received a BS from Macalester College at St. Paul, Minn., in 1941, and an M. D. from Washington University's School of Medicine at St. Louis, Missouri, in 1944. He was a major in the U. S. Army and served on the Atomic Bomb Casualty Commission at Hiroshima from 1951-1953. In 1964, Lange to Knoxville, Tennessee, to work for the University of Tennessee Memorial Research Center and Hospital (UTMRCH), where he rose to the rank of director. Lange became professor and chairman in the Department of Medical Biology by 1978. From 1969 to 1993 as a representative of UT, he acted as a member of their Human Subjects Committee. In 1985, Dr. Lange retired; but as a professor emeritus and practicing doctor, he continued his work in hematology. As investigator on several NASA experiments, he enabled UT's medical projects fly on the space shuttles in the late 1980s and early 1990s, including Challenger's ill-fated mission of 1986. Lange's professional career also includes over 150 journal papers and book chapters, as well as a tremendous number of reviews and abstracts. He was a Fellow of the American College of Physicians and of the International Society of Hematology and a member of many national and international societies and organizations, including Sigma XI and Pi Phi Epsilon. Reprinted from Blood: The Journal of Hematology, Vol. IX, No. Y, July 1954.

Hardcover. Zustand: Sehr gut. 1. Auflage. Z/W : 352 Seiten, 17 x 22 cm, 182 farbige und s/w Abbildungen - Dieses einzigartige Buch, das in Zusammenarbeit mit den Künstlern entwickelt wurde, begleitet eine große, retrospektive Wanderausstellung und ist die umfangreichste visuelle Aufzeichnung ihres außergewöhnlich vielfältigen Werks, das bisher veröffentlicht wurde. Zu den vorgestellten Autoren gehören Kritiker, Kuratoren, Kulturkommentatoren, Künstler und Filmemacher, die eine Vielzahl von Stimmen in eine Karriere einbringen, die sich ebenso leicht über Grenzen hinwegsetzt wie sich einer einfachen Klassifizierung entzieht.

24 unnumbered pages on medium-glossy paper, mainly photographically - partly wholepage - illustrated throughout (''Die Original-Aufnahmen sind mit gütiger Erlaubnis des Kommandanten, Major S.R. Sands, hergestellt''). - Grey-brown original illustrated cardboard-cover (decent art-nouveau design: Richard Kunze), stapled; oblong-4to.(ca. 22 x 29 cm). *** [ERWEITERTER SOMMERVERKAUF / EXPANDED SUMMER-SALE: um über 30% REDUZIERTER PREIS bis Montag, den 20.07.2026 / PRICE-REDUCTION of over 30% until Monday, July 20; ursprünglicher Preis / originally EUR 480,-] --- 1. AUFLAGE, GRÖSSERFORMATIGE BROSCHIERTE ORIGINALAUSGABE. - Umschlag mit leichter Randläsur, Heftklammern angerostet; SEHR GUTES EXEMPLAR DER FRAGILEN PUBLIKATION. / FIRST EDITION, SOFTCOVER ORIGINAL. - Wrapper with minimally used, staples somewhat rusty; A VERY GOOD COPY OF THE FRAGILE PUBLICATION. --- ''Before the beginning of the World War I, the Australia Defence Forces acquired 80,000 acres (approximately 32,375 hectares) of land at Holsworthy. When the Commonwealth Government assented to the War Precautions Act in 1914, it was decided that people who were of German origin or descent, as well as those from countries allied with Germany, might be a security risk, and so places had to be found to detain them. At first people were detained in army barracks or training camps but the government soon realised they would need more permanent accommodation and set up camps in specific locations, one of these being the German Concentration Camp at Holsworthy in the Liverpool district. As early as September 1914 about 100 seamen who had been taken from German and English ships arrived at the camp. Others soon followed from various locations. . .''(see 'The Dictionary of Sydney', online); letzendlich waren es bis zu 6.000 Internierte . . .

Haarfärberei am lebenden Haar. Der Weg vom Lehrling zum Meister des Friseurhandwerks. Vorbereitung auf den theoretischen und praktischen Teil der Meisterprüfung im Friseurhandwerk. Das ABC der Gehilfen- und Meisterprüfung im Friseurhandwerk). Berlin, Verlag Robert Klett, 1928, 1936 (2. Auflage), 1937, 1936 (2. Auflage), 1936, 1936 und 1937, 8°, 179, 87, 103, 174, 135, 189 und 143 s., mit Abbildungen, Original-Leinwandeinband mit Griffregister (lichtrandig, etwas fleckig, Seiten etwas gebräunt).