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Buch. Zustand: Neu. Neuware -In this book applications of cooperative game theory that arise from combinatorial optimization problems are described. It is well known that the mathematical modeling of various real-world decision-making situations gives rise to combinatorial optimization problems. For situations where more than one decision-maker is involved classical combinatorial optimization theory does not suffice and it is here that cooperative game theory can make an important contribution. If a group of decision-makers decide to undertake a project together in order to increase the total revenue or decrease the total costs, they face two problems. The first one is how to execute the project in an optimal way so as to increase revenue. The second one is how to divide the revenue attained among the participants. It is with this second problem that cooperative game theory can help. The solution concepts from cooperative game theory can be applied to arrive at revenue allocation schemes.In this book the type of problems described above are examined. Although the choice of topics is application-driven, it also discusses theoretical questions that arise from the situations that are studied.For all the games described attention will be paid to the appropriateness of several game-theoretic solution concepts in the particular contexts that are considered. The computation complexity of the game-theoretic solution concepts in the situation at hand will also be considered.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 204 pp. Englisch.

Buch. Zustand: Neu. Neuware -The articles in this volume were contributed by the friends of Lucien Le Cam on the occasion of his 70th birthday in November 1994. We wish him a belated happy birthday. In addition to all the usual excuses for our tardiness in the preparation of the volume, we must point to the miracles of modern computing . .Az3 the old proverb almost put it: there's many a slip 'twixt cup and baselineskip. We beg forgiveness of any of our infinitely patient contributors who find that the final product does not quite match with the galley proofs. Our task was also made harder by the sad death of our friend and fellow editor, Erik Torgersen. We greatly appreciate the editorial help of David Donoho with one of the more troublesome contributions. In addition to the 29 contributed articles, we have included a short vita, a list of publications, and a list of Lucien's Ph.D. students. We are also pleased that Lucien allowed us to include a private letter, written to Grace Yang, in response to a query about the extent of his formal mathematical training. The letter gives some insights into what made Lucien one of the leading mathematical statisticians of the century.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 478 pp. Englisch.

Buch. Zustand: Neu. Neuware -Qualitative methodologies in cultural psychology often lack the objective and verifiable character of quantitative analysis. Author Carl Ratner corrects this shortcoming by rigorously systematizing qualitative methods. The book discusses, for example, means of systematizing such subjective reports as interviews, letters, and diaries, which often yield valuable data that is not easily quantified. Ratner argues that 'complex psychological phenomena are expressed through extended responses' and hence are best studied by new, more regularized qualitative methods that go beyond measuring simple, overt responses.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 280 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware - The purpose of this book is to focus on the contribution of one of the most prominent scholars in the strategy field, Michael Porter, from both a practitioner, that is Chief Executive Officer (CEO), perspective, and from a research perspective. Using such a dual perspective may improve the relevance of strategy research for the business community. Four leading chief executives, two from European multinationals (Royal Dutch/Shell Group and Unilever N.V.) and two from important Dutch public organizations (the Port of Rotterdam and the Ministry of Economic Affairs), were invited to reflect on Porter's contributions to four levels of analysis: (1) business level strategy, (2) corporate level strategy, (3) regional competitiveness and finally (4) national competitiveness. Against this background, the book is structured as follows: Chapters 2 to 8 deal with the four mentioned levels of analysis from a dual perspective - theoretical and managerial. The two final chapters aim to find out how Porter's theories are related to each other and whether and how the different levels of analysis can be connected.

Buch. Zustand: Neu. Neuware -This user-friendly, comprehensive guide places evaluation in the context of HIV to give all health care professionals the necessary tools for developing and implementing successful HIV interventions. Every aspect of evaluation is discussed, including: the social and political context of evaluationcoding and inter-rater reliability proceduresbarriers to evaluation and solutionthe dissemination of resultsthe application of theory to HIV interventions.Case studies and examples from both the US and abroad to illustrate practical issues, and numerous tables and figures complement the text.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 316 pp. Englisch.

Buch. Zustand: Neu. Neuware -Food Authentication is an issue that has become increasingly important in recent years, due to the drive for more accurate and truthful labeling. This title provides a guide to the techniques available to establish food authenticity, together with their associated strengths and limitations. It is aimed at food scientists and technologists involved in the issues of adulteration or fortification of food and beverages.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 368 pp. Englisch.

Buch. Zustand: Neu. Neuware - The purpose of this book is to focus on the contribution of one of the most prominent scholars in the strategy field, Michael Porter, from both a practitioner, that is Chief Executive Officer (CEO), perspective, and from a research perspective. Using such a dual perspective may improve the relevance of strategy research for the business community. Four leading chief executives, two from European multinationals (Royal Dutch/Shell Group and Unilever N.V.) and two from important Dutch public organizations (the Port of Rotterdam and the Ministry of Economic Affairs), were invited to reflect on Porter's contributions to four levels of analysis: (1) business level strategy, (2) corporate level strategy, (3) regional competitiveness and finally (4) national competitiveness. Against this background, the book is structured as follows: Chapters 2 to 8 deal with the four mentioned levels of analysis from a dual perspective - theoretical and managerial. The two final chapters aim to find out how Porter's theories are related to each other and whether and how the different levels of analysis can be connected.

Buch. Zustand: Neu. Neuware - This book contains a special issue of the Journal of Real Estate Finance and Economics, comprising thirteen articles on house price measurement. These articles address the various procedures used to compute cross-sectional or temporal house price indices. Specifically, these articles contain research that: (1) evaluates hedonic, repeat sales, or hybrid approaches to constructing house price indices; (2) evaluates alternative sources of data on house prices and corresponding housing characteristics; (3) identifies the most influential land, structural, neighborhood, and proximity determinants of house prices (and associated changes in house prices); (4) provides a methodology for identifying housing market segments; (5) incorporates spatial autocorrelation in house price indices; and (6) provides more accurate estimates of the variance in house prices.

Buch. Zustand: Neu. Neuware -There is currently a high level of interest in the field of nonlinear guided wave optics with the availability of nonlinear materials and their use in new areas of application. This is particularly the case for solitons and other types of nonlinear pulses in optical fibers, high capacity dispersion-free communications. Further, soliton-like beams in highly nonlinear materials, such as organic polymers, are being studied with a view to using them for fast-switching purposes in devices where the light creates its own guiding channel.Written by two authors who are at the forefront of this research, Solitons provides a thorough treatment of the applications of switching devices. It presents the results of the most up to date research on the subject in an accessible manner and adopts a unified approach to solitons in fibers and the devices which use them. The book is an essential reference work for both professional engineers working in optoelectronics and telecommunications companies and graduate students and researchers in the area.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 356 pp. Englisch.

Buch. Zustand: Neu. Neuware -The deployment of communications networks and distributed computing systems requires the use of open, standards-based, integrated management systems. During the last five years, the overall industry effort to develop, enhance, and integrate man agement systems has crystallized in the concept of management platforms. Manage ment platforms are software systems which provide open, multi vendor, multiprotocol distributed management services. They allow multiple management applications to run over core platform services which constitute the essential part of the management platform framework. This book provides a comprehensive analysis of the features and technical character istics of distributed management platforms by examining both qualitative and quanti tative management capabilities required by each management platform service. The analysis covers the management platform run-time environment, the operational aspects of using management platforms, the development environment, which con sists of software toolkits that are used to build management applications, the imple mentation environment, which deals with testing interoperability aspects of using management platforms, and of course the distributed applications services which plat forms make available to management applications. Finally, the analysis covers the capabilities of several management applications, either generic or specific to devices or resources which run on top of management platforms.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 538 pp. Englisch.

Buch. Zustand: Neu. Neuware -The goal of gene transfer is protein expression. a process brought about by the insertion of a gene coding for a foreign protein into target cells resulting in the synthesis of the foreign protein For gene therapy, a tmnsferred therapeutic gene must be expressed at a level beneficial for the patient. This chapter provides an introductory overview of the rapidly evolving field of non-viral approaches for gene delivery to rnarnrnalian cells. Although currently there are fewer ongoing clinical trials using non-viral approaches than those using viral based systems, the number of non-viral trials is increasing. The long range goal of some research groups is the development of a genetically engineered artificial virus targeted to specific cells in the human body. An arurual conference, organized by Cambridge Healthtech Institute entitled 'Artificial Self-Assembling Systems for Gene Transfer', brings together researchers interested in this field [1]. Assembly of an artificial virus is very complex; other research groups aim to develop simpler delivery systems consisting of a plasmid combined with delivery agents. Viral-based systems are very successful for gene delivery, but despite their successes, viral-based systems have some geneml limitations and system-specific limitations. When employing a viml-based system, the following limitations should be considered: ¿ size limitation of the inserted gene due to packaging constraints (e. g. adenovirus, retrovirus) . ¿ potential tumorigenesis (e. g. retrovirus) ¿ potential for insertional mutagenesis (greater than plasmid based systems) ¿ potential imrnunogenicity (e. g. 540 pp. Englisch.

Buch. Zustand: Neu. Neuware - The approach to teaching the concepts of food processing to the undergrad uate food science major has evolved over the past 40 years. In most under graduate food science curricula, food processing has been taught on a commodity basis. In many programs, several courses dealt with processing with emphasis on a different commodity, such as fruits and vegetables, dairy products, meat products, and eggs. In most situations, the emphasis was on the unique characteristics of the commodity and very little empha sis on the common elements associated with processing of the different commodities. Quite often the undergraduate student was allowed to select one or two courses from those offered in order to satisfy the minimum standards suggested by the Institute of Food Technologists. The current 1FT minimum standards suggest that the undergradu ate food science major be required to complete at least one food processing course. The description of this course is as follows: One course with lecture and laboratory which covers general characteristics of raw food materials, principles offood preserva tion, processing factors that influence quality, packaging, water and waste management, and sanitation. Prerequisites: general chemistry, physics, and general microbiology.

Buch. Zustand: Neu. Neuware -In this volume, readers are introduced to Vygotsky's argument for a theoretical and methodological approach to differentiate A 'higher' mental functions from the more basic brain processes that other theorists believed were at the center of the psychological apparatus. The famed Soviet psychologist's view of developmental issues as an intricately woven tapestry of functions includes analyses of: the development of speech and written language the mastering of attention and mnemonic skills self-control and the higher, more cultivated forms of behavior the cultural age, personality, and world view of children.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 316 pp. Englisch.

Buch. Zustand: Neu. Neuware -Blood Stem Cell Transplantation conveys the excitement that accompanies the newest developments in hematopoietic stem cell transplantation. Some of the applications that stand to impact this field most significantly are based on recent advances in the biological sciences, as demonstrated by the chapters on gene therapy, on the detection of minimal residual disease using molecular techniques, and on the use of radioimmunoconjugates targeting lymphoma and leukemia-associated antigens. Others are the results of clinical observations - e.g., the association between graft-versus-host- disease (GVHD) and durable remissions that have led to creative clinical experiments such as donor leukocyte infusions (DLI). Attempts to unravel the biological events that underlie the responses seen in patients with relapsed chronic myelogenous leukemia treated with DLI are likely to provide the basis for future refinements in this clinical approach. Hopefully, improved response rates and reduced toxicity will result. The power of the immunologic response in controlling malignant disease is underscored in the chapter on post-transplant immunotherapy. The complex immunologic process that results in clinical GVHD may be dissected and engineered to provide clinical benefits that include, in addition to its antineoplastic effects, the amelioration of its clinical manifestations. Better control of GVHD with less global immunosuppression will facilitate the use of mismatched and unrelated donors. This area of investigation perfectly illustrates the continued interplay between the laboratory and the clinic. The continued cross-fertilization of ideas between immunologists, molecular biologists and clinical investigators is likely to yield important advances in this field for years to come.Possible applications of stem cell transplantation continue to grow with the identification of alternative sources of stem cells and the potential to engineer and/orexpand the graft. Although the use of unrelated and mismatched donors continues to increase, the possibilities associated with umbilical cord blood transplantation are legion, especially if stem cells can be expanded ex vivo to provide grafts for full-sized adults. Using techniques in which contaminating malignant cells may be eliminated from autografts through positive selection, autologous transplantation may prove highly effective, especially when coupled with post-transplant immunotherapy. Some of these same methodologies have helped facilitate the use of autologous grafts for transplantation in patients with chronic myelogenous leukemia without allogeneic donors.Advances in the supportive care of transplant patients, including the pretransplant identification of those at risk from pulmonary complications and the use of cytokines to speed engraftment, have reduced morbidity and mortality to such a degree that it is appropriate to consider high-dose therapy and stem cell reconstitution in patients with nonmalignant diseases. The impressive advances that have occurred in transplantation for thalassemia are described by pioneers in their area of investigation. The burgeoning field of transplantation for autoimmune disorders, including its immunobiologic basis and soon-to- be-realized clinical potential, is also summarized. Continued progress in the use of high-dose therapy with stem cell rescue for the treatment of pediatric tumors, which derives in part from improved supportive care, is detailed.The sobering voice of the health care economists underscores the necessary limitations to our seemingly unbridled imagination. Cost- consciousness and financial know-how will need to be reflected in future study designs. Given the seemingly endless applications of our technology, strategies to insure its cost-effectiveness will be necessary. Continued financial support for laboratory investigatiSpringer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 436 pp. Englisch.

Buch. Zustand: Neu. Neuware - Now in its second edition, this authoritative reference provides comprehensive coverage of the fundamentals of powder science and technology and builds upon them, emphasizing practical applications in the design, production, processing, and handling of applications. The book features contributors from twenty-one internationally renowned and respected professionals and researchers in the field. Their chapters focus on problem solving, but also provide a solid link between theory and practise. Organized in a logical manner, this handbook begins by introducing the reader to the fundamentals of solid particulates, covering the concept of particle size measurement and analysis, surface characteristics, structural properties of packings of particles, and rheological properties of particles. The remainder of the book provides a thorough treatment of known and potential applications of powder technology, including a literature survey, problem applications, case histories, and design parameters. Extensive updates have been made to all of the chapters, references, problems, and case histories, reflecting new developments in the technology of powder science. Additions to the book include three new chapters on: health hazards for respirable dust, dense phase pneumetic conveying, and dust explosions and fire hazards. The Handbook of Powder Science and Technology, Second Edition can be used as a reference for those who have little or no experience in powder technology. It serves equally well as a manual and handbook for technologists, design engineers and scientists who have previous experience with powders. It is also a useful reference for research or as a textbook for senior undergraduate and graduate courses.