Springer us jan 2003 (2 Ergebnisse)
- Hardcover
Anbieter: AHA-BUCH GmbH, Einbeck, DeutschlandAHA-BUCH GmbH
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EUR 304,50
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Buch. Zustand: Neu. Neuware - Cellular signaling in cardiac muscle refers to the myriad of stimuli and responses that direct and control the physiological operation of this organ. Our understand ing of these complex signaling cascades has increased dramatically over the past few decades with the advent of molecular tools for the…ir dissection. Moreover, this infor mation is beginning to provide tangible targets towards manipulating cardiac func tion in the setting of cardiovascular disease. The mechanisms and factors that regulate cardiac cell growth are of particular interest as both adaptive and maladaptive responses can occur during cardiac hypertrophy. Cardiac hypertrophy describes the increase in individual cardiac myocyte size that is accomplished through the series and/or parallel addition of sarcomeres. The ability of cardiac muscle to increase in size through hyperplasia becomes highly restricted or negligible shortly after birth. Consequently, the increase in heart size associated with development and growth of an individual occurs through hypertrophy. In response to a chronic increase in workload, cardiac muscle cells can dramatically increase in size to face their increasing contractile demands. While this plasticity is clearly a ben eficial response under many conditions, it can be highly deleterious and inappropri ate under others. For example, cardiac hypertrophy associated with endurance exercise clearly enhances athletic performance. In contrast, the hypertrophy associated with chronic hypertension, stenotic or regurgitant heart valves, or following a myocardial infarction often continues far beyond the period where this adaptive response is ben eficial.
Sprache: Englisch
Verlag: Springer Us Jan 2003, 2003
Serie: Buch 48 von 323 - International Series in Operations Research & Management Science
- Hardcover
Anbieter: AHA-BUCH GmbH, Einbeck, DeutschlandAHA-BUCH GmbH
Verkäufer/-in kontaktierenVerkäufer/-in mit 5 SternenZustand: Neu
EUR 474,63
EUR 65,70 VersandVersand von Deutschland nach USAAnzahl: 2 verfügbar
Buch. Zustand: Neu. Neuware - Over the past thirty-five years, a substantial amount of theoretical and empirical scholarly research has been developed across the discipline domains of Transportation. This research has been synthesized into a systematic handbook that examines the scientific concepts, methods, and principles of th…is growing and evolving field. The Handbook of Transportation Science outlines the field of transportation as a scientific discipline that transcends transportation technology and methods. Whether by car, truck, airplane - or by a mode of transportation that has not yet been conceived - transportation obeys fundamental properties. The science of transportation defines these properties, and demonstrates how our knowledge of one mode of transportation can be used to explain the behavior of another. Transportation scientists are motivated by the desire to explain spatial interactions that result in movement of people or objects from place to place. Its methodologies draw from physics, operations research, probability and control theory.
