birkhäuser basel birkhäuser basel dez 2005 (3 Ergebnisse)

Buch. Zustand: Neu. Neuware -This book offers a panorama of recent advances in the theory of infinite groups. It contains survey papers contributed by leading specialists in group theory and other areas of mathematics. Topics include amenable groups, Kaehler groups, automorphism groups of rooted trees, rigidity, C\*-algebras, random walks on groups, pro-p groups, Burnside groups, parafree groups, and Fuchsian groups. The accent is put on strong connections between group theory and other areas of mathematics.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 428 pp. Englisch.

Buch. Zustand: Neu. Neuware -It is evident that a defective or deregulated complement system results in kidney diseases. An important role of complement effector and regulatory proteins in pathological settings of the kidney has been demonstrated. A large panel of distinct human kidney diseases is caused by defective complement control. Genetic analyses have identified mutations in complement regulators that are associated with these diseases. Mutations have been identified in the fluid phase alternative pathway regulator Factor H and the membrane regulator Membrane Cofactor Protein MCP (CD46). The functional characterization of the mutant proteins allows to define the pathophysiological events on a molecular level. These new concepts and data on disease mechanisms allowed establishing new diagnostic and promising therapeutic approaches for several human kidney diseases. Molecular biology, clinics and therapy are discussed in this volume.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 260 pp. Englisch.

Buch. Zustand: Neu. Neuware -A repertoire of 10 TLRs mediate the first response to all microbes that infect mammals. They are the long sought receptors for a wide range of microbial products. Notable examples include TLR4 which recognizes LPS from gram negative bacteria, TLR3 which recognizes viral double-stranded RNA and TLR9 which recognizes CpG DNA motifs, found commonly in both viruses and bacteria. TLRs are increasingly being implicated in both infectious and inflammatory diseases, notable examples being sepsis, inflammatory bowel disease, atherosclerosis and asthma. There is therefore great interest in targeting TLRs therapeutically since blocking TLRs will result in a decrease in the production of inflammatory mediators such as TNF. This volume covers our current understanding of TLRs, and their role in inflammation. Given the primacy of TLRs in the inflammatory process and their emerging role in inflammatory diseases the book is of great interest to researchers working in inflammation and immunology.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 260 pp. Englisch.