Gap junctions (36 Ergebnisse)

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Taschenbuch. Zustand: Neu. Gap Junctions in the Nervous System | David C. Spray (u. a.) | Taschenbuch | Einband - flex.(Paperback) | Englisch | 2013 | Springer | EAN 9783662219379 | Verantwortliche Person für die EU: Springer Heidelberg, Tiergartenstr. 17, 69121 Heidelberg, buchhandel-buch[at]springer[dot]com | Anbieter: preigu. …

Zustand: New. 1. Gap Junctions in the Nervous System: An Introduction.- 2. Molecular Diversity and Plasticity of Gap Junctions in the Nervous System.- 3. Physiological Properties of Gap Junction Channels in the Nervous System.- 4. Gap Junctions as Electrical Synapses.- 5.

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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - A Cytoplasm Connexon or Hemichannel Cytoplasm external loop I - P. M. N-Termlnus Fig. 1. 1. Topology of gap junction channels. (A) Cap junction channels, extending from the cytoplasm of one cell to the cytoplasm of another, are formed by two connexons or hemichannels connected across extracellular space. (B) Each connexon is formed from six connexin subunits, each having four membrane-spanning domains and both amino and carboxyl termini within the cytoplasm. External/oops (I and II} are believed to provide the high affinity interactions between the hemichannels. 4 Gap }unctions in the Nervous System P-region of voltage sensitive nonjunctional molecules; these contributed disulfide 9 channels. And Delmar's group has ob bridges are presumably involved in intra tained evidence that intracellular acidifi connexin and inter-EL loop tertiary struc cation may result in a conformational ture. An old observation that should be change analogous to the ball and chain repeated stoichiometrically with modern techniques is that gap junction channels model of inactivation of voltage gated ionic can be split into connexons or hemi channels, whereby the carboxyl terminal channels using hyperosmotic disaccharide portion of connexin43 binds to CL, closing 23 solutions again implying that linkage is the channel. Higher order structure of the channel not covalent. is believed to consist of six connexins form ing the hemichannel or connexon in a 3.…

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Zustand: Sehr gut. Zustand: Sehr gut | Seiten: 304 | Sprache: Englisch | Produktart: Bücher | It has been long thought that intercellular communication in the adult mammalian brain is exclusively mediated by neurotransmission at chemical synapses. However, evidence from molecular, biological, electrophysiological, pharmacological, and genetic research has accumulated indicating that electrical synapses (or gap junctions) in the adult brain also contribute to intercellular communication. Gap junctions between glial cells or neurons are ubiquitously expressed in the mammalian brain and play a role in brain development, including cell differentiation, cell migration and survival, and tissue homeostasis as well as in human diseases including hearing loss, neuropathies, epilepsy, brain trauma, and cardiovascular disease. This book provides the most current and comprehensive reference available covering the physiological, behavioral and pathophysiological roles of gap junctions in the brain. It is geared for use by researchers, clinicians, and students. …

Taschenbuch. Zustand: Neu. Gap Junctions in Development and Disease | Elke Winterhager | Taschenbuch | xvii | Englisch | 2010 | Springer | EAN 9783642065590 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.…

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Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Communication between cells via intercellular channels - gap junctions - appears essential to certain developmental processes and appropriate organ function. Gap Junctions in Development and Disease aims to describe the molecular events underlying impaired development and disease. Beginning with a comprehensive review of various mouse and human genes encoding the channel-forming connexins, later chapters describe several connexin mutations associated with human diseases such as hereditary deafness and female infertility. Erroneous signaling mediated by the interaction of mutant connexins with other proteins, thought to be responsible for dysfunction of organs such as heart, muscle, brain, skin, lens, placenta, and endocrine tissue in both mice and men, is also addressed.Although the question of why some mutations in gap-junction proteins lead to specific phenotypes remains to be answered, the reviews in this book provide an intriguing insight into the future direction of this research field.…

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Communication between cells via intercellular channels - gap junctions - appears essential to certain developmental processes and appropriate organ function. Gap Junctions in Development and Disease aims to describe the molecular events underlying impaired development and disease. Beginning with a comprehensive review of various mouse and human genes encoding the channel-forming connexins, later chapters describe several connexin mutations associated with human diseases such as hereditary deafness and female infertility. Erroneous signaling mediated by the interaction of mutant connexins with other proteins, thought to be responsible for dysfunction of organs such as heart, muscle, brain, skin, lens, placenta, and endocrine tissue in both mice and men, is also addressed.Although the question of why some mutations in gap-junction proteins lead to specific phenotypes remains to be answered, the reviews in this book provide an intriguing insight into the future direction of this research field.…

Paperback. Zustand: Brand New. 296 pages. 9.00x6.00x0.71 inches. In Stock.