Anbieter: Ria Christie Collections, Uxbridge, Vereinigtes Königreich
EUR 115,23
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In den WarenkorbZustand: New. In.
EUR 162,51
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In den WarenkorbKartoniert / Broschiert. Zustand: New.
Sprache: Englisch
Verlag: Birkhäuser Basel, Birkhäuser Basel, 2013
ISBN 10: 3034897774 ISBN 13: 9783034897778
Anbieter: AHA-BUCH GmbH, Einbeck, Deutschland
Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Inhibition of the proton pump in the parietal cells has been established as the main therapeutic principle in the treatment of acid-related diseases, such as peptic ulcer and gastro-oesophageal reflux. The proton pump inhi bitors are tailored for their purpose. They accumulate in the target cell, are activated by acid and bind strongly to the specific target - the proton pump. The clinical superiority of the proton pump inhibitors is due not only to their high efficacy but also to the long duration of the acid inhibition in comparison with other antisecretory drugs. At present when drug discovery mostly relies on identification and characterization of potential targets by genome research, molecular biology, combinatorial chemistry and automated screening, it seems worthwhile to present the development of the tITst proton pump inhibitor - omeprazol- starting from a chemical structure with an observed antisecretory effect but also severe toxic effects that had to be eliminated. As always, basic and applied research operate luind in hand to optimize the delicate balance be tween efficacy and safety of a new drug. This goal often involves time and many different specialists.
Anbieter: Revaluation Books, Exeter, Vereinigtes Königreich
EUR 271,88
Anzahl: 2 verfügbar
In den WarenkorbPaperback. Zustand: Brand New. 1999 edition. 268 pages. 9.60x6.69x0.61 inches. In Stock.
Zustand: New. Editor(s): Olbe, Lars. Series: Milestones in Drug Therapy. Num Pages: 261 pages, biography. BIC Classification: MB. Category: (P) Professional & Vocational. Dimension: 244 x 170 x 14. Weight in Grams: 467. . 2013. 1999th Edition. paperback. . . . . Books ship from the US and Ireland.