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Hardcover. Zustand: Très bon. Ancien livre de bibliothèque avec équipements. Edition 2009. Ammareal reverse jusqu'à 15% du prix net de cet article à des organisations caritatives. ENGLISH DESCRIPTION Book Condition: Used, Very good. Former library book. Edition 2009. Ammareal gives back up to 15% of this item's net price to charity organizations.

Zustand: Sehr gut. Zustand: Sehr gut | Seiten: 259 | Sprache: Englisch | Produktart: Bücher | Keine Beschreibung verfügbar.

Zustand: New. In English.

Taschenbuch. Zustand: Neu. Marine Toxins as Research Tools | Nobuhiro Fusetani (u. a.) | Taschenbuch | xiv | Englisch | 2010 | Springer | EAN 9783642099687 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.

Gebunden. Zustand: New. Highlights the crucial importance of marine toxins as research tools and potential drugs Marine organisms produce a wide array of toxins, many of which are not only structurally unusual, but also show potent and interesting modes of action. Si.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Marine organisms produce a wide array of toxins, many of which are not only structurally unusual, but also show potent and interesting modes of action. Since the discovery of tetrodotoxin, a pufferfish toxin, as a potent and selective blocker of Na+ channels in 1964, it has been widely used as a research tool in pharmacological and physiological research. This has led to the identification of a number of important biological functions for Na+ channels. In recent years, much biological research has been carried out at molecular and cellular levels, and therefore selective inhibitors of enzymes and selective antagonist/agonists of receptors and channels have become increasingly important research tools. Accordingly, interest in using such compounds as reagents has increased. Marine toxins are some of the most popular research tools and have already contributed much to our understanding of biological processes and disease mechanisms.

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Marine organisms produce a wide array of toxins, many of which are not only structurally unusual, but also show potent and interesting modes of action. Since the discovery of tetrodotoxin, a pufferfish toxin, as a potent and selective blocker of Na+ channels in 1964, it has been widely used as a research tool in pharmacological and physiological research. This has led to the identification of a number of important biological functions for Na+ channels. In recent years, much biological research has been carried out at molecular and cellular levels, and therefore selective inhibitors of enzymes and selective antagonist/agonists of receptors and channels have become increasingly important research tools. Accordingly, interest in using such compounds as reagents has increased. Marine toxins are some of the most popular research tools and have already contributed much to our understanding of biological processes and disease mechanisms.

Hardcover. Zustand: Brand New. 1st edition. 259 pages. 9.50x6.50x0.75 inches. In Stock.

Paperback. Zustand: Brand New. 273 pages. 9.25x6.10x0.65 inches. In Stock.

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book presents the structure of the main toxins of aquatic origin, their distribution, producing species and vectors, their mechanisms of action, the clinical aspects of envenomation in humans, their effects in laboratory or wild animals, their toxicokinetic properties, including the relevant treatment, detection methods and regulatory aspects for management. The work also presents the main species associated with the injuries, poisonings their toxins, mechanism of action and the clinical aspects of the envenomations by aquatic animals and discusses the actual measures utilized in the first aid and hospital treatments. Marine toxins such as palytoxins, brevetoxins, saxitoxin, ciguatoxins, okadaic acid, azaspiracid toxins, equinatoxins are also dealt with in this volume. These toxins can be lethal as well as having a complex and large molecular structure and display mechanisms by which they act very specifically on targets, receptors or on critical body proteins.Themarine and freshwater environments are the new frontiers of humanity, but the increase of economic and tourist activities provoke nasty encounters between aquatic animals and humans. The main victims are swimmers, professional and sportive fishermen, surfers and scuba divers as well as people working in related fields. The identification, knowledge and treatment of envenomations caused by venomous and poisonous animals are not adequate and the prevention of injuries still is not possible. Additionally, the immense potential of the pharmacologic effects of their toxins is not fully explored. Toxins of venomous aquatic animals can cause proteolysis, myotoxicity, hemotoxicity (mainly hemolysis), cytotoxicity and neurotoxicity. The neurotoxicity is generally associated with toxins of dinoflagellates and cyanobacteria, present in poisonous and/or contaminated invertebrates and fish.