Hardcover. Zustand: Good. No Jacket. Pages can have notes/highlighting. Spine may show signs of wear. ~ ThriftBooks: Read More, Spend Less.
Anbieter: PsychoBabel & Skoob Books, Didcot, Vereinigtes Königreich
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In den WarenkorbHardcover. Zustand: Very Good. Hardcover (no jacket) in very good condition. A few minor bumps to the edges and leading corners. Pages are clean; all content is clear. CM. Used.
Anbieter: Books From California, Simi Valley, CA, USA
hardcover. Zustand: Very Good.
Sprache: Englisch
Verlag: Emerald Group Publishing Limited, 2012
ISBN 10: 1780520026 ISBN 13: 9781780520025
Anbieter: WeBuyBooks, Rossendale, LANCS, Vereinigtes Königreich
EUR 106,87
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In den WarenkorbZustand: Very Good. Most items will be dispatched the same or the next working day. A copy that has been read, but is in excellent condition. Pages are intact and not marred by notes or highlighting. The spine remains undamaged.
Zustand: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher | Neurodegenerative disorders are common and devastating. Rationally, the most effective treatments will target pathogenetic mechanisms. While alternative - proaches, based on alleviating the symptoms of patients with Alzheimer disease, Parkinson disease, Huntington disease, prion disorders or amyotrophic lateral sc- rosis, can be expected to reduce suffering, studies of pathogenesis of these a- related disorders will be most important for enabling early diagnosis and the creation of preventative and curative treatments. It is in this context that a recent IPSEN rd meeting (The 23 Colloque Medecine ¿ et Recherche, April 28, 2008) focused on a role for disruption of intracellular traf?cking in neurodegenerative disorders. The meeting captured emerging insights into pathogenesis from disrupted traf?cking and processing of proteins implicated in age-related degeneration. Protein folding, traf?cking and signaling were the principal topics covered at the meeting. Importantly, the presenters pointed to the importantly intersection of these themes. While the proteolytic processing of APP into its toxic product, the A? peptide, is an intensive focus of work in many laboratories, it is only relatively recently that investigators have begun to examine in depth the cellular compartments and traf?cking events that mediate APP processing and how derangement of tr- ?cking pathways could impact them.
Sprache: Englisch
Verlag: Emerald Publishing Limited, 1999
ISBN 10: 0762305053 ISBN 13: 9780762305056
Anbieter: Ria Christie Collections, Uxbridge, Vereinigtes Königreich
EUR 135,90
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In den WarenkorbZustand: New. In.
Sprache: Englisch
Verlag: Emerald Publishing Limited, 2011
ISBN 10: 0857244671 ISBN 13: 9780857244673
Anbieter: Ria Christie Collections, Uxbridge, Vereinigtes Königreich
EUR 159,45
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In den WarenkorbZustand: New. In.
Sprache: Englisch
Verlag: Emerald Publishing Limited, 2012
ISBN 10: 1780520026 ISBN 13: 9781780520025
Anbieter: Ria Christie Collections, Uxbridge, Vereinigtes Königreich
EUR 173,29
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In den WarenkorbZustand: New. In.
Anbieter: Ria Christie Collections, Uxbridge, Vereinigtes Königreich
EUR 227,33
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In den WarenkorbZustand: New. In.
EUR 229,98
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In den WarenkorbHardcover. Zustand: Brand New. 1st edition. 323 pages. 9.00x6.25x1.25 inches. In Stock.
Taschenbuch. Zustand: Neu. Intracellular Traffic and Neurodegenerative Disorders | William C. Mobley (u. a.) | Taschenbuch | xiv | Englisch | 2010 | Springer-Verlag GmbH | EAN 9783642099724 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
Sprache: Englisch
Verlag: Springer Berlin Heidelberg, Springer Berlin Heidelberg, 2008
ISBN 10: 3540879404 ISBN 13: 9783540879404
Anbieter: AHA-BUCH GmbH, Einbeck, Deutschland
Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book explores the role of sub-cellular trafficking in the pathogenesis, treatment and prevention of neurodegenerative diseases. Recent findings point to faulty trafficking as contributing to the dysfunction and degeneration of neurons and neural circuits. Increasingly, research is targeting the mechanisms responsible and means to address them therapeutically. Many adult onset neurodegenerative diseases appear to arise from the accumulation of misfolded, neurotoxic peptides. This book investigates the ways in which sub-cellular trafficking pathways play a role both in the pathological accumulation of these misfolded proteins and in attempts to clear them. Because subcellular protein trafficking has an important role in the biology of neuronal function and survival, this also addresses how trophic factors maintain cell: cell interactions and how the underlying mechanisms may be compromised in neurodegenerative diseases. Examples where the use of such trophic factors may provide a way to modify neurodegenerative diseases are investigated.
Sprache: Englisch
Verlag: Springer Berlin Heidelberg, 2010
ISBN 10: 3642099726 ISBN 13: 9783642099724
Anbieter: AHA-BUCH GmbH, Einbeck, Deutschland
Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book explores the role of sub-cellular trafficking in the pathogenesis, treatment and prevention of neurodegenerative diseases. Recent findings point to faulty trafficking as contributing to the dysfunction and degeneration of neurons and neural circuits. Increasingly, research is targeting the mechanisms responsible and means to address them therapeutically. Many adult onset neurodegenerative diseases appear to arise from the accumulation of misfolded, neurotoxic peptides. This book investigates the ways in which sub-cellular trafficking pathways play a role both in the pathological accumulation of these misfolded proteins and in attempts to clear them. Because subcellular protein trafficking has an important role in the biology of neuronal function and survival, this also addresses how trophic factors maintain cell: cell interactions and how the underlying mechanisms may be compromised in neurodegenerative diseases. Examples where the use of such trophic factors may provide a way to modify neurodegenerative diseases are investigated.
EUR 297,87
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In den WarenkorbHardcover. Zustand: Brand New. 377 pages. 9.50x6.50x1.25 inches. In Stock.
Anbieter: Revaluation Books, Exeter, Vereinigtes Königreich
EUR 303,91
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In den WarenkorbHardcover. Zustand: Brand New. 1st edition. 183 pages. 9.25x6.25x0.50 inches. In Stock.
Anbieter: Revaluation Books, Exeter, Vereinigtes Königreich
EUR 318,36
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In den WarenkorbPaperback. Zustand: Brand New. 198 pages. 9.00x6.00x0.47 inches. In Stock.
EUR 329,40
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In den WarenkorbHardcover. Zustand: Brand New. 421 pages. 9.00x6.25x1.25 inches. In Stock.