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In den WarenkorbZustand: New. pp. 376.
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hardcover. Zustand: Fine.
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In den WarenkorbPaperback. Zustand: Brand New. 308 pages. 6.69x0.67x9.61 inches. In Stock.
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In den WarenkorbZustand: New. Multifunctional Cement-Based Sensors for Intelligent Infrastructure: Design, Fabrication and Application covers the development and use of cement-based sensors for monitoring structural health, durability, and environment.
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In den WarenkorbHardcover. Zustand: Brand New. 392 pages. 11.25x8.75x1.00 inches. In Stock.
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Zustand: New. Editor(s): Li, Wenkui; Lee, Mike S. Series: Wiley Series on Pharmaceutical Science and Biotechnology: Practices, Applications and Methods. Num Pages: 376 pages, illustrations. BIC Classification: MBGL; MMF; PNF. Category: (P) Professional & Vocational. Dimension: 225 x 288 x 24. Weight in Grams: 1110. . 2014. 1st Edition. Hardcover. . . . . Books ship from the US and Ireland.
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In den WarenkorbZustand: New. In that, it serves as a source of information and of literature references for further in-depth reading. It is very useful to have but, like always, it does not give all answers to every question one may have. (ChemMedChem, 1 June 2014)WENKUI LI, PhD,.
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In den WarenkorbZustand: New. Über den AutorWENKUI LI is a Senior Fellow at the Novartis Institutes for BioMedical Research Pharmacokinetic Sciences. He serves on the Editorial Board of Biomedical Chromatography. WENYING JIAN is a Senior Prin.
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In den WarenkorbZustand: New. 2019. 1st Edition. Hardback. . . . . . Books ship from the US and Ireland.
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In den WarenkorbHardcover. Zustand: Brand New. 400 pages. 11.25x8.50x0.75 inches. In Stock.
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In den WarenkorbHardcover. Zustand: Brand New. 1st edition. 704 pages. 11.00x8.75x1.50 inches. In Stock.
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Buch. Zustand: Neu. Neuware - Revised and Expanded Handbook Provides Comprehensive Introduction and Complete Instruction for Sample Preparation in Vital Category of Bioanalysis Following in the footsteps of the previously publishedHandbook of LC-MS Bioanalysis, this book is a thorough and timely guide to all important sample preparation techniques used for quantitative Liquid Chromatography-Mass Spectrometry (LC-MS) bioanalysis of small and large molecules. LC-MS bioanalysis is a key element of pharmaceutical research and development, post-approval therapeutic drug monitoring, and many other studies used in human healthcare. While advances are continually being made in key aspects of LC-MS bioanalysis such as sensitivity and throughput, the value of research/study mentioned above is still heavily dependent on the availability of high-quality data, for which sample preparation plays the critical role. Thus, this text provides researchers in industry, academia, and regulatory agencies with detailed sample preparation techniques and step-by-step protocols on proper extraction of various analyte(s) of interest from biological samples for LC-MS quantification, in accordance with current health authority regulations and industry best practices. The three sections of the book with a total of 26 chapters cover topics that include: - Current basic sample preparation techniques (e.g., protein precipitation, liquid-liquid extraction, solid-phase extraction, salting-out assisted liquid-liquid extraction, ultracentrifugation and ultrafiltration, microsampling, sample extraction via electromembranes) - Sample preparation techniques for uncommon biological matrices (e.g., tissues, hair, skin, nails, bones, mononuclear cells, cerebrospinal fluid, aqueous humor) - Crucial aspects of LC-MS bioanalytical method development (e.g., pre-analytical considerations, derivation strategies, stability, non-specific binding) in addition to sample preparation techniques for challenging molecules (e.g., lipids, peptides, proteins, oligonucleotides, antibody-drug conjugates) Sample Preparation in LC-MS Bioanalysiswill prove a practical and highly valuable addition to the reference shelves of scientists and related professionals in a variety of fields, including pharmaceutical and biomedical research, mass spectrometry, and analytical chemistry, as well as practitioners in clinical pharmacology, toxicology, and therapeutic drug monitoring.
Buch. Zustand: Neu. Neuware - Consolidates the information LC-MS bioanalytical scientists need to analyze small molecules and macromoleculesThe field of bioanalysis has advanced rapidly, propelled by new approaches for developing bioanalytical methods, new liquid chromatographic (LC) techniques, and new mass spectrometric (MS) instruments. Moreover, there are a host of guidelines and regulations designed to ensure the quality of bioanalytical results.Presenting the best practices, experimental protocols, and the latest understanding of regulations, this book offers a comprehensive review of LC-MS bioanalysis of small molecules and macromolecules. It not only addresses the needs of bioanalytical scientists working on routine projects, but also explores advanced and emerging technologies such as high-resolution mass spectrometry and dried blood spot microsampling.Handbook of LC-MS Bioanalysis features contributions from an international team of leading bioanalytical scientists. Their contributions reflect a review of the latest findings, practices, and regulations as well as their own firsthand analytical laboratory experience. The book thoroughly examines:\* Fundamentals of LC-MS bioanalysis in drug discovery, drug development, and therapeutic drug monitoring\* The current understanding of regulations governing LC-MS bioanalysis\* Best practices and detailed technical instructions for LC-MS bioanalysis method development, validation, and stability assessment of analyte(s) of interest\* Experimental guidelines and protocols for quantitative LC-MS bioanalysis of challenging molecules, including pro-drugs, acyl glucuronides, N-oxides, reactive compounds, and photosensitive and autooxidative compoundsWith its focus on current bioanalytical practice, Handbook of LC-MS Bioanalysis enables bioanalytical scientists to develop and validate robust LC-MS assay methods, all in compliance with current regulations and standards.
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EUR 329,21
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In den WarenkorbHardcover. Zustand: Brand New. 360 pages. 9.68x6.87x9.61 inches. In Stock.