W rook (26 Ergebnisse)

Zustand: Very Good. 2 Edition. Pages intact with possible writing/highlighting. Binding strong with minor wear. Dust jackets/supplements may not be included. Stock photo provided. Product includes identifying sticker. Better World Books: Buy Books. Do Good.

Zustand: Good. 2 Edition. Pages intact with minimal writing/highlighting. The binding may be loose and creased. Dust jackets/supplements are not included. Stock photo provided. Product includes identifying sticker. Better World Books: Buy Books. Do Good.

Paperback. Zustand: Fair. No Jacket. Former library book; Readable copy. Pages may have considerable notes/highlighting. ~ ThriftBooks: Read More, Spend Less.

Zustand: Good. 2 Edition. Former library copy. Pages intact with minimal writing/highlighting. The binding may be loose and creased. Dust jackets/supplements are not included. Includes library markings. Stock photo provided. Product includes identifying sticker. Better World Books: Buy Books. Do Good.…

Paperback. Zustand: Very Good. Shipped within 24 hours from our UK warehouse. Clean, undamaged book with no damage to pages and minimal wear to the cover. Spine still tight, in very good condition. Remember if you are not happy, you are covered by our 100% money back guarantee.

Zustand: Very Good. : Sumérgete en la época dorada de la ficción criminal con 'The Shadows of Sherlock Holmes'. Esta fascinante colección de historias presenta detectives, agentes criminales y estafadores de la alta sociedad. Encontrarás relatos llenos de misterio, suspense y acertijos ingeniosos, con personajes como The Crime Doctor, el Profesor Augustus S.F.X. Van Dusen, Max Carrados, Skin o' My Teeth y el ingenioso detective francés Eugene Valmont. En el lado opuesto de la ley, conocerás a Raffles y Simon Carn, el Príncipe de los Estafadores. Esta edición incluye relatos de autores clásicos como Edgar Allan Poe, Wilkie Collins y Anton Chekhov. EAN: 9781853267444 Tipo: Libros Categoría: Literatura y Ficción Título: The Shadows of Sherlock Holmes Autor: Guy Boothby| Bret Harte| Jacques Futrelle| David Stuart Davies| Hesketh Vernon Hesketh-Prichard| Clarence Rook| Herbert George Jenkins| Anton Pavlovich Chekhov| Robert Barr| Grant Allen| E. W. Hornung| J. E. Preston Muddock| Edgar Allan Poe| Guy Clifford| Emmuska Orczy, Baroness Orczy| Catherine Louisa Pirkis| Anonymous| Ernest Bramah Editorial: Wordsworth Classics Idioma: en Páginas: 357 Formato: tapa blanda. …

Paperback. Zustand: Brand New. 228 pages. In Stock. Oteri, Michaela (illustrator).

1e dr. - Gebonden.

Hardcover. Zustand: Very Good. Zustand des Schutzumschlags: Very Good. First Edition. Publisher's hardback in very good condition: firm, square and tight with no snags or splits, just a trifle rubbed. Complete with original dustjacket: in decent shape, just slightly rubbed and moderately edge-worn. Contents sound and clean; no pen-marks, just a Medical College bookplate at the endpaper. Thus a tidy book in presentable condition. …

Zustand: Poor. This is an ex-library book and may have the usual library/used-book markings inside.This book has soft covers. Book contains pen & pencil markings. In poor condition, suitable as a reading copy. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,1150grams, ISBN:0761916970.…

Zustand: Very good. 1935, London, Seeley, Service & Co. Limited, pp472, colour frontispiece, black and white illustrations, original beige cloth. With a beautifully hand written presentation on front endpaper.

Zustand: New. In English.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The fact that certain adrenal steroid hormones are immunosuppressive and anti-inflammatory has been known for many years, and is routinely exploited by physicians. These effects are attributable to glucocorticoid steroids such as cortisol. Pharmacological doses of glucocorticoids inhibit most or all T cell types. However we now know that the effect of exposure to raised physiological levels is mainly to drive developing lymphocyte responses towards a Th2 cytokine profile (interleukin-4 secreting) while suppressing the development ofThi (gamma interferon secreting) lymphocytes. Only recently have two further regulatory mechanisms become appar ent. First, these effects of cortisol are balanced by pro-inflammatory and ThI-enhancing effects of another adrenal steroid, dehydroepiandro sterone sulfate (DHEAS). Second, the activity of cortisol is directly modulated by enzymes in the target organs and lymphoid tissues that convert it into inactive cortisone. This new information leads to the possibility that immunoregulatory steroids could be used by physicians in novel ways. We can envisage steroid combinations that exploit the anti-inflammatory effects of corti sol, while the Thi-suppressing and Th2-promoting properties of these hormones are opposed by derivatives of DHEAS. Such therapies are already proving effective in animal models of infection, and could revol utionize treatment of Th2-mediated diseases such as asthma, where the anti-inflammatory effects of cortisol are desirable but the effects on T lymphocyte differentiation are not.…

Pp. Zustand: Sehr gut. XII, 305 S. : Ill., graph. Darst. ; 24 cm Die Kernaussage: Moderne Lebensbedingungen reduzieren die Exposition gegenüber Mikroorganismen mit Folgen für die Regulation des Immunsystems und die Zunahme chronisch-entzündlicher Erkrankungen. Die Pämisse: Rook beschreibt, dass der Übergang vom Jäger-Sammler-Leben zu modernen Industriegesellschaften die Mikrobenexposition drastisch reduziert hat. Dies führt zu Fehlregulationen des Immunsystems und damit zu einem Anstieg von: allergischen Erkrankungen, Autoimmunerkrankungen, entzündlichen Darmerkrankungen, Atherosklerose, Depressionen mit entzündlicher Komponente, möglicherweise, Alzheimer und Parkinson. Die Hygienehypothese wird in einen evolutionären Kontext gestellt: Der menschliche Organismus ist an eine Umwelt angepasst, in der dauerhafte mikrobielle Stimulation normal war. Das moderne Mikroben-Defizit erzeugt evolutionär unpassende Immunreaktionen. Der Autor verbindet bei seinem Denkweg mikrobiologische Evolutionsgeschichte, Immunologie, Epidemiologie, klinische Beispiele aus vielen Organsystemen, therapeutische Perspektiven. Sprache: Englisch Gewicht in Gramm: 855.…

Zustand: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher | Keine Beschreibung verfügbar.

Paperback. Zustand: Brand New. 1st edition. 608 pages. 9.75x6.75x1.25 inches. In Stock.

Taschenbuch. Zustand: Neu. Evolution, Biodiversity and a Reassessment of the Hygiene Hypothesis | Graham A. W. Rook (u. a.) | Taschenbuch | Progress in Inflammation Research | x | Englisch | 2023 | Springer | EAN 9783030910532 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. …

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This edited collection of 12 chapters by research workers from a wide range of disciplines resolves the confusion that currently surrounds the 'hygiene hypothesis' by considering the human need for exposure to microorganisms from an evolutionary point of view. The book explains why we evolved a requirement for exposure to microbiota from our mothers, from other people, and from the natural environment. It also explains the physiological roles of these exposures, what goes wrong when the exposures are distorted and how human lifestyles and activities, including degradation of the natural environment, are leading to this distortion. Particular attention is given to the range of pathologies associated with inappropriate microbial exposures and inappropriate colonization, including immunoregulatory problems such as allergies and autoimmunity, metabolic problems such as obesity and diabetes, and problems of central nervous system function and neurodegeneration. This book is of profound relevance to most medical disciplines, but also to those concerned with preserving the natural environment and with developing healthier urbanisation.…

Zustand: New. In English.

Zustand: gut. 2009. The Hygiene Hypothesis and Darwinian Medicine (Progress in Inflammation Research) In deutscher Sprache. pages.

Hardcover. Zustand: Brand New. 424 pages. 9.25x6.10x0.87 inches. In Stock.

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Man has moved rapidly from the hunter-gatherer environment to the living conditions of industrialised countries. The hygiene hypothesis suggests that the resulting reduced exposure to micro-organisms has led to disordered regulation of the immune system, and hence to increases in certain chronic inflammatory disorders, like allergic disorders, autoimmunity, inflammatory bowel disease, atherosclerosis, depression, some cancers and perhaps Alzheimer and Parkinson. This book discusses the evidence for and against in the context of Darwinian medicine, which uses knowledge of evolution to cast light on human diseases. The approach is interdisciplinary, looking at man's microbiological history, at the biology of the effects of microorganisms on the immune system, and at the implications for chronic inflammatory disorders in multiple organ systems. Finally, the authors describe progress in the exploitation of microorganisms or their components as novel prophylactics and treatments.…

Hardcover. Zustand: Brand New. 1st edition. 317 pages. 9.21x6.61x0.94 inches. In Stock.

Zustand: New. This book takes an interdisciplinary approach in discussing the evidence for and against the so-called 'hygiene hypothesis'. It does so in the context of Darwinian medicine, which deploys our knowledge of evolution in an effort to cast light on human diseases. Series: Progress in Inflammation Research. Num Pages: 308 pages, 10 black & white tables, biography. BIC Classification: MJCJ; MJCM; MMFM. Category: (P) Professional & Vocational. Dimension: 244 x 170 x 23. Weight in Grams: 885. . 2009. Hardback. . . . . Books ship from the US and Ireland.…

Rotterdam, Uitgeverij 010, 1984. bPaperback / Softcover. 25 x 17,5 cm. Met illustraties in z/w. 64 pag. GOED EXEMPLAAR [.

Zustand: New.