Urban laszlo (19 Ergebnisse)

Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Hardcover. Zustand: Very Good. Hit and Lead Profiling: Identification and Optimization of Drug-like Molecules by Bernard Faller & Laszlo Urban eds.Includes inscription to 'Humphrey' by Laszlo UrbanMethods and Principles in Medicinal Chemistry, Vol. 43The only reference on current methods to generate pharmacokinetic and safety profiles of drug candidates, as well as how they must be balanced against one other for the best selection of candidates for further development. Following a brief introduction to the necessities of filtering and risk assessment of potential new drug molecules before actual drug development, the two equally important aspects of pharmacological (ADME) and safety (toxicity) profiling are covered in sep.…

Zustand: New. In English.

Zustand: Used. pp. 410.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The research field of somatosensory processing in mammals has experienced revolutionary changes in recent years. Accumulation of basic and clinical data has greatly accelerated, and new phenomena have emerged. With the aid of new, refined methods, molecular and cellular changes have been described, underlying the signal transduction-transmission between the internal/external environment and the central nervous system have been described. The discovery of the interaction between the nervous and the immune system has, for example changed our view on the development of inflammatory diseases, while the cloning of genes encoding different trophic factors has boosted studies revealing profound changes in the regeneration of neurons, and induction of changes in phenotype. The study of the pre-and postsynaptic modulation of transmitter release, and the examination of the combined effects of amino acid and peptide transmitters has become recently possible by using cultured cell lines and in vitro techniques. Although it is in embryonic state, computational properties of single DRG cells under normal and pathological conditions are being investigated. Results soon or later will have a great impact on pain research and consequently ultimately in clinical pain management. This brief introduction indicates how our knowledge of the somatosensory system has increased dramatically recently. However, many investigators cultivate only a very specific field in the growing area of somatosensory research and find it difficult to integrate a more universal knowledge of their work.…

Zustand: New. pp. 336.

Zustand: Used. pp. 410.

Taschenbuch. Zustand: Neu. Cellular Mechanisms of Sensory Processing | The Somatosensory System | Laszlo Urban | Taschenbuch | xi | Englisch | 2011 | Springer | EAN 9783642787645 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. …

Paperback. Zustand: Brand New. reprint edition. 513 pages. 9.25x6.10x1.30 inches. In Stock.

Zustand: New. In English.

Zustand: New. In English.

Zustand: New. In English.

Zustand: New. pp. 616.

Gebunden. Zustand: New. Laszlo Urban received his MD and PhD in neurophysiology/neuropharmacology in Hungary, and was visiting professor at Duke University between 1987 and 1989. He is currently global head of Preclinical Safety Profiling at the Novartis Institutes for Biomedical .

Hardcover. Zustand: Brand New. 1st edition. 400 pages. 10.00x7.00x0.50 inches. In Stock.

Hardcover. Zustand: Brand New. 596 pages. 9.50x6.50x1.50 inches. In Stock.

Zustand: New. Provides information on drug side effects and their mitigation strategy during drug discovery, as well as guidance for risk assessment and evidence-based toxicology. Editor(s): Xu, Jinghai J.; Urban, Laszlo. Num Pages: 404 pages, 84 b/w illus. 35 tables. BIC Classification: MMG. Category: (P) Professional & Vocational. Dimension: 258 x 189 x 27. Weight in Grams: 1010. . 2010. Illustrated. hardcover. . . . . Books ship from the US and Ireland. …

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - According to the Institute of Medicine (IOM) and U.S. Food and Drug Administration (FDA), 'developing new scientific approaches to detecting, understanding, predicting and preventing adverse events' was a critical path to the future of drug safety. This book brings together a collection of state-of-the-art chapters, written by experts in the drug safety field. It provides information on the present knowledge of drug side effects and their mitigation strategy during drug discovery, gives guidance for risk assessment and promotes evidence-based toxicology. Each specific area of toxicology relevant for drug discovery is discussed in detail, including theory, experimental approaches and data interpretation supported by comprehensive up-to-date references. Many chapters provide fascinating case studies, which are of general interest for those who have basic science training and are interested in how chemicals interact with the human body.…

Zustand: New. pp. 528.