simic michael g (6 Ergebnisse)

Hardcover. Zustand: Very Good. Zustand des Schutzumschlags: Good. 659 pp., diagrams, bibliography, index. wear & small tears to dust jacket, owner's address stamp inside front & back covers & on FFEP. The material presented in this book deals with basic mechanisms of free radical reactions in autoxidation processes and anitoxidant suppression of autoxidation of foods, biochemical models and biologi­cal systems. Autoxidation in foods and corresponding biological effects are usually approached separately although recent mechanistic developments in the biochemistry and free radical chemistry of per­ oxides and their precursors tend to bring these two fields closer. Apparent ability of antioxidants in diets to reduce the inci­dence of cancer has resulted in scrutiny of autoxidized products and their precursors as possibly toxic, mutagenic and carcinogenic agents. Mechanisms of any of these effects have been barely ad­ dressed. Yet we know now that free radicals, as esoteric as they were only a few decades ago, are being discovered in foods, biochem­ical and biological systems and do play a role in the above-mentioned causalities. The purpose of the Workshop and the resulting book was to give a unifying approach towards study of beneficial and deleterious effects of autoxidation, based on rigorous scientific considerations. It is our hope that the material presented in this book will not only provide a review of the "state of the art" of autoxidation and anti­ oxidants, but also reflect the interaction which occurred during the Workshop between workers using model systems, and food and biological systems.

Zustand: New. In.

Zustand: Good. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. In good all round condition. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,1400grams, ISBN:030640561X.

Taschenbuch. Zustand: Neu. Mechanisms of DNA Damage and Repair | Implications for Carcinogenesis and Risk Assessment | Michael G. Simic (u. a.) | Taschenbuch | xv | Englisch | 2012 | Springer | EAN 9781461594642 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.

Paperback. Zustand: Brand New. reprint edition. 594 pages. 9.45x6.61x1.35 inches. In Stock.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book is based on the papers presented at the conference on 'Mecha nisms of DNA Damage and Repair: Implications for Carcinogenesis and Risk Assessment,' held at the National Bureau of Standards on June 2-7, 1985, This volume deals with mechanisms of DNA damage and repair at the molecular level; consequences of unrepaired or misrepaired damage, with major emphasis on carcinogenesis; drugs which bind selectively to altered and potentially damaging DNA sequences; and potential utilization of DNA damage as an endpoint for assessing risks of UV light, ionizing radiations, chemicals, drugs, and hazardous agents in foods. Because the induction of mutations by radiation and genotoxic chemicals has been observed to follow one-hit kinetics in some instances, it is generally assumed that any level of exposure to a DNA-damaging agent may increase the risk of genetic disease or cancer in an exposed population. At the same time, however, there is evidence that although the DNA of living cells is continually damaged by natural background radiation, free radicals, and other naturally occurring processes, most of the damage is normally repaired.