Robert i nicholson (14 Ergebnisse)

Hardcover. Zustand: New.

Hardcover. Zustand: Very Good. No Dust Jacket. This text reviews the latest ideas in tumor biology, explains the pharmacologic basis of the agents used, and discusses how they are applied in clinical practice. Part One presents an overview of the clinical importance of endocrine therapy, and describes the applications of the principal classes of drugs, including antiestrogens, aromatase inhibitors, progestins, and progesterone receptor antagonists. This section also discusses ovarian ablation. Part Two deals with the biological aspects of endocrine therapies, and relates current understanding of tumor biology and the pharmacologic basis of hormonal agents to their clinical applications. Among the topics covered are resistance and sensitivity to therapy. Part Three outlines future strategies, in particular the use of combination endocrine therapy, adjuvant growth factor therapy and the use of anti-invasive agents. This text is essential for oncologists and pharmacologists alike. Clean Copy.…

Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Hardcover. Zustand: Brand New. 1st edition. 296 pages. 9.75x7.50x0.75 inches. In Stock.

Zustand: New. In English.

Zustand: New. In English.

Hardcover. Zustand: Brand New. 230 pages. 9.25x6.25x1.00 inches. In Stock.

Zustand: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher | One of the main causes of failure in the treatment of breast cancer is the intrinsic presence of, or development of, drug resistance by the cancer cells. Recent studies on the mechanisms of cancer drug resistance have yielded important information highlighting both how tumour cells may escape these therapeutic constraints and that drug resistance may further impinge on tumour cell functions that may ultimately promote an adverse cell phenotype. New targets have been identified with potential therapeutic applications in resistant breast cancer leading to the subsequent evaluation of inhibitors of these targets in preclinical studies. Importantly, there is increasing evidence from such studies demonstrating the benefit of novel combination strategies as potential avenues for future drug regimens. Written by experts in the subject area, this book covers the molecular details and functional consequences of endocrine resistance in breast cancer with particular emphasis on the future applications of novel drug combinations that may be utilized to circumvent resistance and improve anti-tumour effects. This book represents a timely publication in the field of breast cancer research, providing current knowledge in the area of drug resistance and will be important reading material for clinicians and researchers alike.…

Hardcover. Zustand: Brand New. 1st edition. 198 pages. 9.50x6.25x0.25 inches. In Stock.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - One of the main causes of failure in the treatment of breast cancer is the intrinsic presence of, or development of, drug resistance by the cancer cells. Recent studies on the mechanisms of cancer drug resistance have yielded important information highlighting both how tumour cells may escape these therapeutic constraints and that drug resistance may further impinge on tumour cell functions that may ultimately promote an adverse cell phenotype. New targets have been identified with potential therapeutic applications in resistant breast cancer leading to the subsequent evaluation of inhibitors of these targets in preclinical studies. Importantly, there is increasing evidence from such studies demonstrating the benefit of novel combination strategies as potential avenues for future drug regimens.Written by experts in the subject area, this book covers the molecular details and functional consequences of endocrine resistance in breast cancer with particular emphasis on the future applications of novel drug combinations that may be utilized to circumvent resistance and improve anti-tumour effects. This book represents a timely publication in the field of breast cancer research, providing current knowledge in the area of drug resistance and will be important reading material for clinicians and researchers alike.…

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - One of the main causes of failure in the treatment of breast cancer is the intrinsic presence of, or development of, drug resistance by the cancer cells. Recent studies on the mechanisms of cancer drug resistance have yielded important information highlighting both how tumour cells may escape these therapeutic constraints and that drug resistance may further impinge on tumour cell functions that may ultimately promote an adverse cell phenotype. New targets have been identified with potential therapeutic applications in resistant breast cancer leading to the subsequent evaluation of inhibitors of these targets in preclinical studies. Importantly, there is increasing evidence from such studies demonstrating the benefit of novel combination strategies as potential avenues for future drug regimens.Written by experts in the subject area, this book covers the molecular details and functional consequences of endocrine resistance in breast cancer with particular emphasis on the future applications of novel drug combinations that may be utilized to circumvent resistance and improve anti-tumour effects. This book represents a timely publication in the field of breast cancer research, providing current knowledge in the area of drug resistance and will be important reading material for clinicians and researchers alike.…

Hardcover. Zustand: Good. Zustand des Schutzumschlags: Very Good. Limited Edition. This wondeful set of nine volumes are all in really good condition, all come with their beautiful dust jackets. Blue cloth, hardbacks with gorgeous gilt title impressions on the spine. Normal wear and marks apply consistent with use and age. Some finger marks to edge of papers from use, mild toning, light spotting to fore-edge to volume two. Limited RSPB Edition 5000 copies. Numerous illustrations by many artists, including Robert Gilmour, Peter Scott etc, and many in colour. . Volume I. Ostrich to Ducks has 722 pages. Volume II. Hawks to Bustards has 695 pages. Volume III. Waders to Gulls has 911 pages plus egg plate pages. Volume IV. Terns to Woodpeckers has 960 pages. Volume V. Tyrant Flycatchers to Thrushes has 1063 pages plus egg plate pages. Volume VI. Warblers has 728 pages. Volume VII. Flycatchers to Shikes has 577 pages plus egg plate pages. Volume VIII. Crows to Finches has 899 pages plus egg plate pages. Volume IX. Buntings and New World Warblers has 488 pages plus egg plate pages. This entire and authoritative work of reference has been planned to take account of the great advances that have been made in ornithological knowledge since the publication of the "Handbook of British Birds" (1938-41) which for many years provided the basis on which ornithological research in the UK was built. Ornithologists now work on a wider geographical basis, and these handbooks covers the whole of the Western Paleartic, which includes all Europe together with the Middle East to Turkey, Iraq, and Jordon, and Africa south to about 19 degrees North. Within the nine volumes are: Descriptions of over 770 species of birds, illustrations of each species in the form of specially commissioned colour plates. Colour Plates of eggs, black and white illustrations and many text figures showing such features as display postures, flight views, voice sonagrams, and melograms and annual cycles. A bibliography and indexes in each volume. This complete set is an indispensible work of reference, both for the professional scientist and for the ever growing body of amatuer ornithologists whose range of interests is expanding every year. Please note these books are comprehensive and are large volumes and when packaged together are packaged in a proper box/case to ship, therefore postage/shipping may increase from listed price depending on final destination. Please do contact to get a shipping quotation. An amazing collection of nine books that have been put together by so many talented individuals. The perfect reference for anyone who has an interest in birds.…