Rigers bakiu (5 Ergebnisse)

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Document from the year 2016 in the subject Biology - Evolution, grade: -, Agricultural University of Tirana, language: English, abstract: G protein-coupled receptors (GPCRs) are members of a large protein family that share common structural motifs, including seven transmembrane helices, and play pivotal roles in cell-to-cell communications and in the regulation of cell functions. GPR103 is an orphan GPCR that shows similarities with orexin, neuropeptide FF, and cholecystokinin receptors.In humans, 26RFa/QRFP has been found to be an endogenous ligand for the orphan receptor, GPR103 and it is one of the RFamide peptides, which have been shown to exert important neuroendocrine, behavioural, sensory and autonomic functions.All the information we have till know couldn' be available if we didn't know the evolution of this important proteins and the relative interactions, which were discovered recently to be important for the regulation of locomotor activity, sleep and these neuropeptides and receptors exert neuroprotective effect in Alzheimer's Disease.Anyway, there is a long way to be walked on, because there is a need of additional information, while studing the molecular evolution of these proteins and peptides.What is the Molecular Evolution In the First chapter the readers can find all about this branch of science and the problems this branch had overcomed in order to bring to the scientific community the molecularisation of the evolution concepts.In the following chapter to the readers is presented a descriptive overview of G-proteins and G-protein coupled receptor.In the other chapters it is also presented 26RFA/QRFP and pyroglutamylated RFamide peptide receptor (QRFPR) molecular evolution, where it is described the molecular phylogeny and the functional implication. It is even shown the unique study regarding the presence on natural selection (positive or negative selection) during the evolution of QRFPRs in mammals and fish species.In the end of the book are shown the recent important finding regarding the function and the role of QRFP and its receptor, together with the experimental approach applied to zebrafish and rodents.Anyway, it is imperative to mention that all the available knowledge from experiments to these animals can be useful for the curation of disorders and other deseases like Alzheimer's Disease, only if we could understand well their molecular evolution.…

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Document from the year 2016 in the subject Environmental Sciences, Agricultural University of Tirana (Agricultural University of Tirana), language: English, abstract: Definitions of Marine protected areas (MPAs) vary from exclusionary to inclusionary. A recently revised IUCN definition of what constitutes a protected area (PA) emphasizes the conservation purpose of geographical space. ''Conservation'' is defined as the in situ maintenance of ecosystems and natural and semi-natural habitats and of viable populations of species in their natural surroundings. Prohibition or restriction of activities within a PA is usually part of the in situ maintenance. For marine sites this engenders unique management opportunities and challenges.Temporal trends indicate that overexploitation and habitat loss have been the main human drivers of historical changes in Mediterranean biodiversity. At present, habitat loss and degradation, followed by fishing impacts, pollution, climate change, eutrophication, and the establishment of alien species are the most important threats and affect the greatest number of taxonomic groups. All these impacts are expected to grow in importance in the future, especially climate change and habitat degradation. Marine experts and conservationists see great hope in the opportunities provided by MPAs to counter threats to marine ecosystems. In this book, the effects of the MPAs are illustrated based on detailed analyses of the recent case studies of Mediterranean charismatic species, like monk seal, dolphins, groupers, seagrass meadows and birds. This book examines the use of MPAs as a way to restore and maintain healthy marine environments by contributing to the overall protection of critical marine habitats and resources in Mediterranean. It suggest the best way to manage the existing ones after providing case studies showing the actual situation of them and how to establish the future MPAs in the Mediterranean. This book is the precious instrument, full of conservation strategies based on MPA networks aimed at enhancing resilience and it may be the most effective tool to limit the negative impacts of the complex suites of threats on marine ecosystems under future scenarios of frequent and/or persistent disturbance.…

Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Zustand: Used. pp. 103.

Zustand: Used. pp. 103.