Richard morphy (16 Ergebnisse)

Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Zustand: New. pp. xi + 295 Illus.

Zustand: New. pp. 394.

Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Zustand: New. This resource provides an integrated and comprehensive overview ofmodern approaches to drug lead discovery. Each chapter in this bookreviews the theoretical background and application of a keytechnology in drug discovery, complemented by relevant casestudies. Num Pages: 296 pages, Illustrations. BIC Classification: MBGR1. Category: (P) Professional & Vocational. Dimension: 243 x 163 x 22. Weight in Grams: 570. . 2010. 1st Edition. Hardcover. . . . . Books ship from the US and Ireland. …

Gebunden. Zustand: New. ZORAN RANKOVIC is a Senior Research Fellow and Associate Director in Medicinal Chemistry at Schering-Plough Research Institute, UK. He received his PhD in organic chemistry from the University of Leeds (UK) before starting his medicinal chemistry career in .

Buch. Zustand: Neu. Neuware - An integrated overview of modern approaches to lead discoveryLead generation is increasingly seen as a distinct and success-determining phase of the drug discovery process. Over recent years, there have been major advances in the understanding of what constitutes a good lead compound and how to improve the chances of finding such a compound. Written by leading scientists and established opinion leaders from industry and academia, this book provides an authoritative overview of the field, as well as the theory, practice, and scope, of the principal Lead Generation Approaches in Drug Discovery, including:\* The evolution of the lead discovery process, key concepts, current challenges, and future directions\* Strategies and technologies driving the high-throughput screening (HTS) approach to lead discovery, including the shifting paradigms in the design of compound collections and best practice in the hit confirmation process\* Knowledge-based in silico or 'virtual' screening\* Theory and practice of the fragment-based approach to lead discovery\* The opportunities and challenges presented by multi-target drug discovery (MTDD)\* De novo design of lead compounds and new approaches to estimating the synthetic accessibility of de novo-designed molecules\* The impact of natural products on drug discovery, and potential of natural product-like compounds for exploring regions of biologically relevant chemical space\* Using early screening of hits and leads for metabolic, pharmacokinetic, and toxicological liabilities to reduce attrition during the later phases of drug discovery\* The utility of parallel synthesis and purification in lead discoveryWith each topic supported by numerous case studies, this is indispensable reading for researchers in industry and academia who wish to keep up to date with the latest strategies and approaches in drug discovery.…

Paperback. Zustand: Brand New. 444 pages. 9.21x6.30x1.02 inches. In Stock.

Zustand: New. In English.

Gebunden. Zustand: New. This is the first book to pull together studies and reviews from cutting edge authors who work in the emerging and exciting field of multi-targeted drug discovery.&Uumlber den AutorrnrnRichard Morphy gained his BSc (1995) and PhD (1989 sup.

Paperback. Zustand: Brand New. 444 pages. 9.21x6.30x1.02 inches. In Stock.

Buch. Zustand: Neu. Neuware - Multi-target drug discovery (MTDD) is an emerging area of increasing interest to the drug discovery community. Drugs that modulate several targets have the potential for an improved balance of efficacy and safety compared to single targets agents. Although there are a number of marketed drugs that are thought to derive their therapeutic benefit by virtue of interacting with multiple targets, the majority of these were discovered accidentally. Written by world renowned experts, this is the first book to gather together knowledge and experiences of the rational discovery of multi-target drugs. It describes the current state of the art, the achievements and the challenges of the field and importantly the lessons learned by researchers to date and their application to future MTDD.…