Randy horwitz (10 Ergebnisse)
Sprache: Englisch
Verlag: Oxford University Press, 2010
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Sprache: Englisch
Verlag: Oxford University Press, 2010
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hardcover. Zustand: Very Good. May have light to moderate shelf wear and/or a remainder mark. Complete. Clean pages.
Sprache: Englisch
Verlag: Oxford University Press, 2011
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Zustand: Good. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. In good all round condition. Dust jacket in good condition. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,700grams, ISBN:9780195311211.
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Zustand: New. In.
Sprache: Englisch
Verlag: OXFORD UNIV PR, 2010
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hardcover. Zustand: Gut. 352 Seiten; 9780195311211.3 Gewicht in Gramm: 1.
Sprache: Englisch
Verlag: Oxford University Press Okt 2010, 2010
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Buch. Zustand: Neu. Neuware - In this volume, the authors describe a rational and evidence-based approach to the integrative therapy of rheumatologic, allergic, and autoimmune disorders, integrating the principles of alternative and complementary therapies into the principles and practice of conventional medical therapy. The aut…hors examine what works and what doesn't and offer practical guidelines for physicians for incorporating integrative medicine into their practice and advising patients on reasonable and effective therapies. The text discusses areas of controversy and identifies areas of uncertainty where future research is needed. Chapters cite the best available evidence for both safety and efficacy of all therapies discussed. Information will be presented in accessible and easy-to-read formats, including clinical pearls, case histories, and key points, with a second text color for highlighting key information.
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Zustand: Hervorragend. Zustand: Hervorragend | Sprache: Englisch | Produktart: Bücher | Abstract:The purpose of this study was to understand the control of synthesis of Tdt at a molecular level, using a murine pre B-cell line inducible for the enzyme. FLEl-4, an Abelson virus transformed fetal liver cell line, when treated with…dibutyryl cAMP and caffeine (or other phosphodiesterase inhibitors), shows a three- to tenfold induction of Tdt, as measured by immunoprecipitation of pulse labelled enzyme, activity assays, and steady-state northern blot. The study also revealed Tdt expression (mRNA induction) by a group of agents which inhibit DNA synthesis by various mechanisms. This finding implies that Tdt expression is unlinked to clonal proliferation of pre-B cells, and suggests a multistage model for B-cell differentiation and the generation of immunoglobulin somatic variation. At a molecular level, the agents that induce Tdt were also shown to increase intracellular cAMP levels shortly before Tdt transcription. Finally, an analysis of histone phosphorylation patterns in induced cells reveal a marked enhancement of histone HI phosphorylation, a finding which may be related to the induction event. Dissertation Discovery Company and the University of Florida are dedicated to making scholarly works more discoverable and accessible throughout the world. This dissertation, "The Regulation of Expression of Terminal Deoxynucleotidyl Transferase in an Inducible Murine Pre-B Cell Line" by Randy Jonathan Horwitz, was obtained from the University of Florida and is being sold with permission from the author. A free digital copy of this work may also be found in the university's institutional repository, the IR@UF. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation.
Sprache: Englisch
Verlag: OUP USA, 2010
- Hardcover
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Zustand: New. "In this volume in the series, the authors describe a rational and evidence-based approach to the integrative therapy of rheumatologic, allergic, and autoimmune disorders, integrating the principles of alternative and complementary therapies into the principles and practice of conventional medical therapy"--Provide…d by publisher. Series: Weil Integrative Medicine Library. Num Pages: 376 pages, 50 illus. BIC Classification: MJCM; MJCM1; MJM; MX. Category: (P) Professional & Vocational. Dimension: 242 x 162 x 20. Weight in Grams: 604. . 2010. Illustrated. hardcover. . . . . Books ship from the US and Ireland.
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Zustand: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher | Abstract:The purpose of this study was to understand the control of synthesis of Tdt at a molecular level, using a murine pre B-cell line inducible for the enzyme. FLEl-4, an Abelson virus transformed fetal liver cell line, when treated with dibutyry…l cAMP and caffeine (or other phosphodiesterase inhibitors), shows a three- to tenfold induction of Tdt, as measured by immunoprecipitation of pulse labelled enzyme, activity assays, and steady-state northern blot. The study also revealed Tdt expression (mRNA induction) by a group of agents which inhibit DNA synthesis by various mechanisms. This finding implies that Tdt expression is unlinked to clonal proliferation of pre-B cells, and suggests a multistage model for B-cell differentiation and the generation of immunoglobulin somatic variation. At a molecular level, the agents that induce Tdt were also shown to increase intracellular cAMP levels shortly before Tdt transcription. Finally, an analysis of histone phosphorylation patterns in induced cells reveal a marked enhancement of histone HI phosphorylation, a finding which may be related to the induction event. Dissertation Discovery Company and the University of Florida are dedicated to making scholarly works more discoverable and accessible throughout the world. This dissertation, "The Regulation of Expression of Terminal Deoxynucleotidyl Transferase in an Inducible Murine Pre-B Cell Line" by Randy Jonathan Horwitz, was obtained from the University of Florida and is being sold with permission from the author. A free digital copy of this work may also be found in the university's institutional repository, the IR@UF. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation.
