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Sprache: Englisch
Verlag: Plenum Publishing Corporation, 1973
ISBN 10: 0306377918 ISBN 13: 9780306377914
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Sprache: Englisch
Verlag: New York : Academy of Sciences, 1971
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Sprache: Englisch
Verlag: Springer Berlin Heidelberg, 2012
ISBN 10: 3662027666 ISBN 13: 9783662027660
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In den WarenkorbZustand: New. There is much evidence to suggest that prostaglandins may have a physiological role to play in the control of thyroid gland metabolism, although the precise nature of this role remains to be defined. Prostaglandins have been found in normal thyroid tissue, .
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Sprache: Englisch
Verlag: Springer Berlin Heidelberg, 2012
ISBN 10: 3662027666 ISBN 13: 9783662027660
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Evidence accumulated over the past decade show that gonadal steroid hormones participate in an important way in the physiological and pa thophysiological regulation of the cardiovascular system. The hor monal profile appears to put males at a disadvantage biologically in terms of cardiovascular diseases. The incidence of hypertension is higher in men than in pre-monopausal women indicating an influence of gender on the hypertensive disease process. Males and females have equivalent cholesterol levels until puberty but males suffer an ex ponential increase in heart disease in their forties, while the female rise does not start until a decade later, after menopause. Animal and human studies provided ample evidence, that estrogens lower the levels of low density lipoproteins and keep high density lipoproteins elevated. These changes may be advantageous in the prevention of heart diesease. Co ronary artery atherosclerosis has been shown to be more pronounced in ovarectomized female monkeys as in intact females. Androgen, con versely, lowers the high density lipoproteins and elevates low density lipoproteins. Regarding blood pressure, it is well established that hypertension is more severe or develops more rapidly in male than fe male rats in several genetic forms of hypertension, and that gonadal steroid hormones are probably playing an important role in explaining this observation. Risk factors of human hypertension and coronary heart dies ease include menopause and ovarectomy.
Taschenbuch. Zustand: Neu. The Prostaglandins | Volume 3 | Peter Ramwell | Taschenbuch | xii | Englisch | 2012 | Humana | EAN 9781461580577 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
Sprache: Englisch
Verlag: Springer, Humana Nov 2012, 2012
ISBN 10: 1461580579 ISBN 13: 9781461580577
Anbieter: AHA-BUCH GmbH, Einbeck, Deutschland
Taschenbuch. Zustand: Neu. Neuware - 1 Gas Chromatography-Mass Spectrometry of Prostaglandins.- I. Introduction.- II. Mass Spectrometry Systems for Prostaglandin Analysis.- III. Methods of Extraction and Chromatography.- IV. Biological Applications.- V. References.- Note Added in Proof.- 2 Prostaglandin Biosynthesis and Metabolism as Measured by Radioimmunoassay.- I. Introduction.- II. Serological Specificities of the Prostaglandin Immune Systems.- III. Prostaglandin Synthetase.- IV. Prostaglandin E 9-Ketoreductases.- V. 15-Hydroxyprostaglandin Dehydrogenases.- VI. Prostaglandin 13-Reductase.- VII. PGE Dehydrase, PGA Isomerase, and PGC Isomerase.- VIII. Regulation of PGE and PGF Levels.- IX. References.- Note Added in Proof.- 3 The Endocrine System: Interaction of Prostaglandins with Adenylyl Cyclase-Cyclic AMP Systems.- I. Introduction.- II. Thyroid.- III. Pituitary.- IV. Pancreas.- V. Adrenal.- VI. Ovaries.- VII. References.- 4 Induction of Labor with Prostaglandins.- I. Historical Background.- II. Induction of Labor with Intravenous Prostaglandins.- III. Other Routes of Administration.- IV. Conclusions.- V. References.- 5 Cardiovascular Responses to the Prostaglandin Precursors.- I. Introduction.- II. Blood Pressure.- III. Cardiac Effects.- IV. Renal Circulation.- V. Pulmonary Circulation.- VI. Other Regional Circulations.- VII. Platelets 141 VIII Summary.- IX. References.- 6 Role of Prostaglandins in Fever and Temperature Regulation.- I. Introduction.- A. Temperature Regulation B. Fever 148.- II. Role of PGs in Fever.- III. PG Synthesis in Brain during Fever.- IV. Difficulties with the PG Hypothesis.- V. PGs in Normal Temperature Regulation.- VI. Summary of the Existing Evidence.- VII. Addendum.- VIII. References.- 7 Prostaglandins and the Lung.- I. Introduction.- II. Prostaglandin Content andSynthesis in the Lung.- III. Catabolism and Uptake of Prostaglandins in the Lung.- IV. Release of Prostaglandins from the Lung.- V. Bronchopulmonary Effects of Prostaglandins.- VII. Summary and Conclusions.- VIII. References.- Note Added in Proof.- 8 Prostaglandins and the Digestive System.- I. Introduction.- II. Salivary Glands.- III. Esophagus.- IV. Stomach.- VI. Bile and Pancreatic Secretion.- VII. Cytoprotection by Prostaglandins.- VIII. References.- 9 Prostaglandins and Renal Function, or 'A Trip down the Rabbit Hole'.- I. Introduction.- II. Prostaglandin Synthesis and Metabolism.- III. Role of Prostaglandins in the Control of Renal Blood Flow.- IV. Role of Prostaglandins in Salt and Water Homeostasis.- V. Conclusion.- VI. References.- Note Added in Proof.- 10 Prostaglandins and Cancer.- I. Introduction.- II. Prostaglandin Synthesis by Tumors and Its Effects on Tumor Cell Replication.- III. Prostaglandins, Bone Resorption, and Hypercalcemia.- IV. Conclusions.- V. References.
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Taschenbuch. Zustand: Neu. Neuware - There is much evidence to suggest that prostaglandins may have a physiological role to play in the control of thyroid gland metabolism, although the precise nature of this role remains to be defined. Prostaglandins have been found in normal thyroid tissue, and there is evidence of increased levels in some, but not all, cases of medullary carcinoma of the thyroid. which may account for the associated diarrhea. Exogenous prostaglandins, like TSH, bind to thyroid plasma mem branes, stimulate the adenylate cyclase-cyclic AMP system, thyroid hormone secretion, iodide organification, colloid droplet formation, glucose oxidation, and 32p incorporation into phospholipids. Prosta glandins of the E series are the most potent, although their maximal effects are generally less than the maximal effects of TSH. The interrelationships existing between TSH and prostaglandins have been the subject of intensive investigation, but as yet no one uni fying concept has emerged. TSH and prostaglandins have been shown to occupy different receptors on the thyroid plasma membrane. Al though TSH can increase intracellular prostaglandin levels, probably as a result of increased synthesis, prostaglandins do not appear to be essential intermediates in TSH action on adenylate cyclase. The pos sibility that prostaglandins are part of a negative feedback system con trolling TSH action is, as yet, a tentative hypothesis, and further work will be required to unravel the interrelationships between these sub stances that now appear to be far more complex than has been envisaged thus far.
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Taschenbuch. Zustand: Neu. Prostaglandins in Cellular Biology | Proceedings of the ALZA Conference on Prostaglandins in Cellular Biology and the Inflammatory Process held in Carmel, California, October 24-26, 1971 | Peter Ramwell | Taschenbuch | xi | Englisch | 2012 | Springer | EAN 9781468428469 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
Sprache: Englisch
Verlag: Springer, Humana Nov 2012, 2012
ISBN 10: 1461580579 ISBN 13: 9781461580577
Anbieter: Books-by-Floh, Paderborn, Deutschland
Taschenbuch. Zustand: Neu. Neuware -1 Gas Chromatography-Mass Spectrometry of Prostaglandins.- I. Introduction.- II. Mass Spectrometry Systems for Prostaglandin Analysis.- III. Methods of Extraction and Chromatography.- IV. Biological Applications.- V. References.- Note Added in Proof.- 2 Prostaglandin Biosynthesis and Metabolism as Measured by Radioimmunoassay.- I. Introduction.- II. Serological Specificities of the Prostaglandin Immune Systems.- III. Prostaglandin Synthetase.- IV. Prostaglandin E 9-Ketoreductases.- V. 15-Hydroxyprostaglandin Dehydrogenases.- VI. Prostaglandin 13-Reductase.- VII. PGE Dehydrase, PGA Isomerase, and PGC Isomerase.- VIII. Regulation of PGE and PGF Levels.- IX. References.- Note Added in Proof.- 3 The Endocrine System: Interaction of Prostaglandins with Adenylyl Cyclase-Cyclic AMP Systems.- I. Introduction.- II. Thyroid.- III. Pituitary.- IV. Pancreas.- V. Adrenal.- VI. Ovaries.- VII. References.- 4 Induction of Labor with Prostaglandins.- I. Historical Background.- II. Induction of Labor with Intravenous Prostaglandins.- III. Other Routes of Administration.- IV. Conclusions.- V. References.- 5 Cardiovascular Responses to the Prostaglandin Precursors.- I. Introduction.- II. Blood Pressure.- III. Cardiac Effects.- IV. Renal Circulation.- V. Pulmonary Circulation.- VI. Other Regional Circulations.- VII. Platelets 141 VIII Summary.- IX. References.- 6 Role of Prostaglandins in Fever and Temperature Regulation.- I. Introduction.- A. Temperature Regulation B. Fever 148.- II. Role of PGs in Fever.- III. PG Synthesis in Brain during Fever.- IV. Difficulties with the PG Hypothesis.- V. PGs in Normal Temperature Regulation.- VI. Summary of the Existing Evidence.- VII. Addendum.- VIII. References.- 7 Prostaglandins and the Lung.- I. Introduction.- II. Prostaglandin Content andSynthesis in the Lung.- III. Catabolism and Uptake of Prostaglandins in the Lung.- IV. Release of Prostaglandins from the Lung.- V. Bronchopulmonary Effects of Prostaglandins.- VII. Summary and Conclusions.- VIII. References.- Note Added in Proof.- 8 Prostaglandins and the Digestive System.- I. Introduction.- II. Salivary Glands.- III. Esophagus.- IV. Stomach.- VI. Bile and Pancreatic Secretion.- VII. Cytoprotection by Prostaglandins.- VIII. References.- 9 Prostaglandins and Renal Function, or 'A Trip down the Rabbit Hole'.- I. Introduction.- II. Prostaglandin Synthesis and Metabolism.- III. Role of Prostaglandins in the Control of Renal Blood Flow.- IV. Role of Prostaglandins in Salt and Water Homeostasis.- V. Conclusion.- VI. References.- Note Added in Proof.- 10 Prostaglandins and Cancer.- I. Introduction.- II. Prostaglandin Synthesis by Tumors and Its Effects on Tumor Cell Replication.- III. Prostaglandins, Bone Resorption, and Hypercalcemia.- IV. Conclusions.- V. References. 376 pp. Englisch.
Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book represents the first of the ALZA CONFERENCE SERIES which will deal with a wide variety of topics of biomedical interest. These Conferences are planned to cover a range of subjects from the molecular level, such as drug receptor and drug membrane interactions, to the organ and organismal levels and the dynamics of drug therapy. This year's topic is 'PROSTAGLANDINS.' It is rapidly becoming clear that prosta glandins are of great interest and potential utility in therapeutics. An understanding of the role of prostaglandins in the regulation of cell processes should provide insight into the understanding of a variety of difficult and intransigent fields such as cancer, allergy, and transplant rejection. We hope that this Conference may focus attention on novel approaches to these areas. We wish to thank our distinguished Chairmen and guests for their attendance. The papers and dis cussions were prepared by Yvonne Hendrickson, using an ATS/360 Text-Editing System; we acknowledge with gratitude her skill, patience, and hard work. P.W.R. B.B.P.
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Taschenbuch. Zustand: Neu. Recent Advances in Prostaglandin, Thromboxane, and Leukotriene Research | Helmut Sinzinger (u. a.) | Taschenbuch | Einband - flex.(Paperback) | Englisch | 2013 | Springer Us | EAN 9781489918123 | Verantwortliche Person für die EU: Springer Nature Customer Service Center GmbH, Europaplatz 3, 69115 Heidelberg, productsafety[at]springernature[dot]com | Anbieter: preigu.