Poupon raoul e (12 Ergebnisse)
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Hardcover. Zustand: Good. No Jacket. Pages can have notes/highlighting. Spine may show signs of wear. ~ ThriftBooks: Read More, Spend Less.
- Hardcover
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hardcover. Zustand: Very Good. No Dust Jacket. Excellent, clean, unmarked condition. Stamp on back inside cover. Tiny dent on back cover.
- Hardcover
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Cloth/Laminated Boards. Zustand: Very Good. Zustand des Schutzumschlags: No d/j as Published. Type: Book The proceedings of a one-day symposium held in Chicago, USA, on November 6, 1997, provide an update for hepatologists, gastroenterologists, and basic scientists with an interest in primary biliary cirrhosis. New insights into… the pathogenesis and the natural history of the disease are discussed, and approaches to management of the complications as well as newer therapeutic options are presented.192pp.Slight marking at the base of the spine.
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Cloth. Zustand: Like New. Zustand des Schutzumschlags: Very Good. Type: Book The 1990s have seen an increasing number of supposedly active drugs for the treatment of chronic liver diseases, e.g. ursodeoxycholate for treatment of cholestatic conditions and alpha-interferon for the treatment of chronic viral hepatitis. However, in… all controlled studies, hard end-points such as survival or need for transplantation often cannot be obtained, owing to the prolonged course of chronic liver diseases up to the time of hepatic decompensation and death. Therefore, surrogate markers for the different conditions are sorely needed in order to assess the value of these novel treatment modalities. This collection of symposium papers defines surrogate markers and evaluates those frequently used in randomized clinical trials. Surrogate markers considered include different old and new serum markers of chronic liver disease, scores, liver biopsy and quantitative liver function tests. This volume should be of interest to clinicians concerned with prognostication and/or involved in clinical trials, clinical epidemiologists, members of governmental drug licensing agencies, and clinical research directors and their collaborators in the pharmaceutical industry. N.B.D/J spine slightly faded with slight mark to base of d/j spine.213pp.
- Hardcover
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Zustand: New. In.
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Zustand: New. In.
Weitere Bilder- Softcover
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EUR 140,10
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Taschenbuch. Zustand: Neu. Primary Biliary Cirrhosis | From Pathogenesis to Clinical Treatment | Keith D. Lindor (u. a.) | Taschenbuch | Einband - flex.(Paperback) | Englisch | 2012 | Springer Netherland | EAN 9789401060479 | Verantwortliche Person für die EU: Springer Nature Customer Service Center GmbH, Haberstr. 7, 69126 Heid…elberg, productsafety[at]springernature[dot]com | Anbieter: preigu.
- Hardcover
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EUR 178,14
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Gebunden. Zustand: New. The condition of prolonged obstructive jaundice with patent bile ducts was first described in 1851 by Addison and Gull of Guy s Hospital, London. The term primary biliary cirrhosis (PBC) was defined in 1950 by Ahrens and colleagues of the Rockefeller Instit.
- Softcover
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The condition of prolonged obstructive jaundice with patent bile ducts was first described in 1851 by Addison and Gull of Guy's Hospital, London. The term primary biliary cirrhosis (PBC) was defined in 1950 by Ahrens and colleagues of the Rockefeller… Institute, New York. The condition was considered rare but this changed in 1965 with the discovery of a definitive diagnostic serum mitochondrial antibody test and the recognition that a raised serum alkaline phosphatase value, often discovered incidentally, could be a diagnostic pointer. If the diagnosis is made earlier, the end stages are rarely reached as death is replaced by liver transplantation. On November 6th 1997, in Chicago, an International Faculty discussed in depth the clinical features, pathogenesis and treatment of PBC, no longer considered a rare disease. The course of PBC is long, but some 18 years after the discovery of a positive mitochondrial antibody test in a symptom free patient with normal serum biochemistry, 83% will have developed abnormal tests and 76% will be symptomatic. Identification of those who will progress rapidly is difficult. The serum antimitochondrial profile may be useful but this is a very specialist technique. Mathematical prognostic models are useful in therapeutic trials and in the selection and timing of patients for liver transplantation but have limited value in individual patients. An increasing serum bilirubin level remains the most important indicator of rapid progression. Its value however can be negated by the use of ursodeoxycholic acid which has a bilirubin-lowering effect.
- Softcover
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Zustand: New. The condition of prolonged obstructive jaundice with patent bile ducts was first described in 1851 by Addison and Gull of Guy s Hospital, London. The term primary biliary cirrhosis (PBC) was defined in 1950 by Ahrens and colleagues of the Rockefeller Instit.
- Hardcover
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EUR 249,15
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Zustand: New. Containing the proceedings of a one-day symposium held in Chicago, USA, on November 6, 1997, this work provides an update for hepatologists, gastroenterologists, and basic scientists with an interest in primary biliary cirrhosis. It can help foster new and better approaches for the management of patients with prima…ry biliary cirrhosis. Editor(s): Lindor, Keith D.; Heathcote, Jenny E.; Poupon, Raoul E. Num Pages: 176 pages, biography. BIC Classification: MJJ. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 234 x 156 x 12. Weight in Grams: 980. . 1998. 1998th Edition. hardcover. . . . . Books ship from the US and Ireland.
- Hardcover
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EUR 245,00
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Buch. Zustand: Neu. Neuware - The condition of prolonged obstructive jaundice with patent bile ducts was first described in 1851 by Addison and Gull of Guy's Hospital, London. The term primary biliary cirrhosis (PBC) was defined in 1950 by Ahrens and colleagues of the Rockefeller Institute, New York. The condition was considered… rare but this changed in 1965 with the discovery of a definitive diagnostic serum mitochondrial antibody test and the recognition that a raised serum alkaline phosphatase value, often discovered incidentally, could be a diagnostic pointer. If the diagnosis is made earlier, the end stages are rarely reached as death is replaced by liver transplantation. On November 6th 1997, in Chicago, an International Faculty discussed in depth the clinical features, pathogenesis and treatment of PBC, no longer considered a rare disease. The course of PBC is long, but some 18 years after the discovery of a positive mitochondrial antibody test in a symptom free patient with normal serum biochemistry, 83% will have developed abnormal tests and 76% will be symptomatic. Identification of those who will progress rapidly is difficult. The serum antimitochondrial profile may be useful but this is a very specialist technique. Mathematical prognostic models are useful in therapeutic trials and in the selection and timing of patients for liver transplantation but have limited value in individual patients. An increasing serum bilirubin level remains the most important indicator of rapid progression. Its value however can be negated by the use of ursodeoxycholic acid which has a bilirubin-lowering effect.
