Sprache: Englisch
Verlag: Royal Society of Chemistry, 2011
ISBN 10: 1849730504 ISBN 13: 9781849730501
Anbieter: Romtrade Corp., STERLING HEIGHTS, MI, USA
Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.
Sprache: Englisch
Verlag: Royal Society of Chemistry, 2011
ISBN 10: 1849730504 ISBN 13: 9781849730501
Anbieter: Romtrade Corp., STERLING HEIGHTS, MI, USA
Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.
Sprache: Englisch
Verlag: Royal Society of Chemistry, 2011
ISBN 10: 1849730504 ISBN 13: 9781849730501
Anbieter: Majestic Books, Hounslow, Vereinigtes Königreich
EUR 65,44
Anzahl: 4 verfügbar
In den WarenkorbZustand: New. pp. 286 52:B&W 6.14 x 9.21in or 234 x 156mm (Royal 8vo) Case Laminate on White w/Gloss Lam.
Sprache: Englisch
Verlag: Royal Society of Chemistry, 2011
ISBN 10: 1849730504 ISBN 13: 9781849730501
Anbieter: Romtrade Corp., STERLING HEIGHTS, MI, USA
Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.
Sprache: Englisch
Verlag: Royal Society of Chemistry, 2011
ISBN 10: 1849730504 ISBN 13: 9781849730501
Anbieter: Romtrade Corp., STERLING HEIGHTS, MI, USA
Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.
Sprache: Englisch
Verlag: Royal Society of Chemistry, 2011
ISBN 10: 1849730504 ISBN 13: 9781849730501
Anbieter: Romtrade Corp., STERLING HEIGHTS, MI, USA
Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.
Sprache: Englisch
Verlag: ROYAL SOCIETY OF CHEMISTRY, 2011
ISBN 10: 1849730504 ISBN 13: 9781849730501
Anbieter: Buchpark, Trebbin, Deutschland
Zustand: Sehr gut. Zustand: Sehr gut | Seiten: 270 | Sprache: Englisch | Produktart: Bücher | Keine Beschreibung verfügbar.
EUR 156,27
Anzahl: 15 verfügbar
In den WarenkorbHRD. Zustand: New. New Book. Shipped from UK. Established seller since 2000.
HRD. Zustand: New. New Book. Shipped from UK. Established seller since 2000.
Sprache: Englisch
Verlag: Royal Society of Chemistry, 2011
ISBN 10: 1849730504 ISBN 13: 9781849730501
Anbieter: Ria Christie Collections, Uxbridge, Vereinigtes Königreich
EUR 171,52
Anzahl: Mehr als 20 verfügbar
In den WarenkorbZustand: New. In.
Sprache: Englisch
Verlag: ROYAL SOCIETY OF CHEMISTRY, 2011
ISBN 10: 1849730504 ISBN 13: 9781849730501
Anbieter: moluna, Greven, Deutschland
EUR 163,54
Anzahl: Mehr als 20 verfügbar
In den WarenkorbZustand: New. This exemplary book gives an up-to-date perspective on the role of metal ions in neurodegeneration.Über den AutorrnrnDanilo Milardi obtained a degree in Industrial Chemistry from the University of Catania before going on to obtain a PhD.
Sprache: Englisch
Verlag: Royal Society of Chemistry, 2011
ISBN 10: 1849730504 ISBN 13: 9781849730501
Anbieter: Revaluation Books, Exeter, Vereinigtes Königreich
EUR 219,76
Anzahl: 2 verfügbar
In den WarenkorbHardcover. Zustand: Brand New. 1st edition. 270 pages. 9.75x6.50x0.75 inches. In Stock.
Buch. Zustand: Neu. Neuware - Since Alois Alzheimer described the results of his postmortem studies in 1906, significant strides have been made in understanding the pathogenesis of neurodegenerative diseases. Substantial evidence has accumulated indicating that diverse neurodegenerative disorders might share a common pathological mechanism: the misfolding, aggregation and accumulation of proteins (termed 'amyloid') in the brain. Metal ions have long been thought to catalyze protein misfolding initiating a cascade of events resulting in oxidative damage and neurodegeneration. They have, consequently, been seen as a suitable pharmacological target. However, drugs aimed at simply removing excess metals or interfering in amyloid deposition were unsuccessful and scientists have been forced to review the classical hypothesis. The latest advances suggest that deficiencies in protein homeostasis may lead to cell dysfunction and disease. Furthermore, small molecules with the potential to control metal homeostasis, or metallostasis, are expected to provide the framework for the design of novel proteostasis regulators. This book provides an up-date on the latest developments in this fast moving field. Traditional views concerning the relationship between the physio-pathological cycles of copper, zinc, iron, aluminium and the evolution of life, are compared with emerging ideas in the neuroscience of metal ions. Topics covered emphasize the importance of metals and oxidation chemistry to neuroscientists as well as providing a wider, multidisciplinary background to chemists who are attracted by these fascinating subjects. The text starts with a chapter on chemical evolution, the brain and metallomics which describes the brain's natural defences to adverse conditions. It then goes on to cover the chemistry and biology of proteostasis, environmental factors, and the role played by membranes in protein misfolding. The remaining chapters cover the role of metals and oxidative stress in Alzheimer's Disease, Parkinsonism, ALS and other neurodegenerative diseases. The book is suitable for academics, those working in industry, and postgraduate students.