Matilda bingham (19 Ergebnisse)

Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Zustand: New. pp. 614.

Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Zustand: New. pp. 268.

Zustand: Sehr gut. Zustand: Sehr gut | Seiten: 268 | Sprache: Englisch | Produktart: Bücher | Transporters are proteins that span the plasma membrane and regulate the traf?c of small molecules in and out of the cell. They play a particularly important role in chemical signalling between neurons in the CNS, where they act to control the concentration of neurotransmitters in the synapse. In most systems the termination of chemical transmission is achieved by rapid uptake of the transmitter molecule from the synapse by transporters located on the synaptic terminal or surrounding glial cells. Another key role for transporters is in excluding undesirable xenobiotics from the cell, whilst allowing key molecules required for the cell life cycle to enter. It is incre- ingly recognised that these ef?ux or uptake transporters respectively, play an important role in the disposition of many marketed drugs, and whilst the ?eld of drug transport is yet to attain the level of maturity of drug metabolism,itiscertaintobeofincreasingimportance infuturedrugdisc- ery programmes. 2 Transporter Classification Transporters can be classed into two main families; the ATP binding c- sette (ABC) family, and the solute carrier (SLC) family. The SLC family is a very broad categorisation which encompasses, amongst others, three - portant families of transporters for organic molecules; the major facilitator superfamily (MFS) and two neurotransmitter transporter families, the neu- transmitter; sodium symporter (NSS, or SLC6) and the dicarboxylate/amino + + acid:cation (Na or H ) symporter (DAACS, or SLC1) family.…

Hardcover. Zustand: Brand New. 432 pages. 9.29x1.57x6.14 inches. In Stock.

Taschenbuch. Zustand: Neu. Transporters as Targets for Drugs | Susan Napier (u. a.) | Taschenbuch | xiv | Englisch | 2010 | Springer | EAN 9783642099694 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.…

Zustand: New. In English.

Zustand: New. In English.

Gebunden. Zustand: New. This is a wide scope and in-depth coverage of the state of the art and future directions in drug discovery for major psychiatric disorders.&Uumlber den AutorrnrnZoran Rankovic is a Senior Research Fellow and a Head of Medicinal Chemistry se.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - M. Bingham - S. Napier: Overview: Transporters as Targets for Drug DiscoveryI. Sylte - A.W. Ravna - G. Sager - S.G. Dahl: Membrane Transporters: Structure, Function and Targets for Drug DesignG.A. Whitlock - M.D. Andrews - A.D. Brown - P.V Fish - A. Stobie - F. Wakehut: Design of Monoamine Reuptake Inhibitors - SSRIs, SNRIs and NRIsA. Hauck Newman - J.L. Katz: Atypical Dopamine Uptake Inhibitors that Provide Clues About Cocaine's Mechanism at the Dopamine Transporter Z. Chen - J. Yang - P. Skolnick: The Design, Synthesis and Structure-Activity Relationship of Mixed Serotonin, Norepinephrine and Dopamine Uptake InhibitorsG. Antoni - J. Sörensen - H. Hall: Molecular Imaging of Transporters with Positron Emission TomographyR. Bridges - S.A. Patel: Pharmacology of Glutamate Transport in the CNS: Substrates and Inhibitors of Excitatory Amino Acid Transporters (EAATs) and the Glutamate/Cystine Exchanger System xcR. Gilfillan - J. Kerr G. - Walker - G. Wishart: Glycine Transporters and Their Inhibitors.…

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - M. Bingham - S. Napier: Overview: Transporters as Targets for Drug DiscoveryI. Sylte - A.W. Ravna - G. Sager - S.G. Dahl: Membrane Transporters: Structure, Function and Targets for Drug DesignG.A. Whitlock - M.D. Andrews - A.D. Brown - P.V Fish - A. Stobie - F. Wakehut: Design of Monoamine Reuptake Inhibitors - SSRIs, SNRIs and NRIsA. Hauck Newman - J.L. Katz: Atypical Dopamine Uptake Inhibitors that Provide Clues About Cocaine's Mechanism at the Dopamine Transporter Z. Chen - J. Yang - P. Skolnick: The Design, Synthesis and Structure-Activity Relationship of Mixed Serotonin, Norepinephrine and Dopamine Uptake InhibitorsG. Antoni - J. Sörensen - H. Hall: Molecular Imaging of Transporters with Positron Emission TomographyR. Bridges - S.A. Patel: Pharmacology of Glutamate Transport in the CNS: Substrates and Inhibitors of Excitatory Amino Acid Transporters (EAATs) and the Glutamate/Cystine Exchanger System xcR. Gilfillan - J. Kerr G. - Walker - G. Wishart: Glycine Transporters and Their Inhibitors. …

Zustand: New. In English.

Paperback. Zustand: Brand New. reprint edition. 267 pages. 9.29x6.22x0.71 inches. In Stock.

Hardcover. Zustand: Brand New. 432 pages. 9.29x1.57x6.14 inches. In Stock.

Hardcover. Zustand: Brand New. 1st edition. 253 pages. 9.45x6.38x0.87 inches. In Stock.

Buch. Zustand: Neu. Neuware - 1.An authorative reference on the background and advances in psychiatric drug discovery2.Current treatments often have unpleasant side effects, there is a need to develop more effective treatments3.Medicinal chemists, pharmacologists, biochemists, those working in psychiatric drug development4.MedChemComm, Issues in Toxicology Series5.Covers the evolution, major advances, challenges and future directions in drug discovery and medicinal chemistry for major psychiatric disorders.…