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Zustand: Good. 1986th Edition. Former library copy. Pages intact with minimal writing/highlighting. The binding may be loose and creased. Dust jackets/supplements are not included. Includes library markings. Stock photo provided. Product includes identifying sticker. Better World Books: Buy Books. Do Good.

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Paperback. Zustand: Brand New. reprint edition. 384 pages. 10.00x7.01x0.88 inches. In Stock.

Paperback. Zustand: Brand New. 548 pages. 9.25x6.10x1.24 inches. In Stock.

Taschenbuch. Zustand: Neu. Boundaries between Promotion and Progression during Carcinogenesis | Oscar Sudilovsky (u. a.) | Taschenbuch | 384 S. | Englisch | 2012 | Springer | EAN 9781468459968 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.

Taschenbuch. Zustand: Neu. Tumor Invasion and Metastasis | L. A. Liotta (u. a.) | Taschenbuch | 544 S. | Englisch | 2012 | Springer | EAN 9789400975132 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The pUrpOSE! of this conference was not to define the two areas that are being bound, which might be a well nigh impossible proposition. Rather, its focus was to concentrate on the mechanistic similarities between promotion and progression. Are the areas involved within the boundaries a continuum Are these two simultaneous processes Or are some of the affected cells in the stage of promotion when at the same time others have undergone irreversi ble changes tha. t position them in the stage of progression Or are these two stages the same thing, but called by different names To explore such concepts we assembled investigators with various back grounds and asked them to specifically address these and other questions about 'The Boundaries', within the context of the session to which they con tributed. The conference lasted two and a half days, from Wednesday to Friday. There were at least four speakers per session with morning and after noon sessions each day, except on Friday when the meeting ended at noon. The first day, each speaker had 25 minutes to present a position, followed by five minutes of discussion. At the end of the session there were 40 or 50 minutes of exchange on all the issues examined. For the remaining days, there were 25 minutes of presentation and 15 minutes of discussion.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The clinical significance of tumor spread has always been appreciated. Yet, in spite of the pioneering work and outstanding contributions of investigators such as D. Coman, H. Green, B. Fisher, S. Wood and I. Zeidman, studies on metastasis rarely achieved the popularity afforded to more esoteric areas of tumor biology. Tumor dissemination, occurring as it does in a responding host and being composed of a series of dynamic int~ractions, is a highly complex phenomenon. Few investigators were brave enough to attempt to unravel the mechanisms involved. Paradoxically, this very complexity may have contributed, in part, to the recent upsurge of interest in metastasis research. More and more researchers are becoming fascinated by the complexities of the cellular interactions involved in tumor spread. Accompanying this intellectual stimulation have been technological advances in related fields which allow the derivation of new model systems. The mechanisms of metastatic spread are increasingly amenable to both the reductionist and holistic approaches and it is the purpose of this volume to present many of these model systems while emphasizing the intricacy and complexity of the processes they mimic. We have attempted to emphasize two topics not previously covered in depth in previous books on metastases. These are in vitro models of invasion and in teractions of tumor cells with connective tissue.

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Hardcover. Zustand: Very Good with no dust jacket. First Edition (?). Unmarked, except for intitials on insidee cover page. ; Book Description; Spine has no signs of creasing. Pages are clean and not marred by notes or folds. Covers are square with minor wear. Ships Safe and Fast. Published without Dust Jacket. In this volume security specialists, peace researchers, environmental scholars, demographers as well as climate, desertification, water, food and urbanisation specialists from the Middle East and North Africa, Europe and North America review security and conflict prevention in the Mediterranean. They also analyse NATO s Mediterranean security dialogue and offer conceptualisations on security and perceptions of security challenges as seen in North and South. The latter half of the book analyses environmental security and conflicts in the Mediterranean and environmental consequences of World War II, the Gulf War, the Balkan wars and the Middle East conflict. It also examines factors of global environmental change: population growth, climate change, desertification, water scarcity, food and urbanisation issues as well as natural disasters. Furthermore, it draws conceptual conclusions for a fourth phase of research on human and environmental security and peace as well as policy conclusions for cooperation and partnership in the Mediterranean in the 21st century.; Hexagon Series on Human and Environmental Security and Peace; 10.94 X 8.19 X 1.97 inches; 1137 pages DG4.

Taschenbuch. Zustand: Neu. Biochemistry and Molecular Genetics of Cancer Metastasis | Proceedings of the Symposium on Biochemistry and Molecular Genetics of Cancer Metastasis Bethesda, Maryland - March 18-20, 1985 | Karoly Lapis (u. a.) | Taschenbuch | xviii | Englisch | 2011 | Springer | EAN 9781461294160 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.

Zustand: Good. Your purchase helps support Sri Lankan Children's Charity 'The Rainbow Centre'. Ex-library, so some stamps and wear, and may have sticker on cover, but in good overall condition. Our donations to The Rainbow Centre have helped provide an education and a safe haven to hundreds of children who live in appalling conditions.

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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The success rate for treatment of primary neoplasms has improved sig nificantly due to improved surgical, radiotherapy, and chemotherapy methods, and by supportive patient care. In contrast, the treatment of cancer metastases, the cause of most cancer deaths, has not been very successful. Approximately 50% or more of patients with primary malignant neoplasms already have established metastases. Consequently, the most important problem in cancer treatment is the destruction or prevention of metastases. Metastases research has obvious clinical importance. Yet it has only been recently that investigators have attempted to study the mechanisms in volved in this process. This is in part due to the complexity of metastases formation. A metastatic colony is the result of a complicated series of steps involving mUltiple tumor host interactions. It is expected that multiple biochemical factors and gene products derived both from the host and the tumor cell may be required for the metastasizing tumor cell to invade, survive host defenses, travel in the circulation, arrest and adhere in the target organ, invade out, and grow as a metastatic colony. Some of these factors have recently been identified by investigators who have focused on individual steps in the metastatic process and have employed new technologies in immunology, biochemistry and molecular biology. The purpose of this volume is to capture some of the excitement in the field of metastases based on such new discoveries.

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The success rate for treatment of primary neoplasms has improved sig nificantly due to improved surgical, radiotherapy, and chemotherapy methods, and by supportive patient care. In contrast, the treatment of cancer metastases, the cause of most cancer deaths, has not been very successful. Approximately 50% or more of patients with primary malignant neoplasms already have established metastases. Consequently, the most important problem in cancer treatment is the destruction or prevention of metastases. Metastases research has obvious clinical importance. Yet it has only been recently that investigators have attempted to study the mechanisms in volved in this process. This is in part due to the complexity of metastases formation. A metastatic colony is the result of a complicated series of steps involving mUltiple tumor host interactions. It is expected that multiple biochemical factors and gene products derived both from the host and the tumor cell may be required for the metastasizing tumor cell to invade, survive host defenses, travel in the circulation, arrest and adhere in the target organ, invade out, and grow as a metastatic colony. Some of these factors have recently been identified by investigators who have focused on individual steps in the metastatic process and have employed new technologies in immunology, biochemistry and molecular biology. The purpose of this volume is to capture some of the excitement in the field of metastases based on such new discoveries.

Zustand: New. Proceedings of the Symposium on Biochemistry and Molecular Genetics of Cancer Metastasis, Bethesda, Maryland, March 18-20, 1985 Editor(s): Lapis, K.; Liotta, L. A.; Rabson, A. S. Series: Developments in Oncology. Num Pages: 334 pages, 1, black & white illustrations. BIC Classification: MJCL. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly. Dimension: 234 x 156 x 20. Weight in Grams: 675. . 1986. Hardback. . . . . Books ship from the US and Ireland.

Zustand: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher | Recent experimental evidence has made it increasingly clear In particular, this volume reviews the discrete steps involved that the properties of invasive, malignant cells during tumor in metastatic invasion: the interaction of invasive tumor cells development substantially impact on the host. This is under­ with extracellular matrices, the basement membrane, attach­ scored by a variety of biochemical properties of tumor cells ment to extracellular matrices, local proteolytic degradation during their differentiation and metastatic dissemination. of matrices, and the locomotion of invasive tumor cells These properties can be analyzed at different stages of tumor through such areas of localized degradation. The critical growth and progression and this volume explores the role of the cell surface in secondary tumor formation is characteristics of primary tumors as well as the shared reviewed as are important advances in the molecular biology characteristics of both primary and secondary tumors. of metastasis initiation and maintenance. Recent advances The primary tumor comes into existence following in the role of DNA methylation in the generation of tumor preneoplastic biochemical and cellular events that ultimate­ cell heterogeneity and tumor progression are also critically ly result in malignant transformation. Various aspects of summarized. Chapters in this volume also review molecular metabolism, predetermined by nutritional status, often play aspects of metastatic progression, and the use of the tech­ a basic role. Obesity, for example, is cancer-promoting. Cell nologies of DNA transfection and somatic cell fusion in the surface carbohydrates, cytoskeletal proteins, glycoproteins, exploration of molecular aspects of metastatic progression.

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Recent experimental evidence has made it increasingly clear In particular, this volume reviews the discrete steps involved that the properties of invasive, malignant cells during tumor in metastatic invasion: the interaction of invasive tumor cells development substantially impact on the host. This is under with extracellular matrices, the basement membrane, attach scored by a variety of biochemical properties of tumor cells ment to extracellular matrices, local proteolytic degradation during their differentiation and metastatic dissemination. of matrices, and the locomotion of invasive tumor cells These properties can be analyzed at different stages of tumor through such areas of localized degradation. The critical growth and progression and this volume explores the role of the cell surface in secondary tumor formation is characteristics of primary tumors as well as the shared reviewed as are important advances in the molecular biology characteristics of both primary and secondary tumors. of metastasis initiation and maintenance. Recent advances The primary tumor comes into existence following in the role of DNA methylation in the generation of tumor preneoplastic biochemical and cellular events that ultimate cell heterogeneity and tumor progression are also critically ly result in malignant transformation. Various aspects of summarized. Chapters in this volume also review molecular metabolism, predetermined by nutritional status, often play aspects of metastatic progression, and the use of the tech a basic role. Obesity, for example, is cancer-promoting. Cell nologies of DNA transfection and somatic cell fusion in the surface carbohydrates, cytoskeletal proteins, glycoproteins, exploration of molecular aspects of metastatic progression.

Hardcover. Zustand: Brand New. 250 pages. 10.00x8.00x0.63 inches. In Stock.

Zustand: New. Editor(s): Liotta, L. A. Series: Cancer Growth and Progression. Num Pages: 250 pages, biography. BIC Classification: MJCL. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly. Dimension: 280 x 216 x 16. Weight in Grams: 945. . 1988. Hardback. . . . . Books ship from the US and Ireland.