Sprache: Englisch
Verlag: William Harvey Research Conferences, 2003
ISBN 10: 0953403912 ISBN 13: 9780953403912
Anbieter: Better World Books Ltd, Dunfermline, Vereinigtes Königreich
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In den WarenkorbZustand: Good. 1st Edition. Former library copy. Pages intact with minimal writing/highlighting. The binding may be loose and creased. Dust jackets/supplements are not included. Includes library markings. Stock photo provided. Product includes identifying sticker. Better World Books: Buy Books. Do Good.
Sprache: Englisch
Verlag: Kluwer Academic Publishers, Dordrecht, 1998
ISBN 10: 0792387295 ISBN 13: 9780792387299
Anbieter: PsychoBabel & Skoob Books, Didcot, Vereinigtes Königreich
EUR 6,83
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In den Warenkorbhardcover. Zustand: Very Good. VG+ hardcover. 150 pp.
Anbieter: Ammareal, Morangis, Frankreich
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In den WarenkorbHardcover. Zustand: Très bon. Ancien livre de bibliothèque avec équipements. Edition 1996. Ammareal reverse jusqu'à 15% du prix net de cet article à des organisations caritatives. ENGLISH DESCRIPTION Book Condition: Used, Very good. Former library book. Edition 1996. Ammareal gives back up to 15% of this item's net price to charity organizations.
Anbieter: Hay-on-Wye Booksellers, Hay-on-Wye, HEREF, Vereinigtes Königreich
EUR 4,10
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In den WarenkorbZustand: Fine.
Sprache: Englisch
Verlag: Kluwer Academic Publishers, 1998
ISBN 10: 0792387295 ISBN 13: 9780792387299
Anbieter: Fireside Bookshop, Stroud, GLOS, Vereinigtes Königreich
Verbandsmitglied: PBFA
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In den WarenkorbCloth/Laminated Boards. Zustand: Very Good. First Edition. Type: Book This volume is the proceedings of the William Harvey Research Conference held in Cannes, France, on the 20th and 21st March, 1997. It describes the present knowledge of the structures of the cyclooxygenase isoforms and the experimental and clinical effects of selective inhibitors of cyclooxygenase-2. The pathophysiological significance of the cyclooxygenase enzymes in tumorigenesis, programmed cell death, vascular disease and asthma is also covered.150pp.
Sprache: Englisch
Verlag: Kluwer Academic Publishers, 1999
ISBN 10: 0792387295 ISBN 13: 9780792387299
Anbieter: Fireside Bookshop, Stroud, GLOS, Vereinigtes Königreich
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In den WarenkorbCloth/Laminated Boards. Zustand: Very Good. Reprint. Type: Book This volume is the proceedings of the William Harvey Research Conference held in Cannes, France, on the 20th and 21st March, 1997. It describes the present knowledge of the structures of the cyclooxygenase isoforms and the experimental and clinical effects of selective inhibitors of cyclooxygenase-2. The pathophysiological significance of the cyclooxygenase enzymes in tumorigenesis, programmed cell death, vascular disease and asthma is also covered.150pp.
Sprache: Englisch
Verlag: Kluwer Academic Publishers, 1996
ISBN 10: 0792387147 ISBN 13: 9780792387145
Anbieter: Fireside Bookshop, Stroud, GLOS, Vereinigtes Königreich
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In den WarenkorbCloth/Laminated Boards. Zustand: Very Good. Type: Book This volume of conference proceedings reviews the general pathophysiological significance of the isoforms of cyclooxygenase, and the likely value of selective COX-2 inhibitors in the treatment of rheumatoid conditions. Also covered is the possible use of antibodies against cytokines and cell adhesion receptors in the treatment of inflammatory conditions. N.B.Top edge front board slightly bumped.147pp.
Sprache: Englisch
Verlag: Kluwer Academic Publishers, 1996
ISBN 10: 0792387147 ISBN 13: 9780792387145
Anbieter: Fireside Bookshop, Stroud, GLOS, Vereinigtes Königreich
Verbandsmitglied: PBFA
EUR 11,91
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In den WarenkorbCloth/Laminated Boards. Zustand: Very Good. Type: Book This volume of conference proceedings reviews the general pathophysiological significance of the isoforms of cyclooxygenase, and the likely value of selective COX-2 inhibitors in the treatment of rheumatoid conditions. Also covered is the possible use of antibodies against cytokines and cell adhesion receptors in the treatment of inflammatory conditions. N.B.Top edge front board slightly bumped.147pp.
Anbieter: Hay-on-Wye Booksellers, Hay-on-Wye, HEREF, Vereinigtes Königreich
EUR 11,88
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In den WarenkorbZustand: Fine.
Sprache: Englisch
Verlag: Kluwer Academic Publishers, 1996
ISBN 10: 0792388976 ISBN 13: 9780792388975
Anbieter: Fireside Bookshop, Stroud, GLOS, Vereinigtes Königreich
Verbandsmitglied: PBFA
EUR 35,73
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In den WarenkorbCloth. Zustand: Like New. Type: Book This volume contains the proceedings of the William Harvey Conference held in London, 10-11 October, 1995. It covers the molecular biology and physiological functions of the cyclo-oxygenase enzymes, as well as the experimental and clinical aspects of the recently discovered inhibitors of the inducible cyclooxygenase. Particular attention has been directed at the discussion of the selectivity of non-steroid anti-inflammatory drugs for cyclooxygenase-2 and their propensity to cause gastric and kidney damage. 248pp.
Anbieter: Ria Christie Collections, Uxbridge, Vereinigtes Königreich
EUR 54,01
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In den WarenkorbZustand: New. In.
Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.
Sprache: Englisch
Verlag: Kluwer Academic Publishers, 1996
ISBN 10: 0792388976 ISBN 13: 9780792388975
Anbieter: NEPO UG, Rüsselsheim am Main, Deutschland
Gebundene Ausgabe. Zustand: Sehr gut. 200 Seiten ex Library Book aus einer wissenschafltichen Bibliothek Sprache: Englisch Gewicht in Gramm: 550.
Sprache: Englisch
Verlag: Kluwer Academic Publishers, 1996
ISBN 10: 0792388976 ISBN 13: 9780792388975
Anbieter: NEPO UG, Rüsselsheim am Main, Deutschland
Gebundene Ausgabe. Zustand: Sehr gut. 200 Seiten ex Library Book aus einer wissenschafltichen Bibliothek Sprache: Englisch Gewicht in Gramm: 550.
Sprache: Englisch
Verlag: , Kluwer Academic Publishers, 1996
ISBN 10: 0792388976 ISBN 13: 9780792388975
Anbieter: Versandantiquariat Ingo Lutter, Buchholz, Deutschland
Buch hat leichte Gebrauchsspuren ( Lesespuren ) Englisch ; Gesamtzustand: Gut Hardcover Deutsch 570g.
Anbieter: Ria Christie Collections, Uxbridge, Vereinigtes Königreich
EUR 114,51
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In den WarenkorbZustand: New. In.
Anbieter: Ria Christie Collections, Uxbridge, Vereinigtes Königreich
EUR 114,51
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In den WarenkorbZustand: New. In.
Anbieter: Ria Christie Collections, Uxbridge, Vereinigtes Königreich
EUR 114,51
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In den WarenkorbZustand: New. In.
Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.
Anbieter: Ria Christie Collections, Uxbridge, Vereinigtes Königreich
EUR 126,62
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In den WarenkorbZustand: New. In.
Anbieter: Ria Christie Collections, Uxbridge, Vereinigtes Königreich
EUR 126,62
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In den WarenkorbZustand: New. In.
Anbieter: Herbst-Auktionen, Detmold, Deutschland
Manuskript / Papierantiquität Signiert
Autogrammkarte (16° mit aufgezogenem Illustriertenbild), mit Empfehlung eigenhändig signiert.
Anbieter: Revaluation Books, Exeter, Vereinigtes Königreich
EUR 148,10
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In den WarenkorbPaperback. Zustand: Brand New. 150 pages. 9.45x6.30x0.37 inches. In Stock.
Anbieter: Revaluation Books, Exeter, Vereinigtes Königreich
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In den WarenkorbPaperback. Zustand: Brand New. 1996 edition. 160 pages. 9.25x6.10x0.47 inches. In Stock.
Anbieter: Revaluation Books, Exeter, Vereinigtes Königreich
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In den WarenkorbPaperback. Zustand: Brand New. reprint edition. 248 pages. 8.75x6.00x0.75 inches. In Stock.
Anbieter: preigu, Osnabrück, Deutschland
Taschenbuch. Zustand: Neu. Selective COX-2 Inhibitors | Pharmacology, Clinical Effects and Therapeutic Potential | John R. Vane (u. a.) | Taschenbuch | ix | Englisch | 2012 | Springer | EAN 9789401060417 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
Taschenbuch. Zustand: Neu. New Targets in Inflammation | Inhibitors of COX-2 or Adhesion Molecules Proceedings of a conference held on April 15-16, 1996, in New Orleans, USA, supported by an educational grant from Boehringer Ingelheim | N. Bazan (u. a.) | Taschenbuch | ix | Englisch | 2012 | Springer Netherland | EAN 9789401062657 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
Anbieter: moluna, Greven, Deutschland
EUR 124,63
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In den WarenkorbZustand: New.
Anbieter: AHA-BUCH GmbH, Einbeck, Deutschland
Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The mainstay of therapy for rheumatoid disease is the non-steroid antiinflammatory drugs (NSAIDs), despite their inherent gastrointestinal toxicity and ability to cause renal damage in susceptible patients. The theory that the beneficial and toxic effects of NSAIDs stem from a reduction in prostanoid production through inhibition of cyclooxygenase implied that particular toxicities were inevitable with NSAIDs and would always be correlated with efficacy. However, over the years, it became apparent that at therapeutic doses, some NSAIDs had greater toxic side-effects than others, a fact not explained by the general theory. A significant clarification arose from the discovery that there are two distinct isoforms of COX, a constitutive enzyme (COX-I) responsible for the production of prostanoids necessary for platelet aggregation and protection of the gastric mucosa and kidney; and an inducible enzyme (COX-2) that is newly synthesized at sites of tissue damage and produces prostaglandins that manifest pathological effects. It became clear that different NSAIDs had greater or lesser effects on COX-I when used in therapeutic doses, explaining the variation in side-effects. ' The elucidation of the crystal structure of these different enzymes and the skills of medicinal chemists have led to the synthesis of new chemicals with a selectivity for the inducible enzyme, and thus with therapeutic efficacy without those toxic effects result ing from inhibition of the constitutive enzyme.
Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - For the past 100 years the mainstay of therapy for rheumatoid arthritis (RA) has been aspirin or other drugs of the non-steroid anti-inflammatory group. In 1971 Vane pro posed that both the beneficial and toxic actions of these drugs was through inhibition of prostaglandin synthesis. The recent discovery that prostaglandins responsible for pain and other symptoms at inflammatory foci are synthesized by an inducible cyclooxygenase (COX-2) that is encoded by a gene distinct from that of the consti tutive enzyme (COX-I) provided a new target for therapy of RA. A drug that would selectively inhibit COX-2 would hopefully produce the symptomatic benefit provided by existing NSAIDs without the gastrointestinal and renal toxicity due to the inhibition of COX-I. Drugs selective for COX-2 are now available. Experimental studies have shown them to be effective with minimal toxicity, and in clinical trials gastric and renal toxicities are less. Highly selective COX-2 inhibitors, perhaps designed with knowledge of the crystal structures of COX-I and COX-2, are also available. Other experimental studies, including those in animals lacking effective genes for COX-lor COX-2 and in experimental carcinomas, suggest there is still much to be learned of the pathophysiological functions of these enzymes. The inflammatory response is a complex reaction involving many mediators that derive from white blood cells, endothelial cells and other tissues. Preliminary data have revealed that inhibitors of the cytokines and adhesion molecules that play a crucial role in the migration of white cells to inflammatory sites may be useful in RA.