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Zustand: New. 2024. 1st Edition. hardcover. . . . . . Books ship from the US and Ireland.
Anbieter: preigu, Osnabrück, Deutschland
Buch. Zustand: Neu. RNA as a Drug Target | The Next Frontier for Medicinal Chemistry | John Schneekloth (u. a.) | Buch | Methods and Principles in Medicinal Chemistry | 416 S. | Englisch | 2024 | Wiley-VCH GmbH | EAN 9783527351008 | Verantwortliche Person für die EU: Wiley-VCH GmbH, Boschstr. 12, 69469 Weinheim, product-safety[at]wiley[dot]com | Anbieter: preigu.
Buch. Zustand: Neu. Neuware -Discover a new paradigm in drug discovery that greatly expands the space of addressable drug targets and potential novel drugsWiley-VCH GmbH, Boschstraße 12, 69469 Weinheim 392 pp. Englisch.
Anbieter: AHA-BUCH GmbH, Einbeck, Deutschland
Buch. Zustand: Neu. Neuware - Provides the concepts and tools for developing drug-like small molecules that selectively target RNA rather than proteins, including the first successful examples from the development pipeline of big pharma.
Buch. Zustand: Neu. Neuware -Discover a new paradigm in drug discovery that greatly expands the space of addressable drug targets and potential novel drugs Existing paradigms for drug discovery have focused largely on enzymes and other proteins as drug targets. In recent years, however, different varieties of ribonucleic acids have emerged as a viable focus for target-based drug discovery, with the potential to revolutionize the strategy and approach for this essential step in the drug development process. RNA as a Drug Target: The Next Frontier for Medicinal Chemistry offers a practice-oriented introduction to developing drug-like small molecules that selectively modulate both coding and non-coding RNAs. Beginning with a description and characterization of existing druggable RNAs, the book discusses how to approach different RNA targets for drug discovery. The result is a crucial resource for targeting RNAs and creating the next generation of life-saving pharmaceuticals. RNA as a Drug Target readers will also find: - A complete 'toolbox' for working with RNA, from structure determination to screening and lead generation techniques - A wide range of addressable targets and mechanisms, including splicing modulation, riboswitches, targeted degradation, and more - Authoritative discussion of the potential of RNA-targeted small molecule therapeutics for drugging the epitranscriptome RNA as a Drug Target provides an expert introduction to a new frontier in pharmaceutical research for medicinal chemists, biochemists, molecular biologists, and members of the pharmaceutical industry. Englisch.