john d haley (12 Ergebnisse)

Paperback. Zustand: Brand New. 94 pages. 11.00x8.50x0.22 inches. In Stock.

Soft cover. Zustand: Very Good. ORIGINAL 1977 PUBLICATION; Softcover, ex-library; in very good condition. Book.

Zustand: Fair. Spuren von Feuchtigkeit / Nässe; Leichte Rillen / Abschürfungen / Risse / Knicke. The epidermal growth factor (EGF) receptor and its downstream signaling networks are crucial in tumor development and maintenance, driving the search for targeted anti-EGF receptor therapies. Extensive research has detailed the EGF receptor's structure, ligand binding domains, intrinsic tyrosine kinase function, and interactions with signaling adaptor proteins like SH2, PTB, and SH3, which are essential for signal transduction. The EGF receptor serves as a central hub for various signaling pathways and interacts with three other family receptors, forming dimers and oligomers in response to at least eleven ligands, some of which have overlapping or distinct functions. This interaction activates multiple second messenger proteins and facilitates cross-talk between systems, adding complexity to the signaling landscape. However, the cross-regulation of the EGF receptor with other anti-apoptotic, mitogenic, and metabolic signaling systems remains less understood. New findings continue to emerge from studying these interactions, although a significant challenge has been the tendency to define signaling pathways without considering their tissue-specific or cell-interaction contexts.

Soft cover. Zustand: Very Good. ORIGINAL 1977 PUBLICATION; Softcover, comb-bound; ex-library; in very good condition. Book.

Soft cover. Zustand: Very Good. Softcovers; comb-bound; owner's stamps; minor edgewear; small tear at top of rear wrap; o/w in very good condition. Book.

Zustand: very good. from the preface, "This guidebook has been prepared to provide geologic information on the Ozark Mountains, Arkansas Valley, and the Ouachita Mountains." DQ4. softcover, library markings, 79 pages, 2 foldouts back of book, illustrated.

Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Zustand: New. pp. xi + 393 Illus.

Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Taschenbuch. Zustand: Neu. EGFR Signaling Networks in Cancer Therapy | William John Gullick (u. a.) | Taschenbuch | xi | Englisch | 2011 | Humana Press | EAN 9781617378539 | Verantwortliche Person für die EU: Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.

Paperback. Zustand: Brand New. 404 pages. 10.24x7.60x0.96 inches. In Stock.

Softcover. Zustand: Very Good. Magazine proof. Small octavo. Perfect bound. Illustrated paper wrappers. Rubbed with vertical fold extending through all the wraps, very good or better. The editor's corrected copy for the printer of this literary magazine from Edinburgh Scotland with printed versos and rectos followed by alternating blank sheets, various editorial marks throughout, and taped in poem now loose. Contributors to this issue include Hird, Gael Turnbull, Phyllis Lyth, Edward Mackin, J. Phoenice, Celia Randall, D.W. Broadbridge, Phillippa Berlyn, Frances Harland, Moria O'Donaghoe, Geoff Richman, Martin Haley, Roy MacGregor-Hastie, Paul Callan, Richard Milner, Eric Nixon, W. Sanderson, John Hales-Tooke, Gloria Evans Davies, Carla Lanyon Lanyon, Kenneth S. Kitchin, Paul Greene, Gordon Harris, W.H. Boore, Dorothy Stringer, Maurice Tasnier, R.L. Cook, John Lucas, and Andrew Molloy Carson.