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Zustand: New. In.

Gebunden. Zustand: New. The aetiology of the chronic inflammatory bowel diseases - Crohn s disease and ulcerative colitis - is still enigmatic. The therapeutic approach has therefore traditionally focused on anti-inflammatory principles, including corticosteroids and aminosali.

Buch. Zustand: Neu. Neuware - The aetiology of the chronic inflammatory bowel diseases - Crohn's disease and ulcerative colitis - is still enigmatic. The therapeutic approach has therefore traditionally focused on anti-inflammatory principles, including corticosteroids and aminosalicylates. Since a significant proportion of patients is steroid-dependent or refractory and because of the problematic side-effects of long-term systemic steroids, active immunosuppression has gained acceptance in the field. The classical immunosuppressants azathioprine and 6-mercaptopurine have long been evidence-based in IBD, but underused. Recently, methotrexate and cyclosporine have also been proven to be effective in certain situations. Newer drugs like tacrolimus, mycophenolate and others may be similarly useful but their potential is still unclear. Finally, the immune modifiers including IL-10 and TNF-antibodies have been successfully subjected to controlled trials. Other experimental drugs discussed in this book are on the horizon. This volume is the Proceedings of Falk Symposium 119 held in Freiburg-im-Breisgau, Germany, October 3-4, 2000, and covers systematically the field of immunosuppression in inflammatory bowel diseases. It is hoped that it will further the prudent use of these drugs in the proper clinical situations by increasing our understanding of both the mechanisms of action and the clinical benefit to the patient.…

Paperback. Zustand: Fair. First Edition. Pages 36-68. Features: Anson Southard Marshall - article with nice one-page illustration; "Golden Days"; A Journey from New Hampshire to Philadelphia Half a Century Ago; My Wife's Aesthetic Soul; The Assassination of President Garfield; Massachusetts Coinage and Coins; Beaver Brook; New Hampshire State Normal School; Letter From John Farmer to Gov. William Plumer; William H.Y. Hackett; Letter from John Adams to Gov. William Plumer; Laudate Dominum; A Curious Relic. Ads and editorial comment on last six pages stroked out. Above-average external wear and soiling. Faint prior owner's name atop front cover. A worthy reference copy. Stuart, F.T (illustrator).…