Jacques ghysdael (21 Ergebnisse)

Zustand: New. In English.

Zustand: New. In English.

Paperback. Zustand: Brand New. 268 pages. 9.20x6.10x0.63 inches. In Stock.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The intensive study of molecular events leading to cellular transformation in tissue culture or in intact organisms culminated in the identification of 100 or more genes that can be defined as oncogenes or tumor suppressor genes. Functionally, these genes can be divided into several classes, each involved in a different step in transmission of signals from the exterior of the cell to the nucleus. The first oncogenes to be biochemically character ized included membrane receptors for growth factors, growth factors themselves, protein kinases or small GTP binding proteins involved in signal transduction. Later, the development of techniques to study pro teins-DNA interaction in eucaryotes and the isolation and characterization of many promoter and enhancer sequences revealed that a number of the classical retroviral oncogenes were indeed transcription factors. In paral lel, the rapid progress in the identification and cloning of chromosomal translocations in human and animal malignancies and the increased reper toire of known transcription factors families revealed that many other transcription factors can playa critical role in cancer. A more recent devel opment concerns tumor suppressor genes. The realization that human tumors are frequently associated with a loss of function of one or several genes is also one of the landmarks of cancer research in the last 15 years. Again, as we will see below, some of these genes encode transcription factors. It is becoming increasingly difficult to cover in a single monograph all oncogenes and tumor suppressor genes.…

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The intensive study of molecular events leading to cellular transformation in tissue culture or in intact organisms culminated in the identification of 100 or more genes that can be defined as oncogenes or tumor suppressor genes. Functionally, these genes can be divided into several classes, each involved in a different step in transmission of signals from the exterior of the cell to the nucleus. The first oncogenes to be biochemically character ized included membrane receptors for growth factors, growth factors themselves, protein kinases or small GTP binding proteins involved in signal transduction. Later, the development of techniques to study pro teins-DNA interaction in eucaryotes and the isolation and characterization of many promoter and enhancer sequences revealed that a number of the classical retroviral oncogenes were indeed transcription factors. In paral lel, the rapid progress in the identification and cloning of chromosomal translocations in human and animal malignancies and the increased reper toire of known transcription factors families revealed that many other transcription factors can playa critical role in cancer. A more recent devel opment concerns tumor suppressor genes. The realization that human tumors are frequently associated with a loss of function of one or several genes is also one of the landmarks of cancer research in the last 15 years. Again, as we will see below, some of these genes encode transcription factors. It is becoming increasingly difficult to cover in a single monograph all oncogenes and tumor suppressor genes.…

Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Zustand: New. In English.

Zustand: New. In English.

Taschenbuch. Zustand: Neu. Oncogenes as Transcriptional Regulators | Retroviral Oncogenes | Moshe Yaniv (u. a.) | Taschenbuch | xiii | Englisch | 2012 | Birkhäuser | EAN 9783034898164 | Verantwortliche Person für die EU: Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. …

Taschenbuch. Zustand: Neu. Oncogenes as Transcriptional Regulators | Cell Cycle Regulators and Chromosomal Translocation | Moshe Yaniv (u. a.) | Taschenbuch | xiii | Englisch | 2012 | Birkhäuser | EAN 9783034898331 | Verantwortliche Person für die EU: Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.…

Hardcover. Zustand: Brand New. 162 pages. German language. 9.13x6.57x1.11 inches. In Stock.

Zustand: New.

Gebunden. Zustand: New.

Hardcover. Zustand: Brand New. 300 pages. German language. 9.29x6.30x0.79 inches. In Stock.

Zustand: Used. pp. 300.

Zustand: Used. pp. 162.

Zustand: Used. pp. 300.

Zustand: Used. pp. 162.

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering.

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering.