Itaru kojima (1 Ergebnisse)

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Since the 1970s, there has been much discussion about the 'glucoreceptor' and'substrate site' and which of these two is the dominant theory, but new findings on the glucose-sensing receptor have now shed new light on the 'glucoreceptor theory.'This volume reviews recent advances concerning the glucose-sensing receptor in pancreatic beta-cells.The history of research into pancreatic beta-cells is long and complex; accordingly, the first chapters present the history of this field and explain the hypothesis of insulin secretion mechanisms: 'glucoreceptor theory'. Subsequent chapters examine the function and activity ofthe glucose-sensing receptorin pancreatic beta-cells,such as identification, channel pathway, receptor signal and physiological role. Readers will gain a thorough understanding of the glucose-sensing receptorand glucose metabolism in pancreatic beta-cells, new insights into thepathophysiology of diabetes, and learn about new targets for the treatment of diabetes.…