Iain j mcewan (29 Ergebnisse)

hardcover. Zustand: Good. Ex- library copy with stamps and stickers.

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Paperback. Zustand: Brand New. 1st edition. 73 pages. 9.00x6.00x0.25 inches. In Stock.

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Zustand: Used. pp. 240.

Zustand: Used. pp. 240.

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Paperback. Zustand: Brand New. 210 pages. 9.00x6.00x0.39 inches. In Stock.

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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Thisvolume aims to describe acomplementary range of molecular, cell biological, and in vivo protocols used to investigatethe structure-function of nuclear receptors, together with experimentalapproaches that may lead to new drugs to selectively target nuclearreceptor-associated diseases. The NuclearReceptor Superfamily, Second Edition will benefit those starting out in thenuclear receptor research field as well as to more established researchers whowish to apply different methods to a particular receptor or research problem.Written in the highly successful Methods in Molecular Biology seriesformat, chapters include introductions to their respective topics, lists of thenecessary materials and reagents, step-by-step, readily reproducible laboratoryprotocols, and tips on troubleshooting and avoiding known pitfalls.Authoritativeand cutting-edge, The Nuclear ReceptorSuperfamily, Second Edition aims to ensure successful results in thefurther study of this vital field.…

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Nuclear Receptors focuses on the structural analysis of nuclear receptors from the initial work using isolated protein domains to the more recent exciting developments investigating the conformational shape of full-length receptor complexes. The book also reviews the structure of key nuclear receptor co-regulatory proteins. It brings together, for the first time, a comprehensive review of nuclear receptor structure and the importance of receptor conformation underpinning allosteric regulation by different ligands (hormone, drugs, DNA response elements, protein-protein interactions) and receptor activity.The nuclear receptor superfamily, including receptors for steroid hormones and non-steroid ligands, are pivotal to normal physiology, regulating processes as diverse as reproduction, metabolism, the immune system and brain development. The first members of the family were cloned over 25 years ago, which heralded in the idea of a superfamily of intracellular receptor proteins that bound small molecule ligands: classical steroid hormones, vitamins, fatty acids and other products of metabolism. These signals are then transmitted through multiprotein receptor-DNA complexes, leading to the regulation of target genes, often in a cell-selective manner. The cloning of the receptor cDNAs also ushered in an era of unparalleled analysis of the mechanisms of action of these ligand-activated transcription factors.…

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Nuclear Receptors focuses on the structural analysis of nuclear receptors from the initial work using isolated protein domains to the more recent exciting developments investigating the conformational shape of full-length receptor complexes. The book also reviews the structure of key nuclear receptor co-regulatory proteins. It brings together, for the first time, a comprehensive review of nuclear receptor structure and the importance of receptor conformation underpinning allosteric regulation by different ligands (hormone, drugs, DNA response elements, protein-protein interactions) and receptor activity.The nuclear receptor superfamily, including receptors for steroid hormones and non-steroid ligands, are pivotal to normal physiology, regulating processes as diverse as reproduction, metabolism, the immune system and brain development. The first members of the family were cloned over 25 years ago, which heralded in the idea of a superfamily of intracellular receptor proteins that bound small molecule ligands: classical steroid hormones, vitamins, fatty acids and other products of metabolism. These signals are then transmitted through multiprotein receptor-DNA complexes, leading to the regulation of target genes, often in a cell-selective manner. The cloning of the receptor cDNAs also ushered in an era of unparalleled analysis of the mechanisms of action of these ligand-activated transcription factors.…

Hardcover. Zustand: Brand New. 300 pages. 9.50x6.25x0.75 inches. In Stock.

Hardcover. Zustand: Brand New. 2nd edition. 10.00x7.25x0.75 inches. In Stock.

Taschenbuch. Zustand: Neu. The Nuclear Receptor Superfamily | Methods and Protocols | Mcewan | Taschenbuch | Methods in Molecular Biology | x | Englisch | 2018 | Springer | EAN 9781493981205 | Verantwortliche Person für die EU: Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. …

Taschenbuch. Zustand: Neu. Nuclear Receptors: From Structure to the Clinic | Iain J. McEwan (u. a.) | Taschenbuch | xi | Englisch | 2016 | Springer | EAN 9783319371283 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. …

Zustand: New. 2018. Softcover reprint of the original 2nd ed. 2016. paperback. . . . . . Books ship from the US and Ireland.

Zustand: New. Editor(s): McEwan, Iain J. Series: Methods in Molecular Biology. Num Pages: 260 pages, 12 black & white illustrations, 32 colour illustrations, 33 colour tables, biography. BIC Classification: PSD; PSF. Category: (G) General (US: Trade). Dimension: 254 x 178 x 16. Weight in Grams: 688. . 2016. 2 Rev ed. Hardback. . . . . Books ship from the US and Ireland. …

Zustand: Sehr gut. Zustand: Sehr gut | Seiten: 260 | Sprache: Englisch | Produktart: Bücher | This volume aims to describe a complementary range of molecular, cell biological, and in vivo protocols used to investigate the structure¿function of nuclear receptors, together with experimental approaches that may lead to new drugs to selectively target nuclear receptor-associated diseases. The Nuclear Receptor Superfamily, Second Edition will benefit those starting out in the nuclear receptor research field as well as to more established researchers who wish to apply different methods to a particular receptor or research problem. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, The Nuclear Receptor Superfamily, Second Edition aims to ensure successful results in the further study of this vital field.…

Taschenbuch. Zustand: Neu. The Nuclear Receptor Superfamily | Methods and Protocols | Iain J. McEwan | Taschenbuch | 240 S. | Englisch | 2010 | Humana | EAN 9781617379130 | Verantwortliche Person für die EU: Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. …

Zustand: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher | Nuclear Receptors focuses on the structural analysis of nuclear receptors from the initial work using isolated protein domains to the more recent exciting developments investigating the conformational shape of full-length receptor complexes. The book also reviews the structure of key nuclear receptor co-regulatory proteins. It brings together, for the first time, a comprehensive review of nuclear receptor structure and the importance of receptor conformation underpinning allosteric regulation by different ligands (hormone, drugs, DNA response elements, protein-protein interactions) and receptor activity.The nuclear receptor superfamily, including receptors for steroid hormones and non-steroid ligands, are pivotal to normal physiology, regulating processes as diverse as reproduction, metabolism, the immune system and brain development. The first members of the family were cloned over 25 years ago, which heralded in the idea of a superfamily of intracellular receptor proteins that bound small molecule ligands: classical steroid hormones, vitamins, fatty acids and other products of metabolism. These signals are then transmitted through multiprotein receptor-DNA complexes, leading to the regulation of target genes, often in a cell-selective manner. The cloning of the receptor cDNAs also ushered in an era of unparalleled analysis of the mechanisms of action of these ligand-activated transcription factors.    ¿.…

Zustand: New. Discusses the importance of steroid hormone receptors in the physiology and pathophysiology of various endocrine related diseases Provides state-of-the-art information based on key research findings in the field, along with hypotheses and .

Paperback. Zustand: Brand New. 240 pages. 10.98x8.27x0.66 inches. In Stock.

Paperback. Zustand: Brand New. 210 pages. 9.00x6.00x0.39 inches. In Stock.