George poste (78 Ergebnisse)

Hardcover. Zustand: Very Good. No Jacket. May have limited writing in cover pages. Pages are unmarked. ~ ThriftBooks: Read More, Spend Less.

Zustand: Fair. Volume 3. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. In fair condition, suitable as a study copy. No dust jacket. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,1750grams, ISBN:0720406234.…

gebundene Ausgabe. Zustand: Gut. 185 Seiten Das hier angebotene Buch stammt aus einer teilaufgelösten wissenschaftlichen Bibliothek und trägt die entsprechenden Kennzeichnungen (Rückenschild, Instituts-Stempel.); Schnitt und Einband sind etwas staubschmutzig; der Buchzustand ist ansonsten ordentlich und dem Alter entsprechend gut. Das Buch ist auf ENGLISCH. Sprache: Englisch Gewicht in Gramm: 550.…

gebundene Ausgabe. Zustand: Gut. 129 Seiten Das hier angebotene Buch stammt aus einer teilaufgelösten wissenschaftlichen Bibliothek und trägt die entsprechenden Kennzeichnungen (Rückenschild, Instituts-Stempel.); Schnitt und Einband sind etwas staubschmutzig; der Buchzustand ist ansonsten ordentlich und dem Alter entsprechend gut. Das Buch ist auf ENGLISCH. Sprache: Englisch Gewicht in Gramm: 550.…

Zustand: Very Good. 1987th Edition. Pages intact with possible writing/highlighting. Binding strong with minor wear. Dust jackets/supplements may not be included. Stock photo provided. Product includes identifying sticker. Better World Books: Buy Books. Do Good.

Zustand: Good. 194 pp., Hardcover, ex library, else text clean and binding tight. - If you are reading this, this item is actually (physically) in our stock and ready for shipment once ordered. We are not bookjackers. Buyer is responsible for any additional duties, taxes, or fees required by recipient's country.…

Zustand: Good. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. In good all round condition. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,950grams, ISBN:0306434636.

Cloth. Zustand: Near Fine. No Jacket. 1st Edition. 156 pages. Hardcover. Texts in English. Minimal shelfwear to the edges and associated faint rubbing to the covers. Lacking the printed paper wrapper. Otherwise, the binding is tight, the interior clean and unmarked. Bound in gilt-stamped red leatherette covered boards and published on the occasion of the exhibition held from September 23-December 16, 2000. Book.…

Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

156 pp.; 26.6 x 20.1 cm.; sewn bound; slipcase; black-and-white & color; edition size unknown; unsigned and unnumbered; offset-printed Exhibition catalogue / artist's book published in conjunction with show held September 23 - December 16, 2000. Book design mimics a medical journal. Content is heavy on necrology, autopsies [inclusive of many images related to the topic], crime scenes and gore galore. There's plenty of images of Hirst's work too. Embossed leatherette boards with printed paper sleeve. Very Good / Fine. Includes printed slipcase. Light yellowing of page edges with rubbing at edges of title page. Rubbing of cover corners and spine edges with light bumping of upper right corner of recto. 2 mm. rubbing of upper right corner, 1.5 cm. and 1.2 cm. rubbing/white staining of spine edge. 1.2, 1 mm., 1 cm., and 3 mm., rubbing/white staining of verso. Yellowing of slipcase edges and scratching with very light bumping of edges. 1.9 x 1.3 cm. partially removed pricing sticker on verso. Due to large size and weight of this publication additional shipping charges may be required for international orders.…

Zustand: New. In English.

Zustand: New. In English.

Zustand: New. In English.

Zustand: New. In English.

Zustand: New. In English.

Zustand: New. In English.

Zustand: New. In English.

Zustand: New. In English.

Zustand: New. In English.

Zustand: New. In English.

156 pages, fully illustrated. Hardback in a slipcase 20.3 x 26.7cms. ISBN: 1880154420. Text in English.

Paperback. Zustand: Brand New. reprint edition. 218 pages. 9.01x5.98x0.50 inches. In Stock.

Paperback. Zustand: Brand New. 162 pages. 10.00x7.01x0.38 inches. In Stock.

Paperback. Zustand: Brand New. reprint edition. 193 pages. 10.00x7.00x0.45 inches. In Stock.

Paperback. Zustand: Brand New. reprint edition. 252 pages. 10.00x7.00x0.60 inches. In Stock.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - I. Na+, K+, and H+ Transport.- 1 Molecular Properties of Voltage-Sensitive Sodium Channels.- II. Proton Pumps and Electrochemical Gradients.- 2 Studies of a Biological Energy Transducer: The lac Permease of Escherichia coli.- 3 The Erythrocyre Anion-Exchange Protein: Primary Structure Deduced from the cDNA Sequence and a Model for Its Arrangement within the Plasma Membrane.- 4 The Lysosomal Proton Pump.- 5 Ion PumpSy Ion Pathways, Ion Sites.- III. Calcium Channels and the Calcium Pump.- 6 Shifts between Modes of Calcium Channel Gating as a Basis for Pharmacologic Modulation of Calcium Influx in Cardiac, Neuronal, and Smooth-Muscle-Derived Cells.- 7 Chemical Pharmacology of Ca2+ Channel Ligands.- 8 Information Flow in the Calcium Messenger System.- 9 Neutrophil Activation, Polyphosphoinositide Hydrolysis, and the Guanine Nucleotide Regulatory Proteins.- IV. Inositol Lipids and the Calcium-Mediated Cellular Responses.- 10 Agonist-Dependent Phosphoinositide Metabolism: A Bifurcating Signal Pathway.- 11 Hormone-Induced Inositol Lipid Breakdown and Calcium-Mediated Cellular Responses in Liver.- 12 Comparison of the Na+ Pump and the Ouabain-Resistant K+ Transport System with Other Metal Ion Transport ATPases.- 13 Current Concepts of Tumor Promotion by Phorbol Esters and Related Compounds.- V. Cell Polarity and Membrane Transport Processes.- 14 Intracellular Protein Topogenesis.- 15 Analysis of Epithelial Cell Surface Polarity Development with Monoclonal Antibodies.- 16 Frequency and Time Domain Analysis of Epithelial Transport Regulation.- 17 The Epithelial Sodium Channel.- VI. Endocytosis as a Cell Transport Pathway.- 18 Uptake and Intracellular Processing of Cell Surface Receptors: Current Concepts and Prospects.- 19 Sorting in the Prelysosomal Compartment (CURL): Immunoelectron Microscopy of Receptors and Ligands.- 20 Mechanisms of Molecular Sorting in Endosomes.- 21 Transport of Protein Toxins across Cell Membranes.…

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The heat-shock proteins in E. coli are transiently overexpressed af ter shift to a higher growth temperature. The genes that encode the HSPs are preceded by promoters transcribed in vitro by a form of RNA poly 32 32 merase holoenzyme containing a 32-kd a subunit (Ea ). The a subunit is encoded by the rpoH (htpR) gene, previously identified as a positive 32 effector of the heat-shock response. Our evidence suggests that Ea is the enzyme that transcribes heat-shock genes at all temperatures. The level 32 of a may be regulated at several points: Accumulation of rpoH mRNA 32 is affected by temperature shift, a synthesis is regulated posttranscrip 32 tionally, and a is an unstable molecule with a tl/2 of 5 min. Many mu tations in the HSPs are shown to have defects in proteolysis. References Baker. T. A. , Grossman. A. D . . and Gross. C. A. , 1984, A gene regulating the heat shock response in Escherichia coli also affects proteolysis. Proc. Natl. A cad. Sci. US. A. 81:6779-6783. Bardwell, J. C. A . . and Craig, E. A . . 1984. Major heat shock gene of Drosophila and the Escherichia coli heat-inducible dnaK gene are homologous, Proc. Natl. Acad. Sci. US. A. 81:848-852. Bukhari. A. I. . and Zipser. D . . 1973, Mutants of Escherichia coli with a defect in the degradation of nonsense fragments, Nature New Bioi. 243:238-241. Charette. M. F. , Henderson, G. W. , and Markovitz, A.…

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The NATO Advanced Studies Institute series 'Targeting of Drugs' was originated in 1981. It is now a major international forum, held every two years in Cape Sounion, Greece, in which the present and the future of this important area of research in drug carriers is discussed in great depth. Four previous ASls of the series dealt with drug carriers of natural and synthetic origin, their interaction with the biological milieu and with ways by which the latter influences such interaction. The present book contains the proceedings of the 5th NATO ASI 'Targeting of Drugs: Optimization Strategies' held in Cape Sounion during 24 June-5 July, 1989. A logical sequel to the last one, the ASI deals with strategies by which milieu inter ference curtailing the function of drug carriers is circumvented or removed. We express our appreciation to Drs. R. Langer and E. Tomlinson for their valuable advice throughout the planning of the ASI and to Dr. G. Deliconstantinos who, as Chairman of the Local Committee contributed so effectively to its success. The ASI was held under the sponsorship of NATO Scientific Affairs Division and co-sponsored and generously financed by Smith Kline French Laboratories (now SmithKline Beecham), Philadelphia, USA. Financial assistance was also provided by CIBA Geigy (Horsham), Schering (West Berlin), Farmitalia Carlo Erba (Milan), Liposome Technology Inc. (Menlo Park), Pfizer (Sandwich), Dior (Paris), Syntex Research (Palo Alto), ICI Pharmaceuticals (Mereside), Boehringer (Mannheim) , Wyeth (Taplow), Merck Sharp Dohme (Rahway), Sandoz A.G. (Basle) and Lilly Research Centre Ltd.…

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - It is less than 80 years since John Newport Langley first proposed the role of 'receptive substances' as the site of drug action from his obser vations on the effects of nicotine and curare at the myoneural junction. The many advances in our understanding of receptor biology that have occurred during the intervening period mirror the extraordinary growth of knowledge in the biological sciences and in cell and molecular biology in particular. Receptor biology, in common with many other topics in contemporary biology, is on the threshold of a transition from being a descriptive, phenomenological discipline to one in which underlying mechanisms and regulatory principles can be defined with increasing pre cision. This change, together with the evolution of powerful analytical techniques and timely convergence of ideas from a number of previously separate fields of inquiry, is generating an increasingly unified theoretical and experimental framework for the study of receptor function. These themes, and the mood of anticipation that a real understanding of receptor function in health and disease is emerging, are reflected in in this volume, which summarizes the proceedings of the Sec the papers ond Smith Kline & French Research Symposium on New Horizons in Therapeutics held in Philadelphia in 1984.…

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - I. Advances in the Structural Analysis of Proteins.- 1 Dynamic Processes in Proteins by X-Ray Diffraction.- 2 Mass Spectrometric Methods for Determination of the Structure of Peptides and Proteins.- II. Protein Folding and Stability.- 3 Protein Folding and Stability.- 4 Genetic Analysis of Polypeptide Chain Folding and Misfolding in Vivo.- 5 Unfolding and Inactivation: Genetic and Chemical Approaches to the Stabilization of T4 Lysozyme and Human Interferon Gamma against Irreversible Thermal Denaturation.- III. Principles of Receptor Design and Regulation.- 6 Protein-Tyrosine Kinases and Their Substrates: Old Friends and New Faces.- IV. The Guanine Nucleotide Binding Protein Family.- 7 G Proteins: A Family of Signal-Transducing Molecules.- 8 Model of Signal Transduction by G Proteins: Roles of a Subunits and Dimers in Regulation of Ionic Channels and Adenylyl Cyclase.- 9 Structural Homologies in G-Binding Proteins.- V. Modeling and Structure Prediction in Macromolecules.- 10 Knowledge-Based Protein Modeling and the Design of Novel Molecules.- 11 Computer Simulation Methods as Applied to Site-Specific Mutations.- 12 Dihydrofolate Reductase: A Paradigm for Drug Design.- VI. Protein Engineering and Enzyme Design.- 13 Chemical Approaches to Protein Engineering.- 14 New Engineered Proteins for Use in Therapy and Vaccine Design.- 15 Receptor-Based Design of Dihydrofolate Reductase Inhibitors.- VII. Macromolecules and Targeted Drug Delivery.- 16 Control of the Biological Dispersion of Therapeutic Proteins.- 17 Antibody-Mediated Drug Delivery.- 18 Semisynthetic Catalytic Antibodies.- VIII. Strategies for Directed Mutagenesis of Proteins.- 19 Engineering Novel, Prolonged-Acting Insulins.- IX. Design of Novel Antiviral Agents and Vaccines.- 20 Studies on the Structure andFunction of Ubiquitin.- 21 Recognition at Membrane Surfaces: Influenza HA and Human HLA.…