Garrod david j (7 Ergebnisse)

Zustand: New. In English.

Gebunden. Zustand: New. The aim of The Adhesive Interaction of Cells has been to assemble a series of reviews by leading international experts embracing many of the most important recent developments in this rapidly expanding field. The purpose of all biological research is to u.

Buch. Zustand: Neu. Neuware - The aim of 'The Adhesive Interaction of Cells' has been to assemble a series of reviews by leading international experts embracing many of the most important recent developments in this rapidly expanding field. The purpose of all biological research is to understand the form and function of living organisms and, by comprehending the normal, to find explanations and remedies for the abnormal and for disease conditions. The molecules involved in cell adhesion are of fundamental importance to the structure and function of all multicellular organisms. In this book, the contributors focus on the systems of vertebrates, especially mammals, since these are most relevant to human disease. It would have been equally possible to concentrate on developmental processes and adhesion in lower organisms. A major function of adhesion molecules is to bind cells to each other or to the extracellular matrix, but they are much more than 'glue.' Adhesions in animal tissues must be dynamic-forming, persisting, or declining in regulated fashion- to facilitate the mobility and turnover of tissue cells. Moreover, the majority of adhesion molecules are transmembrane molecules and thus provide links between the cells and their surroundings. This gives rise to another major function of adhesion molecules, the capacity to transduce signals across the hydrophobic barrier imposed by the plasma membrane. Such signal transduction is crucially important to many aspects of cellular function including the regulation of cell motility, gene expression, and differentiation. The work in this book progresses through four sections. Part I discusses the four major families of adhesion molecules themselves, the integrins(Green and Humphries), the cadherins (Stappert and Kemler), the selectins (Tedder et al.) and the immunoglobulin superfamily (Simmons); part 2 considers junctional complexes involved in cell interactions: focal adhesions and adherens junctions (Ben Ze'ev), desmosomes (Garro.…

Zustand: New. In English.

Zustand: New. In English.

Zustand: New. pp. 428 52:B&W 6.14 x 9.21in or 234 x 156mm (Royal 8vo) Case Laminate on White w/Gloss Lam.

Zustand: Sehr gut. Zustand: Sehr gut | Seiten: 308 | Sprache: Englisch | Produktart: Bücher | This book presents a detailed summary of research on automatic layout of device-level analog circuits that was undertaken in the late 1980s and early 1990s at Carnegie Mellon University. We focus on the work behind the creation of the tools called KOAN and ANAGRAM II, which form part of the core of the CMU ACACIA analog CAD system. KOAN is a device placer for custom analog cells; ANANGRAM II a detailed area router for these analog cells. We strive to present the motivations behind the architecture of these tools, including detailed discussion of the subtle technology and circuit concerns that must be addressed in any successful analog or mixed-signal layout tool. Our approach in organizing the chapters of the book has been to present our algo­ rithms as a series of responses to these very real and very difficult analog layout problems. Finally, we present numerous examples of results generated by our algorithms. This research was supported in part by the Semiconductor Research Corpora­ tion, by the National Science Foundation, by Harris Semiconductor, and by the International Business Machines Corporation Resident Study Program. Finally, just for the record: John Cohn was the designer of the KOAN placer; David Garrod was the designer of the ANAGRAM II router (and its predeces­ sor, ANAGRAM I). This book was architected by all four authors, edited by John Cohn and Rob Rutenbar, and produced in finished form by John Cohn.…