fleming alexander sir (14 Ergebnisse)

Zustand: New. In.

Zustand: New. In.

Soft cover. Zustand: Good. stapled paperback, 8vo, 50pp, numerous photo illustrations, text clean and tight, no inscriptions, cover edges rubbed, Good condition.

c.294pp. 8vo. Original cloth, a little marked. Black and white plates; portrait frontis. Endpapers illustrated. A very good copy. First edition in English.

Soft cover. Zustand: Very Good. 1st Edition. First edition. 8vo. pp. 39; very good in the original limp paper wrappers, sightly rubbed. "Penicillin, its antecedents, its discovery, its applications and properties, its increasing production, are here described by the discoverer, who also touches upon the future of this and similar substances, and issues a powerful please for the speedy endowment of microbiological research" (blurb from inside front wrapper).

The Linacre Lecture 1946. Well-kept copy in tight binding; pages appear clean overall; jacket not price clipped. Used - Very Good. VG paperback in VG dust jacket.

ankfurt am Main, Büchergilde Gutenberg, 1863, 8°, 298 pp., orig. Leinenband mit Schutzumschlag.

hardcover. Zustand: Befriedigend. Seiten; Sprache: Deutsch Gewicht in Gramm: 1.

Kl.-8°. 8 Bl. Blockbuchheftung in blaugrüner Färbung, 3 Abb. OBrosch., OU. Vorträge von I.P. Gerasimov, E. Neef, A. Watznauer, K.E. Rothschuh. - Acta Historica Aus dem Inhalt: Aufbau der Stoffe. Atomare Geschosse und Geräte zur Erzeugung von Nach der zweiten engl. Auflage ins Deutsche übertragen von Prof. A. Noll und Johanna Sprache: deutsch.

Zustand: Bueno. Editorial Saturnino Calleja. Madrid s/a. E. Tela editorial con sobrecubierta. 440 pp. 22x14.

First Edition. Very good copy in the original gilt-blocked cloth. Spine bands and panel edges somewhat dulled and rubbed as with age. Spine uniformly sun-toned. SIGNED and inscribed by E.B. Fleming. Remains quite well-preserved overall. Physical description: x p., 1 l., 380 p. : illus., diagrs. ; 23 cm. Series: Butterworth's medical publications. Notes: Includes bibliographies. Subjects: Penicillin Therapeutic use; Penicillin Pharmacology; Penicillin; Anti-Bacterial Agents; Penicillin - antibiotics - pharmacology. 3 Kg.

4to, pp.12, with halftone illustrations in the text; stapled as issued.Second edition of Fleming's study announcing the discovery of penicillin, one of 250 copies which Fleming commissioned to be printed in 1944. The original offprint, issued in 1929 in 150 copies and liberally distributed by Fleming to the scientific community at large for the prompt furthering of much-needed research, is now virtually unobtainable. In 1928, while working with culture plates of Staphylococcus bacteria at StMary's Hospital in London, Fleming noticed that some of his plates had become contaminated with a mould and that the bacterial colonies in contact with it had become transparent or dissolved. He reported his discovery in 1929 in a paper published in the British Journal of experimental Pathology, naming the bactericidal substance 'penicillin' and proposing that an extract from it 'may be an efficient antiseptic for application to, or injection into, areas infected with penicillin-sensitive microbes'. However, as the substance proved too intractably unstable and Fleming remained unable to produce a stable and reliable drug, the paper failed to achieve an immediate impact. Only over a decade later, in 1940, did Ernst Chain and Howard Florey succeed in stabilising the drug and prescribing dosages for treatment. Provenance:The virologist Fred Himmelweit (19021977), who fled Germany in 1933, ending up in London with a job at the Wright-Fleming Institute at Saint Mary's Hospital, first under SirAlmroth Wright (18611947) and then under Fleming. There he studied viruses and the development of influenza vaccines, and eventually became director of the Department of Virus Research. Norman 799. See Garrison-Morton 1933; Heirs of Hippocrates 2320; One hundred Books famous in Medicine 96; and PMM 420a. Language: English.

London, Butterworth & Co., 1946, format in-8°, x pp + 380 pp, index. Original publisher's hardback (green cloth). No dustwrapper, spine a bit discoloured, some shelfwear, still a good/fine copy. No library markings.First edition.

London, Buttewrworth & Co. (Publishers), Ltd. Bell Yard, Temple Bar, July 1946, 8°, X, 380 pp., 59 Abbildungen, orig. Leinenband. First edition, first issue of the first printing of "the only book that Fleming prepared regarding his discovery of the antibiotic properties of penicillin". Norman Alexander Fleming made his discovery in 1928 and published his earliest paper on penicillin in 1929. But the substance was difficult to purify, and did not become available in large quantities until Howard Florey and Ernest Chain successfully mass-produced it at the beginning of the Second World War. It was during this conflict that penicillin proved its worth, successfully treating hundreds of thousands of Allied soldiers. This volume was published shortly after the war in the expectation that penicillin would soon be available commercially, but "there was not yet an authoritative British book for the guidance of the practitioner in its use" (preface). It contains an introduction by Fleming on his discovery of penicillin and 26 other essays on the history, manufacture, and clinical use of the drug by "experienced and eminent men" who were among the earliest to experiment with and prescribe it. A key work on the most significant medical breakthrough of the 20th-century, published while the therapy was still "very young and rapidly evolving". preface Printing and the Mind of Man 420; Garrison-Morton No.1933; Norman Libr. No. 800.