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Hardcover. Zustand: New. Contents: Preface. 1. Introduction: i. What is industrial steroid analysis? ii. Scope and limitations. 2. Methods used in steroid analysis: i. Spectroscopic methods and related techniques. ii. Chromatographic methods. iii. Protein binding methods. iv. Electroanalytical methods (potentiometry, polarography and voltammetry). 3. Structural elucidation of steroids: i. The role of structure elucidation studies in steroid research and production. ii. Synthetic products. iii. Natural products. iv. Structure elucidation of minor steroid components in mixtures. 4. Analytical control of the production of steroids: i. Analysis of raw materials. ii. In-process control in steroid syntheses. iii. Assays for the purity of bulk steroids. 5. Analytical control of steroid formulations: i. Analytical aspects of preformulation studies. ii. Analyses of steroid formulations. iii. Analytical problems associated with stability testing. 6. Determination of steroids in biological media: i. Determination of steroids in bioavailability and pharmacokinetic studies. ii. Health control of workers in steroid hormone production. Index. "This unique work describes the analytical chemistry of an important group of pharmaceutical compounds from the viewpoint of the pharmaceutical scientist. It reflects the view of an analytical chemist with 30 years practical and research experience in the pharmaceutical sciences, who has invited a team of specialist experts to collaborate in this exciting and challenging project. Investigating the spectroscopic, chromatographic, immunological and electroanalytical methods used in industrial steroid analysis, the book gives a balance of examples to reflect the special needs of pharmaceutical industrial scientists. Covering several aspects of the structure elucidation of steroids which occur in pharmaceutics, the authors cover a range of new synthetic products not previously discussed in literate for. The authors present analytical problems associated with the investigation of bulk steroid drugs, dealing with the starting materials of steroid semi-synthesis, with examples of in-process-control merit. They deal with preformulation studies, discuss assay and stability methods, and determine steroids in biological samples from an analytical viewpoint as well as in terms of health control in steroid production.".