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No jacket. Zustand: Bon. Ancien livre de bibliothèque. Légères traces d'usure sur la couverture. Sans jaquette. Edition 1964. Ammareal reverse jusqu'à 15% du prix net de cet article à des organisations caritatives. ENGLISH DESCRIPTION Book Condition: Used, Good. Former library book. Slight signs of wear on the cover. No dust jacket. Edition 1964. Ammareal gives back up to 15% of this item's net price to charity organizations.…

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Hardcover. Zustand: Very Good. Hardcover (no jacket). One or two minor marks on page block; previous owner's name penned on FEP; content is clear throughout on sound pages. TS. Used.

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Hardcover. Zustand: Very Good. Hardcover in very good condition. No jacket. Previous owner's name penned on FEP. Pages are clean and text is clear throughout. HCW. Used.

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Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Parameters such as membrane transport, metabolism and protein incorporation govern the fate of amino acids in living tissue. Is it possible to use positron tomography to measure some of them, and what is their meaning in normal and pathological situations These questions have been addressed for a long time and no satisfactory answer has yet been given.This book, which derives from an EEC workshop organized in the frame of the Concerted Action on `PET Investigation of Cellular Regeneration and Degeneration', held in Lyon in February 1992, gives the present state of knowledge in this field based on the most recent studies. Contributions from 24 leading European and American scientists are presented and discussed in the following four parts: biochemistry and animal studies; amino acids labelling with positron emittors, quality control and metabolites measurement; kinetic modelling of amino acids transport, metabolism, and protein incorporation; clinical use of amino acids. This book will aid and interest biochemists, radiochemists, pharmacologists, neurologists, oncologists and medical imaging scientists.…

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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Parameters such as membrane transport, metabolism and protein incorporation govern the fate of amino acids in living tissue. Is it possible to use positron tomography to measure some of them, and what is their meaning in normal and pathological situations These questions have been addressed for a long time and no satisfactory answer has yet been given. This book, which derives from an EEC workshop organized in the frame of the Concerted Action on `PET Investigation of Cellular Regeneration and Degeneration', held in Lyon in February 1992, gives the present state of knowledge in this field based on the most recent studies. Contributions from 24 leading European and American scientists are presented and discussed in the following four parts: biochemistry and animal studies; amino acids labelling with positron emittors, quality control and metabolites measurement; kinetic modelling of amino acids transport, metabolism, and protein incorporation; clinical use of amino acids. This book will aid and interest biochemists, radiochemists, pharmacologists, neurologists, oncologists and medical imaging scientists.…

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Imaging of the Dopaminergic system in the human brain with the in vivo use of Positron Emis sion Tomography has emerged in the late 1980s as a tool of major importance in Clinical Neuros ciences and Pharmacology. The last few years have witnessed the rapid development of new radiotracers specific to receptors, reuptake sites and enzymes of the dopamine system; the application of these radiotracers has led to major breakthroughs in the pathophysiology and therapy of movement disorders and schizophrenic-like psychoses. This book is the first to collect, in a single volume, state-of-the-art contributions to the various aspects of this research. Its contents address methodological issues related to the design, labelling, quantitative imaging and compartmental modelisation of radioligands of the post-synaptic, pre-synaptic and enzyme sites of the dopamine system and to their use in clinical research in the fields of Parkinson's disease as well as other movement disorders, psychoses and neuroleptic receptor occupancy. The chapters were written by leading European scientists in the field of Positron Emission Tomography, gathered together in Caen (France, November 1990) under the aegis of the EEC Concerted Action on 'PET Investigations of Cellular Regeneration and Degeneration. This book provides a current and comprehensive overview on PET studies of the brain dopamine system which should aid and interest neurologists, psychiatrists, pharmacologists and medical imaging scientists. J. C. Baron D. Comar L. Farde J. L. Martinot B. Mazoyer August 1991 ix LIST OF CONTRffiUTORS Dr Yves Agid DrL.…

Paperback. Zustand: Brand New. 208 pages. 9.25x6.10x0.51 inches. In Stock.

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Buch. Zustand: Neu. Neuware - 1. Neuroanatomy of dopaminergic system in the human brain.- 2. Radioligands for PET studies of D2-receptors: butyrophenone and ergot derivatives.- 3. Radioligands for dopamine receptor PET studies: benzamides and ligands for dopamine D-1 receptors.- 4. Monoamine precursors in PET research - biochemical issues and functional significance.- 5. Quantitation problems in positron emission tomography (PET) as applied to the kinetic analysis of the striatum dopamine data.- 6. Investigation of the dopamine system with positron emission tomography: general issues in modeling.- 7. Modelisation: application to the D2 receptors.- 8. [18F] Fluorodopa uptake in brain.- 9. Dopamine reuptake sites: the issues.- 10. Movement disorders: the clinical issues.- 11. Non-human primate models of dopamine system disorders: understanding neurodegenerative diseases and testing new therapeutic strategies.- 12. The dopamine system and mental disorders: clinical and psychopharmacological overview.- 13. D2 dopamine receptors and schizophrenia.- 14. The assessment of central D2-dopanvne receptor occupancy with positron emission tomography in long-term medicated schizophrenic patients.- 15. Measurement of dopamine receptor occupancy: clinical issues.…

Hardcover. Zustand: Brand New. 208 pages. 9.57x6.50x0.55 inches. In Stock.

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Hardcover. Zustand: Brand New. 288 pages. 9.75x6.50x0.75 inches. In Stock.

Gebunden. Zustand: New. Parameters such as membrane transport, metabolism and protein incorporation govern the fate of amino acids in living tissue. Is it possible to use positron tomography to measure some of them, and what is their meaning in normal and pathological situations? .

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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Can drug development and evaluation be improved by the use of positron emission tomography (PET) PET is now well established and many PET centres participate in networks that warrant the quality of their research. PET allows one to follow the effect of a drug on a variety of patients' metabolic parameters. In addition, PET may be used to follow the fate in vivo of a compound, allowing visualisation of its binding to specific receptors and a direct study of the mechanism of drug action in normal and pathological situations. The book shows the fields in which PET offers new and unique information for the development of drugs (conception, toxicity, pharmacokinetics and metabolism, clinical research, and relations between clinical and biological effects) and evaluates fields in which PET may shorten the development time of drugs. Audience: Professionals in the pharmaceutical industry in all areas of drug discovery and pharmacology, pre-clinical testing, pharmacokinetics and metabolism, clinical evaluation, registration and regulatory affairs. Government health authority representatives who assess data and documentation on new drug development and radiopharmaceuticals. Academic experts concerned with any of these areas.…

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Can drug development and evaluation be improved by the use of positron emission tomography (PET) PET is now well established and many PET centres participate in networks that warrant the quality of their research. PET allows one to follow the effect of a drug on a variety of patients' metabolic parameters. In addition, PET may be used to follow the fate in vivo of a compound, allowing visualisation of its binding to specific receptors and a direct study of the mechanism of drug action in normal and pathological situations. The book shows the fields in which PET offers new and unique information for the development of drugs (conception, toxicity, pharmacokinetics and metabolism, clinical research, and relations between clinical and biological effects) and evaluates fields in which PET may shorten the development time of drugs. Audience: Professionals in the pharmaceutical industry in all areas of drug discovery and pharmacology, pre-clinical testing, pharmacokinetics and metabolism, clinical evaluation, registration and regulatory affairs. Government health authority representatives who assess data and documentation on new drug development and radiopharmaceuticals. Academic experts concerned with any of these areas.…

Zustand: New. pp. 268.

Paperback. Zustand: Brand New. reprint edition. 372 pages. 9.45x6.30x0.88 inches. In Stock.

Hardcover. Zustand: Brand New. 1st edition. 360 pages. 10.00x7.00x1.00 inches. In Stock.