Claude gaultier (10 Ergebnisse)
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Zustand: New. pp. xxxii + 311.
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Zustand: Sehr gut. Zustand: Sehr gut | Seiten: 360 | Sprache: Englisch | Produktart: Bücher | Bringing together top-level contributions on all aspects of the subject, this book provides an overview of the recent advances in the genetics of respiratory control in health and disease. It also shows how combined studies in humans an…d mouse models have helped to improve our understanding of the mechanisms that underlie genetically determined respiratory control disorders with the goal of developing new therapeutic interventions.
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Taschenbuch. Zustand: Neu. Genetic Basis for Respiratory Control Disorders | Claude Gaultier | Taschenbuch | xxxi | Englisch | 2014 | Springer | EAN 9781489988928 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
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Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Genetic Basis for Respiratory Control Disorders provides an overview of the recent knowledge of the genetic factors underlying respiratory control disorders, an emerging field in respiratory biology. Identifying genes involved in respiratory control is cruc…ial for understanding human diseases characterized by abnormal respiratory control, such as Prader-Willi syndrome, Rett syndrome, congenital central hypoventilation syndrome (CCHS), obstructive sleep apnea syndrome (OSAS), central sleep apnea syndrome, apneas of prematurity and sudden infant death syndrome (SIDS). Furthermore, genetic factors play a key role in respiratory control adaptation in health and disease, most notably in the respiratory response to intermittent hypoxia.The objective of the book is to supply state-of-the-art contributions about all aspects of respiratory control genetics, from the molecular to the system level. The book aims to review the full spectrum of available knowledge, which starts with early physiological studies in health and disease in humans and studies in rodents that suggested a hereditary component to respiratory control. The spectrum extends to recent work elucidating crucial molecular aspects of respiratory control development, from early embryonic specifications in the neural tube to the function of respiratory rhythm generators.Developmental programs and gene expression profiles of different neuron types in the respiratory-control neuronal network have been characterized, together with their control by specific sets of transcription factors. In mice, targeted inactivation of several transcription factors disrupts the development of specific respiratory-neuron groups and causes abnormal respiratory phenotypes. These effects are described in detail in the book, with . a special attention to was given to the role of the transcription factor Phox2b. The developmental and respiratory phenotypes in newborn mice with Phox2b gene deletion and in vitro investigations of human mutated PHOX2B proteins have shed light on the pathogenesis of CCHS. Respiratory control abnormalities in necdin-null mice and in mice lacking Mecp2 gene have provided new insights into the developmental origins of the respiratory disorders seen in Prader-Willi and Rett syndromes, respectively. Current genetic data in complex and multi-factorial respiratory disorders, including SIDS and OSAS, are described.Genetic Basis for Respiratory Control Disorders emphasizes the potent synergy between human studies and mouse models of genetic disorders underlying respiratory control anomalies. The overview of current research presented in this book opens up the field to the development of new therapeutic strategies, especially in newborns and infants, who are the primary target of respiratory control disorders. This book is addressed to pediatricians, neonatologists, pulmonologists, respiratory physiologists as well as geneticists.
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Genetic Basis for Respiratory Control Disorders provides an overview of the recent knowledge of the genetic factors underlying respiratory control disorders, an emerging field in respiratory biology. Identifying genes involved in respiratory control…is crucial for understanding human diseases characterized by abnormal respiratory control, such as Prader-Willi syndrome, Rett syndrome, congenital central hypoventilation syndrome (CCHS), obstructive sleep apnea syndrome (OSAS), central sleep apnea syndrome, apneas of prematurity and sudden infant death syndrome (SIDS). Furthermore, genetic factors play a key role in respiratory control adaptation in health and disease, most notably in the respiratory response to intermittent hypoxia.The objective of the book is to supply state-of-the-art contributions about all aspects of respiratory control genetics, from the molecular to the system level. The book aims to review the full spectrum of available knowledge, which starts with early physiological studies in health and disease in humans and studies in rodents that suggested a hereditary component to respiratory control. The spectrum extends to recent work elucidating crucial molecular aspects of respiratory control development, from early embryonic specifications in the neural tube to the function of respiratory rhythm generators.Developmental programs and gene expression profiles of different neuron types in the respiratory-control neuronal network have been characterized, together with their control by specific sets of transcription factors. In mice, targeted inactivation of several transcription factors disrupts the development of specific respiratory-neuron groups and causes abnormal respiratory phenotypes. These effects are described in detail in the book, with . a special attention to was given to the role of the transcription factor Phox2b. The developmental and respiratory phenotypes in newborn mice with Phox2b gene deletion and in vitro investigations of human mutated PHOX2B proteins have shed light on the pathogenesis of CCHS. Respiratory control abnormalities in necdin-null mice and in mice lacking Mecp2 gene have provided new insights into the developmental origins of the respiratory disorders seen in Prader-Willi and Rett syndromes, respectively. Current genetic data in complex and multi-factorial respiratory disorders, including SIDS and OSAS, are described.Genetic Basis for Respiratory Control Disorders emphasizes the potent synergy between human studies and mouse models of genetic disorders underlying respiratory control anomalies. The overview of current research presented in this book opens up the field to the development of new therapeutic strategies, especially in newborns and infants, who are the primary target of respiratory control disorders. This book is addressed to pediatricians, neonatologists, pulmonologists, respiratory physiologists as well as geneticists.
Weitere BilderLes peintures sacrées sur la Bible. Par le R. Père Antoine Girard, de la Compagnie de Jésus. Dédiées a? la reyne mere. Troisiesme Edition.
Girard, Antoine ; Gilles Rousselet; Claude Vignon,; Melchior Tavernier; Léonard Gaultier,;Jan Ziarnko; Claude Mellan; Jean Messager,;Veuve d'Antoine de Sommaville
Verlag: Paris, Chez la veuve Antoine de Sommaville., 1665
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In den WarenkorbZustand: Good. Folio. 23.5 x 36.5 cm. Qtr. calf with gilt spine and marbled boards. MIssing piece on title page.2 parties ([36]-475-[1 bl.] ; 23-[1 bl.] p.) : ill. gr.s.c. ; In-fol.OCLC 491909140.Discours historique de la vie, de la passion et de la mort de Nostre Seigneur Jésus Christ (p. 1-23, 2 partie)Notes:Frontispice gravé…sur cuivre par Gilles Rousselet d'après Claude Vignon ; 69 illustrations dans le texte avec leur légende, gravées sur cuivre par différents graveurs dont Melchior Tavernier, Ziarnko, Léonard Gaultier, Claude Mellan et imprimées pour certaines par Jean Messager ; elles sont reproduites d'après les images de la Saincte Bible françoise de Frizon (1621) ; bandeaux, lettrines, culs de lampe.GIRARD (R.E.P. Antoine) - Les peintures sacrées sur la bible. ; in-folio, page de titre imprimée, XXXII-475 pp., reliure du 19ème siècle, demi-veau box, dos à 5 nerfs, pièce de titre en maroquin rouge et de tomaison en maroquin vert. Frontispice de Vignon gravé à l'eau-forte par Rousselet, 69 gravures sur acier (la plupart à demi-page, certaines par Messager et Gaultier). Édition originale.
