Boquet a c (2 Ergebnisse)

Zustand: Good. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. In good all round condition. Dust Jacket in fair condition. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,550grams, ISBN.…

Couverture souple. Zustand: Très bon. Edition originale. 1 vol. in-8 (23 x 15.5 cm), 250, (1) pp., X planches hors-texte, (40) pp. (extrait du catalogue de l'éditeur), broché, très petit manque marginal à un feuillet, exemplaire en partie non coupé et en très bon état. Edition originale rare. Il s'agit du premier ouvrage complet sur le sujet, exposant les méthodes et les résultats d'un quart de siècle de travaux, et dans lequel "sont groupés, méthodiquement et clairement, tous les documents sur lesquels est basée la vaccination par le B.C.G. (bacille Calmette-Guérin)" (P. Lereboullet). Le BCG est le vaccin le plus utilisé dans le monde ; il s'est révélé efficace non seulement pour prévenir la tuberculose mais aussi pour stimuler une réponse immunitaire antitumorale (immunothérapie par instillation intravésicale dans les cancers superficiels de la vessie) et sans doute offrir une protection contre diverses infections non mycobactériennes. Cet ouvrage est divisé en quatre parties : Bref exposé des diverses tentatives de vaccination antituberculeuse effectuées depuis la découverte du bacille de Koch ; Le "BCG", son étude expérimentale ; Le "BCG" - entretien des cultures - préparation des émulsions vaccinales - étude biochimique ; La vaccination prévenive des enfants nouveau-nés contre la tuberculose par le "BCG". REFERENCES: Garrison & Morton, 11994: "A 250-page monograph, with bibliographical references, on the development of the BCG vaccine from M. bovis, from 1909 to 1927 by the scientists involved."; Silverstein AM: A history of immunology, p. 336: "important book in immunology"; Lechevalier HA & Solotorovsky M: Three centuries of microbiology, pp. 229-234; Kaufmann SHE: Vaccine Development Against Tuberculosis Over the Last 140 Years: Failure as Part of Success: "The 30 years between 1890, when Koch had first announced his vaccine against TB, and 1921, when Albert Calmette (1863-1933) and Camille Guérin (1872-1961) administered BCG to a human neonate for the first time, were characterized by the development and clinical testing of different vaccine types including subunit vaccines, inactivated vaccines and live whole-cell vaccines with only one final success: BCG (Calmette et al., 1927). This vaccine was created following the principles of Pasteur to attenuate the causative agent of disease by culture conditions which caused loss of virulence factors."; Plotkin S: History of vaccination: "The more powerful technique of serial cultivation of a pathogen in vitro or in inhabitual hosts originated with Calmette and Guérin, who passaged bovine tuberculosis bacteria 230 times in artificial media to obtain an attenuated strain to protect against human tuberculosis."; Rodrigues CMC et al.: Impact of Vaccines; Health, Economic and Social Perspectives: "Alternative methods of attenuation using serial passage of Mycobacterium bovis led to the live Bacille Calmette-Guerin (BCG) (Calmette, 1927) vaccine, still in use today for the prevention of tuberculosis."; Luca S &Mihaescu T: History of BCG Vaccine, Maedica (Bucur). 2013 Mar;8(1):53-58; Rees AR: A New History of Vaccines for Infectious Diseases, p. 163; Lobo N et al.: 100 years of Bacillus Calmette-Guérin immunotherapy: from cattle to COVID-19, Nat Rev Urol. 2021 Oct;18(10):611-622.…