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Zustand: New. pp. 250.

Zustand: New. In.

Zustand: New. Examines the evolutionary origins and consequences of the extracellular matrix Delivers the first book to quantitatively treat the extracellular matrix as a multiscale system Presents problems and a set of computational laboratory.

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The lung is a complex multiscale organ that serves as the primary interface between the environment and the tissues of the body. Homeostatic maintenance of lung function throughout life is essential for health. While failure of lung homeostasis underlies many of the most common chronic diseases that afflict mankind, the precise pathophysiologic mechanisms involved are often unclear. Investigative techniques such as microscopic imaging and atomic force microscopy are providing new insights into lung tissue properties at the micro scale. It nevertheless remains to be seen how this growing body of information can be integrated into a comprehensive picture of the lung. Mathematical and computational modeling has emerged as an essential tool for gaining such a holistic understanding. This book introduces the reader to the art of modeling as a means of linking lung structure to function over multiple length scales from the intracellular level to that of the whole organ, with specific attention given to the pathophysiology of a number of common lung diseases and aging.

Hardcover. Zustand: Brand New. 300 pages. 9.25x6.10x9.21 inches. In Stock.

Taschenbuch. Zustand: Neu. Neuware - Structure and Function of the Extracellular Matrix: A Multiscale Quantitative Approach introduces biomechanics and biophysics with applications to understand the biological function of the extracellular matrix in health and disease. A general multiscale approach is followed by investigating behavior from the scale of single molecules, through fibrils and fibers, to tissues of various organ systems. Through mathematical models and structural information, quantitative description of the extracellular matrix function is derived with tissue specific details. The book introduces the properties and organization of extracellular matrix components and quantitative models of the matrix, and guides the reader through predicting functional properties.