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gebundene Ausgabe. Zustand: Gut. 260 Seiten; Das hier angebotene Buch stammt aus einer teilaufgelösten wissenschaftlichen Bibliothek und trägt die entsprechenden Kennzeichnungen (Rückenschild, Instituts-Stempel.); leichte altersbedingte Anbräunung des Papiers; der Buchzustand ist ansonsten ordentlich und dem Alter entsprechend gut. In ENGLISCHER Sprache. Sprache: Englisch Gewicht in Gramm: 520.…

Zustand: New. In English.

Zustand: New. In English.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume of Current Topics in Microbiology and Immunology was planned in parallel with an EM BO workshop on cell-cell Interactions in Leukocyte Homing and Differentiation held at the Basel Institute for Immunology in November 1992, and many of the workshop speakers have contributed to it. Cell adhesion is one of the most dynamic fields of biological research and presented in this book is the current knowledge on the structure and function of the major families of cell adhesion molecules-the integrins, the selectins, the immunoglobulin superfamily, and CD44. Complex interactions between the members of these families mediate diverse adhesion functions, including leukocyte-leukocyte interactions, lymphocyte homing, inflammation, and lymphocyte-stromal cell interaction during hematopoiesis. A great deal of emphasis is placed on the regulatory elements that control the expression and function of adhesion molecules. Cytokines not only induce the expression of certain adhesion molecules, but may also modify their functional status. For instance, the integrins exist in either an inactive nonfunctional form or an active functional form, and a number of intracellular or extracellular stimuli modify integrin function. This is particularly important during leukocyte binding to endothelium and transendothelial migration, which proceeds through a cascade of adhesion events. Although cell adhesion molecules play an important role in many processes, this book concentrates on their role within the immune system. A number of chapters discuss the migration of lymphocytes between hematopoietic organs such as the thymus, lymph nodes, Peyer's patches, and spleen.…

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The chicken is a useful model for research into the basic features of immunology because its immune system functions in a way similar to that of human beings and because the chicken embryo is easily accessed experimentally. This book is a collection of comprehen sive articles updating chicken embryogenesis and immunology. It is now clear that it is possible to produce transgenic chickens by embryonic stem cell manipulation and transfer into the oocyte. Alternatively, the chick offers us the possibility of producing somatic chimeras by manipulating embryonic cells at the primitive streak or earlier stages. Working with later em bryos, we can learn the principles involved in the positioning of organ anlagen such as the limb bud. It is shown in this book that these structures are formed by appropriate cell and tissue arrangements driven by molecular factors. Work on the chicken has contributed substantially to our understanding of basic immunology, including the graft-vs. -host reaction, the clonal reactivity of immunocompetent cells, sepa ration of the T and B cell lineages, somatic diversification of the B cell repertoire by immunoglobulin (Ig) class switching, anti body diversification, Ig gene conversion, and the origin of the hematopoietic stem cell precursor of lymphoid and myeloid cells. Hematopoietic stem cells emerge successively from sev eral embryonic sites such as the yolk sac, the aorta, and the mesentery near the aorta.…

Paperback. Zustand: Brand New. reprint edition. 269 pages. 9.25x6.10x0.60 inches. In Stock.

Paperback. Zustand: Brand New. reprint edition. 281 pages. 8.75x6.00x0.75 inches. In Stock.

Zustand: Sehr gut. Zustand: Sehr gut | Seiten: 269 | Sprache: Englisch | Produktart: Bücher | Keine Beschreibung verfügbar.