Avigdor shafferman (24 Ergebnisse)
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Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Molecular Polymorphism: Biosynthesis of the Molecular Forms of Acetylcholinesterase (J. Massoulie et al.). Molecular Organization of Recombinant Human Acetylcholinesterase (B. Velan et al.). Nematode Acetylcholinesterases (M. Arpagaus et al.). Structure Fun…ction Relationship: Three Dimensional Structure of Acetylcholinesterase (J.L. Sussman et al.) Structural Analysis of Acetylcholinesterase Ammonium Binding Sites (I. Schalk et al.). Structural Investigations of Acetylcholinesterase (F. Hucho et al.). Physiological Role and Clinical Applications: Factors Influencing Acetylcholinesterase Regulation in Slow and Fast Skeletal Muscles (J. Sketelj et al.). Towards a Functional Analysis of Cholinesterases in Neurogenesis (P.G. Layer). Acetylcholinesterase as a Modulatory Neuroprotein and its Influence on Motor Control (S.A. Greenfield). 28 additional articles. Index.
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Taschenbuch. Zustand: Neu. Multidisciplinary Approaches to Cholinesterase Functions | Avigdor Shafferman (u. a.) | Taschenbuch | xvi | Englisch | 2012 | Springer | EAN 9781461363286 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter:… preigu.
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Acetylcholinesterase plays a key role in cholinergic transnnSSlOn. By rapid hydrolysis of the neurotransmitter acetylcholine the enzyme terminates the chemical impluse, thereby allowing rapid repetitive responses. Inhibitors of cholinesterases have i…mportant applications in agriculture - pest control, and in medicine - treatment of various disorders such as myasthenia gravis, glaucoma and management of Alzheimer's disease. These are some of the reasons for the special attraction of scientists from multiple disciplines such as neurobiology, pharmacology, chemistry, biochemistry, molecular biology and biotechnology to cholinesterase research. We have been fortunate to organize the 36th OHOLO conference on Multidisciplinary Approaches to Cholinesterase Functions at a time when this field of research is bursting with new concepts and ideas, brought about by the recent structural resolution of the catalytic subunit of acetylcholinesterase and by application of methodologies related to molecular genetics and protein engineering. This volume summarizes most of the important advances resulting from these developments as reflected in the OHOLO meeting.
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Gebunden. Zustand: New. Molecular Polymorphism: Biosynthesis of the Molecular Forms of Acetylcholinesterase (J. Massoulie et al.). Molecular Organization of Recombinant Human Acetylcholinesterase (B. Velan et al.). Nematode Acetylcholinesterases (M. Arpagaus et al.). Structure Fun.
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Zustand: New. pp. 310 23 Illus.
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Sprache: Englisch
Verlag: Springer, 2011
Serie: Buch 74 von 544 - Advances in Experimental Medicine and Biology
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Vaccination is one of the most efficient and cost effective methods of promoting human health and has been in clinical use for at least 200 years. Nevertheless, infectious diseases continue to constitute a constant threat to the well being of humanit…y. Common pathogens, once believed to be under control, acquire increased virulence and resistance to drugs, while exotic microorganisms emerged from hidden reservoirs to cause yet incurable diseases in humans. These changes, together with epidemic outbreaks related to political and socio-economic instabilities, increase the needs for the development of new, advanced vaccines. In this volume, devoted to the proceedings of the 39th OHOLO Conference, we present some of the recent strategies for the design and production of novel vaccines. The advent of recombinant DNA technology has stimulated the production of several subunit vaccines. In spite of the obvious advantages to this approach, the limited immuno genicity of many subunit candidates has hindered their development. Strategies to enhance the immunogenicity of subunit vaccines is therefore critical. Several approaches toward this goal, including design of novel adjuvants and delivery systems as well as design of advantageous carriers, are presented here. Among the carriers evaluated here are polypep tides (flagellin, HBV core antigen, J3-galactosidase), attenuated virions (Vaccinia, Sindbis), and nonpathogenic licensed bacteria (Salmonella).
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Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Vaccination is one of the most efficient and cost effective methods of promoting human health and has been in clinical use for at least 200 years. Nevertheless, infectious diseases continue to constitute a constant threat to the well being of humanity. Comm…on pathogens, once believed to be under control, acquire increased virulence and resistance to drugs, while exotic microorganisms emerged from hidden reservoirs to cause yet incurable diseases in humans. These changes, together with epidemic outbreaks related to political and socio-economic instabilities, increase the needs for the development of new, advanced vaccines. In this volume, devoted to the proceedings of the 39th OHOLO Conference, we present some of the recent strategies for the design and production of novel vaccines. The advent of recombinant DNA technology has stimulated the production of several subunit vaccines. In spite of the obvious advantages to this approach, the limited immuno genicity of many subunit candidates has hindered their development. Strategies to enhance the immunogenicity of subunit vaccines is therefore critical. Several approaches toward this goal, including design of novel adjuvants and delivery systems as well as design of advantageous carriers, are presented here. Among the carriers evaluated here are polypep tides (flagellin, HBV core antigen, J3-galactosidase), attenuated virions (Vaccinia, Sindbis), and nonpathogenic licensed bacteria (Salmonella).
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Sprache: Englisch
Verlag: Springer Netherlands, 2011
Serie: Buch 74 von 544 - Advances in Experimental Medicine and Biology
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Zustand: Hervorragend. Zustand: Hervorragend | Sprache: Englisch | Produktart: Bücher | The title "Nano Biotechnology for Biomedical and Diagnostics Research" will address research aspects related to nanomaterial in imaging and biological research, nanomaterials as a biosensing tool, DNA nanotechnology, nanomaterials for drug de…livery, medicinal and therapeutic application and cytotoxicity of nanomaterials. These topics will be covered by 16 different manuscripts. Amongst the authors that will contribute to the book are major scientific leaders such as S. Weiss - UCLA, I. Willner, and G. Golomb ¿ HUJI, S. Esener - UCSD, E.C. Simmel - Tech. Univ. Munchen, I. Medintz ¿ NRL, N. Hildebrandt - Université Paris and more. The manuscripts in the book intend to present specifically biological, diagnostics and medical problems with their potential solution by nano technology or materials. In this respect this book is unique, since it would arise from the biological problems to the nano technology possible solution and not vice versa.
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Taschenbuch. Zustand: Neu. The Challenge of Highly Pathogenic Microorganisms | Mechanisms of Virulence and Novel Medical Countermeasures | Avigdor Shafferman (u. a.) | Taschenbuch | xviii | Englisch | 2014 | Springer | EAN 9789400799110 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelber…g, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
Sprache: Englisch
Verlag: Springer Netherlands, Springer Netherlands, 2011
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Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The title 'Nano Biotechnology for Biomedical and Diagnostics Research' will address research aspects related to nanomaterial in imaging and biological research, nanomaterials as a biosensing tool, DNA nanotechnology, nanomaterials for drug delivery, medicin…al and therapeutic application and cytotoxicity of nanomaterials. These topics will be covered by 16 different manuscripts. Amongst the authors that will contribute to the book are major scientific leaders such as S. Weiss - UCLA, I. Willner, and G. Golomb - HUJI, S. Esener - UCSD, E.C. Simmel - Tech. Univ. Munchen, I. Medintz - NRL, N. Hildebrandt - Université Paris and more. The manuscripts in the book intend to present specifically biological, diagnostics and medical problems with their potential solution by nano technology or materials. In this respect this book is unique, since it would arise from the biological problems to the nano technology possible solution and not vice versa.
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Zustand: Sehr gut. Zustand: Sehr gut | Seiten: 332 | Sprache: Englisch | Produktart: Bücher | The OHOLO conferences are sponsored by the Israel Institute for Biological Research and take their name from the site of the ?rst meeting on the shores of Lake Kinnereth. The purpose of these meetings is, as it was at their inception ov…er 50 years ago, ¿to foster interdisciplinary communication between scientists in Israel, and to provide added stimulus by the participation of invited scientists from abroad¿. The core of the organizers of the OHOLO conferences are scientists from the Israel Institute for Biological Research. From time to time a particular OHOLO conference cooperates with an international scienti?c organization. The present 46th OHOLO Conference marks the resumption of the OHOLO tradition after 8 years of interruption caused by events beyond our control. It is my belief that our uncomp- mising commitment to excellence in research and development in the various areas of science in Israel is essential to our survival in this troubled region. The OHOLO conference tradition is a re?ection of this conviction. The present 46th OHOLO Conference entitled: The Challenge of Highly Pathogenic Microorganisms ¿ Mechanisms of Virulence and Novel Medical Countermeasures intends to address the unique virulence features and ho- pathogen interactions of microorganisms constituting emerging biothreat with emphasis on Y. pestis, B. anthracis, F. tularensis and Orthopox viruses. Accordingly we selected classical microbiological as well as genomic, proteomic & transcr- tomic approaches towards developments of novel prophylactic and post-exposure treatment, as well as updated strategies of diagnostics and bioforensics.
Sprache: Englisch
Verlag: Springer Verlag, 2011
Serie: Buch 74 von 544 - Advances in Experimental Medicine and Biology
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Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The OHOLO conferences are sponsored by the Israel Institute for Biological Research and take their name from the site of the rst meeting on the shores of Lake Kinnereth. The purpose of these meetings is, as it was at their inception over 50 years ago, 'to f…oster interdisciplinary communication between scientists in Israel, and to provide added stimulus by the participation of invited scientists from abroad'. The core of the organizers of the OHOLO conferences are scientists from the Israel Institute for Biological Research. From time to time a particular OHOLO conference cooperates with an international scienti c organization. The present 46th OHOLO Conference marks the resumption of the OHOLO tradition after 8 years of interruption caused by events beyond our control. It is my belief that our uncomp- mising commitment to excellence in research and development in the various areas of science in Israel is essential to our survival in this troubled region. The OHOLO conference tradition is a re ection of this conviction. The present 46th OHOLO Conference entitled: The Challenge of Highly Pathogenic Microorganisms - Mechanisms of Virulence and Novel Medical Countermeasures intends to address the unique virulence features and ho- pathogen interactions of microorganisms constituting emerging biothreat with emphasis on Y. pestis, B. anthracis, F. tularensis and Orthopox viruses. Accordingly we selected classical microbiological as well as genomic, proteomic & transcr- tomic approaches towards developments of novel prophylactic and post-exposure treatment, as well as updated strategies of diagnostics and bioforensics.
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The OHOLO conferences are sponsored by the Israel Institute for Biological Research and take their name from the site of the rst meeting on the shores of Lake Kinnereth. The purpose of these meetings is, as it was at their inception over 50 years ago…, 'to foster interdisciplinary communication between scientists in Israel, and to provide added stimulus by the participation of invited scientists from abroad'. The core of the organizers of the OHOLO conferences are scientists from the Israel Institute for Biological Research. From time to time a particular OHOLO conference cooperates with an international scienti c organization. The present 46th OHOLO Conference marks the resumption of the OHOLO tradition after 8 years of interruption caused by events beyond our control. It is my belief that our uncomp- mising commitment to excellence in research and development in the various areas of science in Israel is essential to our survival in this troubled region. The OHOLO conference tradition is a re ection of this conviction. The present 46th OHOLO Conference entitled: The Challenge of Highly Pathogenic Microorganisms - Mechanisms of Virulence and Novel Medical Countermeasures intends to address the unique virulence features and ho- pathogen interactions of microorganisms constituting emerging biothreat with emphasis on Y. pestis, B. anthracis, F. tularensis and Orthopox viruses. Accordingly we selected classical microbiological as well as genomic, proteomic & transcr- tomic approaches towards developments of novel prophylactic and post-exposure treatment, as well as updated strategies of diagnostics and bioforensics.
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