aukunuru jithan (1 Ergebnisse)

Hardcover. Zustand: New. 2nd Edition. Contents Foreword. Preface. Part I. New drugs and formulations 1. New drug substances. 2. Evaluation of early development candidates physical properties. 3. Evaluation of early development candidates drug safety. 4. Complimentary techniques for solid state drug analysis. 5. Salt selection characterization and polymorphism assessment. 6. Dissolution testing. 7. Oral formulations. 8. Novel drug delivery systems. 9. Oral drug regulatory departments and guidelines. 10. Pharmaceutical technology. 11. Product processing and evaluation. 12. Quality control investigations. 13. Biotechnology products. Part II. Drug transport and pharmaceutical statistics 14. Gastro intestinal tract membrane drug transport. 15. Oral pharmacokinetics. 16. Biopharmaceutics a clinical trial perspective. 17. Drug absorption study models. 18. Drug absorption improvement techniques. 19. Prodrugs design kinetic study and synthesis. 20. Pharmaceutical statistics in oral drug development. 21. Statistical methodologies in the quality control of the industrial processes an oral drug industry perspective. Index. In recent years oral formulations development has undergone a phenomenal growth both in theory and practice. Especially with the introduction of high throughput synthesis and screening a great number of molecules are reaching the hands of a formulator be it an industrial formulator or a practicing pharmacist. In both cases the first formulations developed are intended to be administrator orally. For efficient oral formulations development a thorough understanding of pharmaceutical technology is needed with a good comprehension of drug transport across the gastro intestinal tract new drug discovery biopharmaceutics pharmacokinetics delivery systems prodrugs and regulatory affairs. Attempts have been made to familiarize the readers with all these and their theoretical and practical aspects. A chapter on drug safety and two chapters on statistics with practical examples have been included. Each chapter is provided with questions intended for the application of the theories and methods taught in that chapter keeping in mind the syllabi for pharmaceutics medicinal chemistry and pharmacology streams. A selective reference of the relevant recent literature on this field comprising mostly of textbooks monographs and review articles is given. This textbook can be adopted at any stage of university teaching. It would also be useful for the industrial personnel. This book would be called a complete guide for every pharmacist who wants to know on oral formulations. 638 pp.