Stanley t. crooke (43 Ergebnisse)

Hardcover. Zustand: Good. No Dust Jacket. hard back is very solid and shows signs of age, including a small tear to top of spine. Pages are clean and tight but pageblock edges are age-tanned.

Zustand: Very Good. 1987th Edition. Pages intact with possible writing/highlighting. Binding strong with minor wear. Dust jackets/supplements may not be included. Stock photo provided. Product includes identifying sticker. Better World Books: Buy Books. Do Good.

Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Zustand: New. In English.

Zustand: New. In English.

Zustand: New. In English.

Paperback. Zustand: Brand New. reprint edition. 218 pages. 9.01x5.98x0.50 inches. In Stock.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - I. Na+, K+, and H+ Transport.- 1 Molecular Properties of Voltage-Sensitive Sodium Channels.- II. Proton Pumps and Electrochemical Gradients.- 2 Studies of a Biological Energy Transducer: The lac Permease of Escherichia coli.- 3 The Erythrocyre Anion-Exchange Protein: Primary Structure Deduced from the cDNA Sequence and a Model for Its Arrangement within the Plasma Membrane.- 4 The Lysosomal Proton Pump.- 5 Ion PumpSy Ion Pathways, Ion Sites.- III. Calcium Channels and the Calcium Pump.- 6 Shifts between Modes of Calcium Channel Gating as a Basis for Pharmacologic Modulation of Calcium Influx in Cardiac, Neuronal, and Smooth-Muscle-Derived Cells.- 7 Chemical Pharmacology of Ca2+ Channel Ligands.- 8 Information Flow in the Calcium Messenger System.- 9 Neutrophil Activation, Polyphosphoinositide Hydrolysis, and the Guanine Nucleotide Regulatory Proteins.- IV. Inositol Lipids and the Calcium-Mediated Cellular Responses.- 10 Agonist-Dependent Phosphoinositide Metabolism: A Bifurcating Signal Pathway.- 11 Hormone-Induced Inositol Lipid Breakdown and Calcium-Mediated Cellular Responses in Liver.- 12 Comparison of the Na+ Pump and the Ouabain-Resistant K+ Transport System with Other Metal Ion Transport ATPases.- 13 Current Concepts of Tumor Promotion by Phorbol Esters and Related Compounds.- V. Cell Polarity and Membrane Transport Processes.- 14 Intracellular Protein Topogenesis.- 15 Analysis of Epithelial Cell Surface Polarity Development with Monoclonal Antibodies.- 16 Frequency and Time Domain Analysis of Epithelial Transport Regulation.- 17 The Epithelial Sodium Channel.- VI. Endocytosis as a Cell Transport Pathway.- 18 Uptake and Intracellular Processing of Cell Surface Receptors: Current Concepts and Prospects.- 19 Sorting in the Prelysosomal Compartment (CURL): Immunoelectron Microscopy of Receptors and Ligands.- 20 Mechanisms of Molecular Sorting in Endosomes.- 21 Transport of Protein Toxins across Cell Membranes.…

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The heat-shock proteins in E. coli are transiently overexpressed af ter shift to a higher growth temperature. The genes that encode the HSPs are preceded by promoters transcribed in vitro by a form of RNA poly 32 32 merase holoenzyme containing a 32-kd a subunit (Ea ). The a subunit is encoded by the rpoH (htpR) gene, previously identified as a positive 32 effector of the heat-shock response. Our evidence suggests that Ea is the enzyme that transcribes heat-shock genes at all temperatures. The level 32 of a may be regulated at several points: Accumulation of rpoH mRNA 32 is affected by temperature shift, a synthesis is regulated posttranscrip 32 tionally, and a is an unstable molecule with a tl/2 of 5 min. Many mu tations in the HSPs are shown to have defects in proteolysis. References Baker. T. A. , Grossman. A. D . . and Gross. C. A. , 1984, A gene regulating the heat shock response in Escherichia coli also affects proteolysis. Proc. Natl. A cad. Sci. US. A. 81:6779-6783. Bardwell, J. C. A . . and Craig, E. A . . 1984. Major heat shock gene of Drosophila and the Escherichia coli heat-inducible dnaK gene are homologous, Proc. Natl. Acad. Sci. US. A. 81:848-852. Bukhari. A. I. . and Zipser. D . . 1973, Mutants of Escherichia coli with a defect in the degradation of nonsense fragments, Nature New Bioi. 243:238-241. Charette. M. F. , Henderson, G. W. , and Markovitz, A.…

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - It is less than 80 years since John Newport Langley first proposed the role of 'receptive substances' as the site of drug action from his obser vations on the effects of nicotine and curare at the myoneural junction. The many advances in our understanding of receptor biology that have occurred during the intervening period mirror the extraordinary growth of knowledge in the biological sciences and in cell and molecular biology in particular. Receptor biology, in common with many other topics in contemporary biology, is on the threshold of a transition from being a descriptive, phenomenological discipline to one in which underlying mechanisms and regulatory principles can be defined with increasing pre cision. This change, together with the evolution of powerful analytical techniques and timely convergence of ideas from a number of previously separate fields of inquiry, is generating an increasingly unified theoretical and experimental framework for the study of receptor function. These themes, and the mood of anticipation that a real understanding of receptor function in health and disease is emerging, are reflected in in this volume, which summarizes the proceedings of the Sec the papers ond Smith Kline & French Research Symposium on New Horizons in Therapeutics held in Philadelphia in 1984.…

Paperback. Zustand: Brand New. reprint edition. 478 pages. 9.02x5.98x1.04 inches. In Stock.

Paperback. Zustand: Brand New. 484 pages. 9.02x5.98x1.05 inches. In Stock.

Zustand: Used. pp. 496.

Zustand: New.

Zustand: New.

Zustand: Used. pp. 496.

Paperback. Zustand: Brand New. 312 pages. 9.25x6.00x0.71 inches. In Stock.

Paperback. Zustand: Brand New. 414 pages. 9.25x6.00x0.94 inches. In Stock.

Zustand: Fair. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. In fair condition, suitable as a study copy. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,800grams, ISBN:0306416549. …

Zustand: New. In English.

Zustand: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher | Keine Beschreibung verfügbar.

Zustand: Good. Former library copy. Pages intact with minimal writing/highlighting. The binding may be loose and creased. Dust jackets/supplements are not included. Includes library markings. Stock photo provided. Product includes identifying sticker. Better World Books: Buy Books. Do Good.

Zustand: New. In English.

Paperback. Zustand: Brand New. reprint edition. 522 pages. 9.02x5.98x1.13 inches. In Stock.

Zustand: New.

Taschenbuch. Zustand: Neu. Neuware - The characterization of the cellular and molecular mechanisms that mediate inflammation provides a foundation that supports future studies that will de fine mechanisms more intimately. It encourages substantial optimism about the opportunities to understand the inflammatory process and to use that information to develop novel therapeutic approaches. Recent progress has defined the cells that mediate the inflammatory response, many of the inter cellular transmitters, the receptors, signal transduction processes and regula tory mechanisms. Thus, we now have the opportunity to understand inflammation in pharmacologic terms and to attack the key molecular targets to develop new therapeutics. Among the cells involved in the inflammatory response are the lympho cytes, neutrophils and endothelial cells. Maintenance of homeostasis, re sponse to proinflammatory stimuli and pathophysiologic responses are products of complex interactions between these and other elements of the immune systems. Each of these cells displays a variety of receptors to define the stimuli to which they respond. The receptors displayed that the signal transduction processes and cellular responses are regulated genetically and epigenetic ally . The critical role of membranes and particularly the phospho lipid components of the membranes is emphasized by recent studies.…

Zustand: Sehr gut. Zustand: Sehr gut | Seiten: 660 | Sprache: Englisch | Produktart: Bücher | Antisense technology may result in dramatic changes in the therapy of many diseases and may provide tools to dissect pharmacological processes and to confirm the roles of various genes. In this volume, progress in the understanding of antisense technology and its use in creating new drugs is discussed. Potential caveats, pitfalls and limitations of the technology are also presented. In the next few years the pace at which new molecular targets will be identified will increase exponentially as the sequencing of the human genome and of other genomes proceeds. …

Hardcover. Zustand: gut. 1998. Antisense Research and Application (Handbook of Experimental Pharmacology. Continuation of Handbuch der experimentellen Pharmakologie, Vol. 131) In deutscher Sprache. pages.

Zustand: Good. Your purchase helps support Sri Lankan Children's Charity 'The Rainbow Centre'. Ex-library, so some stamps and wear, but in good overall condition. Our donations to The Rainbow Centre have helped provide an education and a safe haven to hundreds of children who live in appalling conditions.…

Zustand: New. Stanley T. CrookeExtensively revised and updated, Antisense Drug Technology: Principles, Strategies, and Applications, Second Edition reflects the logarithmic progress made in the past four years of oligonucleotide-based therapies, and, in.