This thesis presents a scalable, generic methodology for microbial phenotype prediction based on supervised machine learning, several models for biological and ecological traits of high relevance, and the deployment in metagenomic datasets. The results suggest that the presented prediction tool can be used to automatically annotate phenotypes in near-complete microbial genome sequences, as generated in large numbers in current metagenomic studies. Unraveling relationships between a living organism's genetic information and its observable traits is a central biological problem. Phenotype prediction facilitated by machine learning techniques will be a major step forward to creating biological knowledge from big data.
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Roman Feldbauer is currently employed at the Austrian Research Institute for Artificial Intelligence (OFAI) and PhD student at the University of Vienna. His research interests are machine learning, data science, bioinformatics, comparative genomics and neuroscience. In one of his current projects he investigates large biological databases in regard to the „curse of dimensionality“.
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This thesis presents a scalable, generic methodology for microbial phenotype prediction based on supervised machine learning, several models for biological and ecological traits of high relevance, and the deployment in metagenomic datasets. The results suggest that the presented prediction tool can be used to automatically annotate phenotypes in near-complete microbial genome sequences, as generated in large numbers in current metagenomic studies. Unraveling relationships between a living organism's genetic information and its observable traits is a central biological problem. Phenotype prediction facilitated by machine learning techniques will be a major step forward to creating biological knowledge from big data. Artikel-Nr. 9783658143183
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Taschenbuch. Zustand: Neu. Machine Learning for Microbial Phenotype Prediction | Roman Feldbauer | Taschenbuch | BestMasters | xiii | Englisch | 2016 | Springer | EAN 9783658143183 | Verantwortliche Person für die EU: Springer Spektrum in Springer Science + Business Media, Tiergartenstr. 15-17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. Artikel-Nr. 103802188
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