The Textbook of Contact Dermatitis covers every conceivable aspect of modern day management of contact dermatitis. Both irritatnt and allergic types of contact dermatitis are dealt with clearly and comprehensively, special emphasis being given to occupational aspects as well as to prevention, diagnosis and treatment. Also covered are epidemiological aspects, computerization of patch test data and patient imformation systems, noninvasive bioengineering measurement techniques, methods of skin testing other than patch testing, histopathology of both irritant and allergic contact dermatitis, and subjective reactions. The editors and contributing authors are all leading practitioners in the field. Their expertise has been brought to bear to
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10. 1. 1. 1 The Purpose of Patch Testing Patch testing is a well-established method of diagnosing allergic contact dermatitis, a delayed type of hypersensitivity (type IV reaction). Patients with a history and clinical picture of contact dermatitis are reexposed to the suspected allergens under controlled conditions to verify the diagnosis. Besides testing patients with hand, arm, face or leg eczema (stasis dermatitis), testing of other types of eczema (atopic, seborrhoeic dermatitis, nummular eczema) is sometimes indicated, especially when the dermatologist suspects contact allergy to prescribed topical medicaments and their vehicles. Apart from its use to confirm a suspected allergic contact dermatitis, the patch test procedure can also be used before recommending alternative corti costeroids, skin care products, cosmetics, gloves, etc. in a particular patient. If the patient does not react to the alternatives tested, it is very unlikely that she or he will react to the products in ordinary use. 10. 1. 1.2 Standardization The first patch tests according to present principles were carried out in 1895 [1], but were preceded by some preliminary experiments [2] (see Chap. 1).
The Textbook of Contact Dermatitis covers every conceivable aspect of modern day management of contact dermatitis. Both irritatnt and allergic types of contact dermatitis are dealt with clearly and comprehensively, special emphasis being given to occupational aspects as well as to prevention, diagnosis and treatment. Also covered are epidemiological aspects, computerization of patch test data and patient imformation systems, noninvasive bioengineering measurement techniques, methods of skin testing other than patch testing, histopathology of both irritant and allergic contact dermatitis, and subjective reactions. The editors and contributing authors are all leading practitioners in the field. Their expertise has been brought to bear to
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