Protein Homology Detection Through Alignment of Markov Random Fields: Using MRFalign (SpringerBriefs in Computer Science) - Softcover

Buch 170 von 322: SpringerBriefs in Computer Science

Xu, Jinbo

 
9783319149134: Protein Homology Detection Through Alignment of Markov Random Fields: Using MRFalign (SpringerBriefs in Computer Science)
Softcover
ISBN 10: 331914913X ISBN 13: 9783319149134
Verlag: Springer, 2015

Inhaltsangabe

This work covers sequence-based protein homology detection, a fundamental and challenging bioinformatics problem with a variety of real-world applications. The text first surveys a few popular homology detection methods, such as Position-Specific Scoring Matrix (PSSM) and Hidden Markov Model (HMM) based methods, and then describes a novel Markov Random Fields (MRF) based method developed by the authors. MRF-based methods are much more sensitive than HMM- and PSSM-based methods for remote homolog detection and fold recognition, as MRFs can model long-range residue-residue interaction. The text also describes the installation, usage and result interpretation of programs implementing the MRF-based method.

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Von der hinteren Coverseite

This work covers sequence-based protein homology detection, a fundamental and challenging bioinformatics problem with a variety of real-world applications. The text first surveys a few popular homology detection methods, such as Position-Specific Scoring Matrix (PSSM) and Hidden Markov Model (HMM) based methods, and then describes a novel Markov Random Fields (MRF) based method developed by the authors. MRF-based methods are much more sensitive than HMM- and PSSM-based methods for remote homolog detection and fold recognition, as MRFs can model long-range residue-residue interaction. The text also describes the installation, usage and result interpretation of programs implementing the MRF-based method.

„Über diesen Titel“ kann sich auf eine andere Ausgabe dieses Titels beziehen.

Verlag
Springer
Erscheinungsdatum
2015
Sprache
Englisch
ISBN 10 
331914913X
ISBN 13 
9783319149134
Einband
Taschenbuch
Anzahl der Seiten
60
Kontakt zum Hersteller
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Darmstadt
64293
Deutschland

Weitere beliebte Ausgaben desselben Titels

9783319149158: Protein Homology Detection Through Alignment of Markov Random Fields: Using MRFalign

Vorgestellte Ausgabe

ISBN 10:  3319149156 ISBN 13:  9783319149158
Verlag: Springer, 2015
Softcover