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Inhaltsangabe
This new edition reflects the progression of gapmer research from conceptual foundations to experimental implementation and analytical detection. Beginning with a section covering historical perspectives and the clinical context of antisense gapmers, the book continues with molecular design principles, experimental strategies for developing effective antisense oligonucleotides, methods to evaluate their efficacy and selectivity in cellular and animal models, and analytical approaches for detecting and quantifying antisense oligonucleotides in biological samples. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detailed implementation advice needed to ensure success in the lab.
Authoritative and up-to-date, Gapmers: Methods and Protocols, Second Edition serves as a valuable resource for researchers and clinicians aiming to accelerate the development of next-generation antisense therapeutics.
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This new edition reflects the progression of gapmer research from conceptual foundations to experimental implementation and analytical detection. Beginning with a section covering historical perspectives and the clinical context of antisense gapmers, the book continues with molecular design principles, experimental strategies for developing effective antisense oligonucleotides, methods to evaluate their efficacy and selectivity in cellular and animal models, and analytical approaches for detecting and quantifying antisense oligonucleotides in biological samples. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detailed implementation advice needed to ensure success in the lab.
Authoritative and up-to-date, Gapmers: Methods and Protocols, Second Edition serves as a valuable resource for researchers and clinicians aiming to accelerate the development of next-generation antisense therapeutics.
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Gapmers : Methods and Protocols
Verlag:
Springer-Verlag New York Inc., 2026
ISBN 10: 1071654756
ISBN 13: 9781071654750
Neu
Hardcover
Anbieter: AHA-BUCH GmbH, Einbeck, Deutschland
Verkäuferbewertung 5 von 5 Sternen
Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This new edition reflects the progression of gapmer research from conceptual foundations to experimental implementation and analytical detection. Beginning with a section covering historical perspectives and the clinical context of antisense gapmers, the book continues with molecular design principles, experimental strategies for developing effective antisense oligonucleotides, methods to evaluate their efficacy and selectivity in cellular and animal models, and analytical approaches for detecting and quantifying antisense oligonucleotides in biological samples. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detailed implementation advice needed to ensure success in the lab.Authoritative and up-to-date, Gapmers: Methods and Protocols, Second Edition serves as a valuable resource for researchers and clinicians aiming to accelerate the development of next-generation antisense therapeutics. Artikel-Nr. 9781071654750
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