Translational Controls in Biology and Medicine

The editors are to be congratulated on assembling an outstanding collection of contributions and contributors. While which chapters you choose to read will undoubtedly reflect your specific interests, I would encourage all to read the opening chapter written by the editors where they provide a highly readable review of the origins, mechanisms and targets of translational control and in so doing provide an important historical context for readers new to this hot topic. Even if you already have the previous edition of Translational Control (as I do), then that should not inhibit you from buying this new edition; it is not just an updated version of the previous editions. The editors have introduced a significant number of new topics, some of which (for example, microRNAs) were not yet on the radar in 2000. Where topics have been covered in the previous edition(s), they have succeeded in their stated aim of getting chapters that are stimulating, edifying and authoritative and in several cases have used different authors to ring the changes . --Genetical Research

Sequels often suffer from several shortcomings, including the monotonous repetition of ideas and the absence of the most recent advances. Readers of previous versions might have expected only a modestly updated and expanded version this time. But they are in for a surprise: all of the chapters are either substantially rewritten or are completely new and contributed by new authors. This guarantees that the book is up to date and offers fresh ideas on the future of translation research. Given the scope of this book, even the editors themselves warn that few will choose to read this volume from cover to cover, and certainly not in sequence. I did, and I am glad. This book should not be missing from the shelves of any scholars of translation. --Nature Cell Biology

The new edition has been both updated and broadened. Since the previous (second) edition was published in 2000, the structures of the bacterial and eukaryotic ribosomes have been published, advancing our basic understanding of translation and mechanisms involving protein and RNA regulators. In addition, as the title indicates, this edition has a new focus on the role of translational control in human development and disease. Each reader will find out his own loved chapterbut all 30 chapters are an essential reading for anyone interested in the process of translation, its regulation, and how its failure can be the cause of disease. --European Journal of Histochemistry