springer us springer us mai 2016 (5 Ergebnisse)

Buch. Zustand: Neu. Neuware -The editors of this volume have compiled an important book that is a useful vehicle for important computational research - in the development of theoretical methodologies and their practical applications. Themes include new methodologies, state-of-the-art computational algorithms and hardware as well as new applications. This volume, Practical Aspects of Computational Chemistry IV, is part of a continuous effort by the editors to document recent progress made by eminent researchers. Most of these chapters have been collected from invited speakers from the annual international meeting: ¿Current Trends in Computational Chemistry¿ organized by Jerzy Leszczynski, one of the editors of the current volume. This conference series has become an exciting platform for eminent Theoretical/Computational Chemists to discuss their recent findings and is regularly honored by the presence of Nobel laureates. Certainly, it is not possible to cover all topics related to the Computational Chemistry in asingle volume but we hope that the recent contributions in the latest volume of this collection adequately highlight this important scientific area.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 408 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -The cognitive and behavioral implications of sleep deprivation have been noted in the medical literature for many years. In addition, emerging research continues to demonstrate the contribution of sleep deprivation to some of the most common and costly health conditions today.Sleep Deprivation and Disease provides clinically relevant scientific information to help clinicians, public health professionals, and researchers recognize the ramifications of sleep deprivation across a broad spectrum of health topics. This timely reference covers sleep physiology, experimental approaches to sleep deprivation and measurement of its consequences, as well as health and operational consequences of sleep deprivation. Clinical challenges and areas of uncertainty are also presented in order to encourage future advancements in sleep medicine and help patients avoid the outcomes associated with the myriad causes of sleep deprivation.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 304 pp. Englisch.

Buch. Zustand: Neu. Neuware -This book grew out of the need to provide students with a solid introduction to modern fluid dynamics. It offers a broad grounding in the underlying principles and techniques used, with some emphasis on applications in astrophysics and planetary science.The book comprehensively covers recent developments, methods and techniques, including, for example, new ideas on transitions to turbulence (via transiently growing stable linear modes), new approaches to turbulence (which remains the enigma of fluid dynamics), and the use of asymptotic approximation methods, which can give analytical or semi-analytical results and complement fully numerical treatments. The authors also briefly discuss some important considerations to be taken into account when developing a numerical code for computer simulation of fluid flows.Although the text is populated throughout with examples and problems from the field of astrophysics and planetary science, the text is eminently suitable as a general introduction to fluid dynamics. It is assumed that the readers are mathematically equipped with a reasonable knowledge in analysis, including basics of ordinary and partial differential equations and a good command of vector calculus and linear algebra.Each chapter concludes with bibliographical notes in which the authors briefly discuss the chapter's essential literature and give recommendations for further, deeper reading. Included in each chapter are a number of problems, some of them relevant to astrophysics and planetary science. The book is written for advanced undergraduate and graduate students, but will also prove a valuable source of reference for established researchers.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 704 pp. Englisch.

Buch. Zustand: Neu. Neuware -Many breakthroughs in biological research and translational healthcare advancements have been achieved by studying the response of biological systems to extreme environments. The spaceflight platform provides a unique environment where researchers can explore fundamental questions into cellular and molecular response mechanisms to unveil novel insight into human health and disease. Since the physical force of gravity has shaped the architecture of all biological systems on our planet, spaceflight provides the opportunity to see life in a new adaptational mode - in response to reduced gravity. This enables investigations into the effects of the microgravity environment and associated changes in mechanical forces on mammalian cells/tissues and microbial pathogens, to bring novel insight into disease mechanisms, which are not discernable using conventional experimental approaches.Research using spaceflight platforms represents a paradigm shift in how we observe life processes and is on the leading edge of research discoveries into cellular and molecular mechanisms of health and disease. By incorporating the views of leading authors,this book highlights landmark discoveries and advances in mammalian cellular and microbiology research in both true spaceflight and ground-based spaceflight analogue environments for scientists and students alike who are interested in the influence of physical forces on mammalian and microbial cells, how this impactstransitionbetween normal homeostasis and disease, and basic mechanisms of adaptation to low gravity environments.To provide a thorough understanding of this research, this book covers a range of topics including:(i)description the physical forces interacting with cells in microgravity and microgravity analogue environments(ii)how alterations in these cellular forces impact human physiology, specifically immune function(iii)useof these environments to develop organotypic three-dimensional (3-D) tissue culture models as predictive human surrogates for organogenesis and disease research, and(iv)microbial pathogen responses to culture in these environments, focusing on infectious diseaseCollectively, this information reflects a critical step in preparation for long-duration human space exploration, advances our knowledge of basic biological processes and mechanisms important to understand normal function and disease, and may lead to new strategies for treatment and prevention.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 320 pp. Englisch.

Buch. Zustand: Neu. Neuware -This volume aims to outline the current status of the Mesenchymal Stem Cells(MSC) field in regenerative medicine and to propose clear and reproducible protocols to better define the identity, function and use of these cells that are today, more than ever, ¿under the spotlight¿. Mesenchymal Stem Cells: Methods and Protocols, Second Edition is organized into four sections. The first guides the reader through a series of state-of-the-art reviews summarizing the use of MSC for the treatment of various diseases. The other three sections are a collection of methodological chapters covering several aspects: isolation and characterization of MSC; expansion of MSC for clinical use; production and characterization of the MSC secretome. Written in the highly successful Methods in Molecular Biology series format, the method chapters include introductions to their respective topics, complete lists of the necessary materials and reagents, step-by-step, readily reproduciblelaboratory protocols, and tips on troubleshooting which will help the researcher to avoid known pitfalls.Authoritative and cutting-edge, Mesenchymal Stem Cells: Methods and Protocols, Second Edition, aims to ensure successful results in the further study of this vital field.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 592 pp. Englisch.