springer us springer us dez 2015 (21 Ergebnisse)

Buch. Zustand: Neu. Neuware -The Internet and related technologies havedramatically changed the way we live, work, socialize, and even topple nationalgovernments. As the Internet becomes increasingly pervasive across societieswe find more often that governments adopt Information CommunicationTechnologies (ICTs) as part of their toolbox for facilitating efficient andcitizen-oriented service delivery at all levels of government. Local governmentsacross the major industrialized democracies have not been an exception to thistrend and have set sail into the age of digital government. Closest to theircitizens, towns and cities have adopted ICTs to facilitate electronicgovernment (e-government). While research on local e-government functionalityin terms of information dissemination, service delivery, and citizen engagementcontinues at an impressive empirical and methodological pace, gaps in ourknowledge remain. Cross-national comparative research on local e-governmentthat covers a wide range of municipalities in combination with in-depth casestudy analyses is lacking. Informed by a comparative case study approach, thisbook seeks to narrow that gap and offer practical policy solutions tofacilitate local e-government. We do so by pursuing both a macro and microperspective of e-government functionality in the federal republics of Germanyand the United States and unitary France and Japan. The macro perspectivefocuses on the state and scope of e-government functionalityacross a large number of randomly selected municipalities of all sizes in theseadvanced industrialized countries. Based on a small sample of case studies, themicro perspective analyzes the successful implementation of e-government inSeattle (United States), Nuremberg (Germany), Bordeaux (France), and Shizuoka City(Japan).Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 136 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -With hundreds of question and answer items and bite-sized chunks of information that can be read and processed easily, reviewing for the pediatric board exams - or just brushing up in your spare time - has never been easier. Pediatric Tricky Topics, Volume 2: A Practically Painless Review includes review items in pediatric immunology, hematology, oncology, nephrology, urology, dermatology, ophthalmology, otorhinolaryngology, and gynecology, among others. Selected expanded sections provide more in-depth information, while the Q&A format allows for self-testing or study with a partner or a group and is practical and accessible enough to dip into during a few minutes of downtime at the hospital or office. As such, it is suitable for those studying for the pediatric board exam, practicing physicians brushing up their skills, and any busy medical student, nurse or clinician who wants to learn more about these topics while on the go.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 368 pp. Englisch.

Buch. Zustand: Neu. Neuware -This volume aims to present a large panel of techniques for the study of Plant Cell Division. Plant Cell Division: Methods and Protocols captures basic experimental protocols that are commonly used to study plant cell division processes, as well as more innovative procedures. Chapters are split into five parts covering several different aspect of plant cell division such as, cell cultures for cell division studies, cell cycle progression and mitosis, imaging plant cell division, cell division and morphogenesis, and cytokinesis. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, Plant Cell Division: Methods and Protocols is a valuable tool for the study of plant cell division at both the cellular and molecular levels, and in the context of plant development.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 260 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -This book discusses three levels of e-government and national strategies to reach a citizen-centric participatory e-government, and examines how disruptive technologies help shape the future of e-government.The authors examine how e-government can facilitate a symbiotic relationship between the government and its citizens. ICTs aid this relationship and promote transparencies so that citizens can place greater trust in the activities of their government. If a government can manage resources more effectively by better understanding the needs of its citizens, it can create a sustainable environment for citizens. Having a national strategy on ICT in government and e-government can significantly reduce government waste, corruption, and inefficiency.Businesses, CIOs and CTOs in the public sector interested in meeting sustainability requirements will find this book useful.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 124 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -This practical handbook offers quick and sound advice on the many issues faced when dialyzing the older patient. It is authored by well-known international experts who have covered the full range of end stage renal disorders including treatment options, patient management and maximization of quality of life. Accessible and easy-to-read, Dialysis in Older Adults serves as the go-to reference for clinicians and members of their team as they treat this challenging patient population.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 232 pp. Englisch.

Buch. Zustand: Neu. Neuware -This book provides readers with the fundamental, analytical, and quantitative knowledge of machining process planning and optimization based on advanced and practical understanding of machinery, mechanics, accuracy, dynamics, monitoring techniques, and control strategies that they need to understanding machining and machine tools. It is written for first-year graduate students in mechanical engineering, and is also appropriate for use as a reference book by practicing engineers. It covers topics such as single and multiple point cutting processes; grinding processes; machine tool components, accuracy, and metrology; shear stress in cutting, cutting temperature and thermal analysis, and machine tool chatter. The second section of the book is devoted to ¿Non-Traditional Machining,¿ where readers can find chapters on electrical discharge machining, electrochemical machining, laser and electron beam machining, and biomedical machining. Examples of realistic problems that engineers are likely to face in the field are included, along with solutions and explanations that foster a didactic learning experience.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 248 pp. Englisch.

Buch. Zustand: Neu. Neuware -This third edition volume expands upon the previous editions with new research topics and numerous leading-edge HIV protocols. This book contains chapters that cover various aspects of HIV-1 replication and are helpful for investigating the mechanisms of HIV-1 replication or pathogenesis. The chapters are grouped into six sections: HIV early events; HIV-1 RNA structure and RNA-protein interactions; HIV-1 post-integration events; HIV-1 pathogenesis in animal models; tools to study HIV-1 latency; and Neuro AIDS. Chapters are written by research experts who have diligently developed techniques, improved them, simplified them, or applied them to their own HIV research. Written in the highly successful Methods in Molecular Biology series format, the chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, HIV Protocols, Third Edition is a great resource for HIV research, and contains many significant tips and tricks rarely mentioned in standard protocols.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 404 pp. Englisch.

Buch. Zustand: Neu. Neuware -This book compiles andexplores cutting-edge research in degenerative skeletal disorders, such asDuchenne muscular dystrophy and congenital myopathy, and new stem-cell basedtherapies and gene replacement therapy. Twelve expertly-authored chapters navigatethe nuances of these treatments in an array of contexts and biological systems.The topics covered include: How are urine cells from a patient with Duchennemuscular dystrophy transformed into beating heart cells What can reprogrammedcells tell us about heart muscle failure What do gene mutations mean for thoseborn with a muscle disease How are manufacturing methods applied to human stemcells Does therapeutic exercise benefit those patients who receive engineeredlimb muscle Is there practical advice about nutrition to enhance musclefunction for the Duchenne patient Can microRNAs be useful to regeneratediseased muscle RegenerativeMedicine for Degenerative Muscle Diseases is ideal for scientistsand clinicians from varying disciplines in genetics, cell biology, virologycell-based manufacturing, rehabilitation medicine, nutrition, veterinarymedicine and neurosurgery. The reader will see how transformative changes occurin medicine that can powerfully impact the future for patients suffering frominherited disorders affecting muscles of the body, including the heart.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 352 pp. Englisch.

Buch. Zustand: Neu. Neuware -This volume provides a practical, comprehensive overview on benign and malignant disease of the adult kidney. The text addresses the topic of assessment and management of patients with surgical renal disease. Within this scope,it includes hereditary and spontaneous renal neoplasms, as well as non-neoplastic diseasethat manifests as a clinically relevant mass.The book is organized into chapters focusing on discrete disease entities and incorporating pathology, surgical management, oncologic therapy, radiologic findings,and molecular alterations. This text is designed to address relevant areas of clinical management of renal neoplastic and non-neoplastic disease across multiple specialties and levels of training.Written by experts in the field, The Kidney: A Comprehensive Guide to Pathologic Diagnosis and Management is a valuable resource on the diagnosis and management of patients with not only renal cell carcinoma, but also other renal processes that require surgical intervention.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 228 pp. Englisch.

Buch. Zustand: Neu. Neuware -This book covers the latest research work done in the area of interface mechanics of collagen and chitin-based biomaterials along with various techniques that can be used to understand mechanics of biological systems and materials. Topics covered include Raman spectroscopy of biological systems, scale dependence of the mechanical properties and microstructure of crustaceans thin films as biomimetic materials, as well as the role of molecular-level modeling. The use of nanomechanics to investigate interface thermomechanics of collagen and chitin-based biomaterials is also covered in detail.This book also:¿ Details spectroscope experiments as well as nanomechanic experiments¿ Reviews exhaustively phenomenological models and Raman spectroscopy of biological systems¿ Covers the latest in multiscaling for molecular models to predict lab-scale sample properties and investigates interface thermomechanicsSpringer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 104 pp. Englisch.

Buch. Zustand: Neu. Neuware -This volume provides an understanding of the factors involved in nuclear reprogramming, which is essential for the success of reprogramming. The book is aimed at reprogramming differentiated cells and germ line transmission of pluripotent stem cells and features chapters that deal with reprogramming-related issues such as analysis of mitochondrial DNA in reprogrammed cells and the isolation of reprogramming intermediates; alternative methods for nuclear transfer; the production of germ-line chimeras from embryonic stem cells and induced pluripotent stem cells; and neonatal care and management of somatic cell nuclear transfer derived offspring.Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge,Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 284 pp. Englisch.

Buch. Zustand: Neu. Neuware -Recent efforts to engage more explicitly with the interpretation of emotions in archaeology have sought new approaches and terminology to encourage archaeologists to take emotions seriously. This is part of a growing awareness of the importance of senses¿what we see, smell, hear, and feel¿in the constitution and reconstitution of past social and cultural lives.Yet research on emotion in archaeology remains limited, despite the fact that such states underpin many studies of socio-cultural transformation. The Archaeology of Anxiety draws together papers that examine the local complexities of anxiety as well as the variable stimuli¿class or factional struggle, warfare, community construction and maintenance, personal turmoil, and responsibilities to (and relationships with) the dead¿that may generate emotional responses of fear, anxiousness, worry, and concern.The goal of this timely volume is to present fresh research that addresses the material dimension of rites and performances related to the mitigation and negotiation of anxiety as well as the role of material culture and landscapes in constituting and even creating periods or episodes of anxiety.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 228 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -This comprehensive book covers the knowledge needed to diagnosis and treat patients with acute and chronic pain. Sections dedicated to patient evaluation, medication management, treating patients with more complex circumstances and interventional management provide clinically-relevant information on an array of topics relevant to both the generalist and specialist. Some sections being organized in a diagnosis based approach help to focus on these topics and serve as a quick reference. A practical and easy-to-use guide, Pain Management and Palliative Care provides a broad foundation on pain assessment and management and is an invaluable daily companion for those managing patients experiencing pain.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 412 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -This book provides an overview of the practical aspects of diffusion tensor imaging (DTI), from understanding the basis of the technique through selection of the right protocols, trouble-shooting data quality, and analyzing DTI data optimally. DTI is a non-invasive magnetic resonance imaging (MRI) technique for visualizing and quantifying tissue microstructure based on diffusion. The book discusses the theoretical background underlying DTI and advanced techniques based on higher-order models and multi-shell diffusion imaging. It covers the practical implementation of DTI; derivation of information from DTI data; and a range of clinical applications, including neurosurgical planning and the assessment of brain tumors. Its practical utility is enhanced by decision schemes and a fully annotated DTI brain atlas, including color fractional anisotropy maps and 3D tractography reconstructions of major white matter fiber bundles. Featuring contributions from leading specialists in the field ofDTI, Diffusion Tensor Imaging: A Practical Handbook is a valuable resource for radiologists, neuroradiologists, MRI technicians and clinicians.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 460 pp. Englisch.

Buch. Zustand: Neu. Neuware -Neuromechanics is a new, quickly growing field of neuroscience research that merges neurophysiology, biomechanics and motor control and aims at understanding living systems and their elements through interactions between their neural and mechanical dynamic properties. Although research in Neuromechanics is not limited by computational approaches, neuromechanical modeling is a powerful tool that allows for integration of massive knowledge gained in the past several decades in organization of motion related brain and spinal cord activity, various body sensors and reflex pathways, muscle mechanical and physiological properties and detailed quantitative morphology of musculoskeletal systems. Recent work in neuromechanical modeling has demonstrated advantages of such an integrative approach and led to discoveries of new emergent properties of neuromechanical systems. Neuromechanical Modeling of Posture and Locomotion will cover a wide range of topics from theoretical studies linking the organization of reflex pathways and central pattern generating circuits with morphology and mechanics of the musculoskeletal system (Burkholder; Nichols; Shevtsova et al.) to detailed neuromechanical models of postural and locomotor control (Bunderson; Edwards, Marking et al., Ting). Furthermore, uniquely diverse modeling approaches will be presented in the book including a theoretical dynamic analysis of locomotor phase transitions (Spardy and Rubin), a hybrid computational modeling that allows for in vivo interactions between parts of a living organism and a computer model (Edwards et al.), a physical neuromechanical model of the human locomotor system (Lewis), and others.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 380 pp. Englisch.

Buch. Zustand: Neu. Neuware -This extensive volume explores areas of intense activity related to the very early commitment of stem cells to particular lineages and the progression of differentiation to mature cell stages. Research on embryonic stem cells continues to move very quickly, thus the kinds of studies continue to expand and diversify, and methodologies are continuously being refined and improved, which this book reflects. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions on their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Comprehensive and fully updated, Embryonic Stem Cell Protocols, Third Edition serves as an ideal reference for researchers investigating this rich area of study.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 468 pp. Englisch.

Buch. Zustand: Neu. Neuware -This volume presents an overview of recent advances, innovative applications, and future prospects of in vitro embryogenesis in higher plants. The book's chapters are divided into five parts: Part I contains reviews on general topics (microspore; zygotic and somatic embryogenesis; in vitro and in vivo asexual embryogenesis; advances on the genetic, physiological, and proteomic knowledge of somatic embryo formation; role of apoptosis and mitochondria in somatic embryogenesis; and innovation in the use of bioreactors). The remaining four parts discuss step-wise protocols on somatic embryogenesis in selected horticultural plants (Part II); forest trees (Part III); gametic embryogenesis (Part IV); and pivotal topics, such as the detection of epigenetics modifications during microspore embryogenesis, the in vitro embryogenesis and plant regenerations from isolated zygotes, the synthetics seed production, the induction and maturation of somatic embryos, and the cryostorage of embryogenic cultures (Part V). Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and thorough, In Vitro Embryogenesis in Higher Plants,is a useful source of information and ideas for plant tissue culturists, cell biologists, embryologists, horticulturists, and operators of commercial nurseries. This book will introduce the fascinating work in in vitro embryogenesis in higher plants to students and young scientists.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 576 pp. Englisch.

Buch. Zustand: Neu. Neuware -This book sheds new light on the physiology, molecular biology and pathophysiology of epithelial ion channels and transporters. It combines the basic cellular models and functions by means of a compelling clinical perspective, addressing aspects from the laboratory bench to the bedside. The individual chapters, written by leading scientists and clinicians, explore specific ion channels and transporters located in the epithelial tissues of the kidney, intestine, pancreas and respiratory tract, all of which play a crucial part in maintaining homeostasis. Further topics include the fundamentals of epithelial transport; mathematical modeling of ion transport; cell volume regulation; membrane protein folding and trafficking; transepithelial transport functions; and lastly, a discussion of transport proteins as potential pharmacological targets with a focus on the pharmacology of potassium channels.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 1036 pp. Englisch.

Buch. Zustand: Neu. Neuware -This expert reference provides a broad, comprehensive review of the major domains of sexual offending. Beginning with an integrated etiological model of sexual offending, chapters follow addressing the primary predisposing conditions related to sexual offending (e.g. pedophilic, hebephilic, paraphilic rape and non-contact paraphilic disorders, hyper sexuality and personality factors). In addition, special subgroups of sexual offenders (females, youth and the intellectually disable) are considered. Both broad and specific perspectives on the assessment of sexual offenders are provided. Overviews are offered of clinical and forensic evaluations of such offenders and the utility of structured psychological assessment. A novel conceptual model of risk assessment is proposed. More specifically, each of the primary approaches or instruments related to risk assessment of sexual offending are addressed: the Static risk assessment measures, the Sex Offender Risk Appraisal Guide, structured professional judgment, and the varied measures of dynamic or criminogenic needs assessment. Finally, multiple aspects of management of sexual offenders are discussed including models of psychosocial treatment, the question of the effectiveness of such treatment, biological interventions, civil commitment, circles of support, and the containment approach to community management. Chapters are authored by both prominent experts and experienced professionals for a breadth of perspective.Among the topics covered: Pedophilic, Hebephilic, Rape Paraphilic Disorders and the variety of Non Contact sexual offending conditionsPersonality, related conditions, & their association with sexual offending: motivators and disinhibition in context.Disorders of hyper sexuality.Assessments of sexual offenders, including the role of psychological testing, clinical & interview approaches, as well as forensic evaluationsConceptual models of risk assessment & discussion of specific static, dynamic & structured clinical risk assessment approachesModels of & reviews of treatment outcome with sexual offenders, including psychotherapy, psychopharmacology and castration, the containment approach, civil commitment & circles of supportOverview of public policy issues & an evidence-based perspective on sex offender registration and residential restrictions.This breadth of material in Sexual Offenders will help practitioners gain multiple levels of clinical insight as well as giving them up-to-date practical tools and techniques for working with this problematic class of individuals.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 912 pp. Englisch.

Buch. Zustand: Neu. Neuware -This volume aims to be a collection of essential protocols in iPS cell field. Induced Pluripotent Stem (iPS) Cells: Methods and Protocols guides readers through multiple facets of stem cell biology, lineage commitment and differentiation. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, Induced Pluripotent Stem (iPS) Cells: Methods and Protocols provides protocols that can be used by both experts and novices interested in stem cells.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 512 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -When developmental psychologists set forth the theory that the roots of adult psychopathology could be traced to childhood experience and behavior, the idea quickly took hold. Subsequently, as significant research in this area advanced during the past decade, more sophisticated theory, more accurate research methodologies, and improved replication of empirical findings have been the result.The Third Edition of the Handbook of Developmental Psychopathology incorporates these research advances throughout its comprehensive, up-to-date examination of this diverse and maturing field. Integrative state-of-the-art models document the complex interplay of risk and protective factors and other variables contributing to normal and pathological development. New and updated chapters describe current refinements in assessment methods and offer the latest research findings from neuroscience. In addition, the Third Edition provides readers with a detailed review across the spectrum of salient topics, from the effects of early deprivation to the impact of puberty.As the field continues to shift from traditional symptom-based concepts of pathology to a contemporary, dynamic paradigm, the Third Edition addresses such key topics as:Early Childhood disorders, including failure to thrive and attachment disorders.Aggression, ADHD, and other disruptive conditions.Developmental models of depression, anxiety, self-injury/suicide, and OCD.The autism spectrum and other chronic developmental disorders.Child maltreatment and trauma disorders.The Third Edition of the Handbook of Developmental Psychopathology is a discipline-defining, forward-looking resource for researchers, clinicians, scientist-practitioners, and graduate students in such fields as developmental psychology, psychiatry, social work, child and school psychology, educational psychology, and pediatrics.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 868 pp. Englisch.