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Taschenbuch. Zustand: Neu. Neuware -This monograph aims to provide a rigorous yet accessible presentation of some fundamental concepts used in modeling brain mechanics and give a glimpse of the insights and advances that have arisen as a result of the nascent interaction of the mathematical and neurosurgical sciences. It begins with some historical perspective and a brief synopsis of the biomedical/biological manifestations of the clinical conditions/diseases considered. Each chapter proceeds with a discussion of the various mathematical models of the problems considered, starting with the simplest models and proceeding to more complex models where necessary. A detailed list of relevant references is provided at the end of each chapter.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 168 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -From the reviews:¿The first volume is devoted to ergodic theory and dynamical systems. It contains 19 papers divided into four groups ¿ . The reader will find a wealth of information and ideas that can still ignite inspiration and motivate students as well as senior researchers. The reader will also have a touch of Sinai¿s personality, his taste, enthusiasm, and optimism, which are just as invaluable as his mathematical results.¿ (Nikolai Chernov, Mathematical Reviews, Issue 2012 e)Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 512 pp. Englisch.

Buch. Zustand: Neu. Neuware -A large-scale system is composed of several interconnected subsystems. For such a system it is often desired to have some form of decentralization in the control structure, since it is typically not realistic to assume that all output measurements can be transmitted to every local control station. Problems of this kind can appear in electric power systems, communication networks, large space structures, robotic systems, economic systems, and traffic networks, to name only a few. Typical large-scale control systems have several local control stations which observe only local outputs and control only local inputs. All controllers are involved, however, in the control operation of the overall system. The focus of this book is on the efficient control of interconnected systems, and it presents systems analysis and controller synthesis techniques using a variety of methods. A systematic study of multi-input, multi-output systems is carried out and illustrative examples are given to clarify the ideas.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 184 pp. Englisch.

Buch. Zustand: Neu. Neuware -RNA molecules play key roles in all aspects of cellular life, but to do so efficiently, they must work in synergism with proteins. This book addresses how proteins and RNA interact to carry out biological functions such as protein synthesis, regulation of gene expression, genome defense, liquid phase separation and more.The topics addressed in this volume will appeal to researchers in biophysics, biochemistry and structural biology. The book is a useful resource for anybody interested in elucidating the molecular mechanisms and discrete properties of RNA-protein complexes. Included are reviews of key systems such as microRNA and CRISPR/Cas that exemplify how RNA and proteins work together to perform their biological function. Also covered are techniques ranging from single molecule fluorescence and force spectroscopy to crystallography, cryo-EM microscopy, and kinetic modeling.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 260 pp. Englisch.

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - RNA molecules play key roles in all aspects of cellular life, but to do so efficiently, they must work in synergism with proteins. This book addresses how proteins and RNA interact to carry out biological functions such as protein synthesis, regulation of gene expression, genome defense, liquid phase separation and more.The topics addressed in this volume will appeal to researchers in biophysics, biochemistry and structural biology. The book is a useful resource for anybody interested in elucidating the molecular mechanisms and discrete properties of RNA-protein complexes. Included are reviews of key systems such as microRNA and CRISPR/Cas that exemplify how RNA and proteins work together to perform their biological function. Also covered are techniques ranging from single molecule fluorescence and force spectroscopy to crystallography, cryo-EM microscopy, and kinetic modeling.

Buch. Zustand: Neu. Neuware -This third edition volume expands on the previous editions with an update on the latest techniques used for the detection, genotyping, and investigating pathogenesis of Staphylococcus aureus in vitro and in vivo. The methods covered in this book mostly focus on routine clinical diagnosis, surveillance, research, and practice for treatment of patients infected by multi-drug resistant S. aureus. The book also covers the epidemiology of MRSA, molecular typing approaches, clinical treatment of MRSA infections, and animal models of drug discovery. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 280 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -Modeling Uncertainty: An Examination of Stochastic Theory, Methods, and Applications, is a volume undertaken by the friends and colleagues of Sid Yakowitz in his honor. Fifty internationally known scholars have collectively contributed 30 papers on modeling uncertainty to this volume. Each of these papers was carefully reviewed and in the majority of cases the original submission was revised before being accepted for publication in the book. The papers cover a great variety of topics in probability, statistics, economics, stochastic optimization, control theory, regression analysis, simulation, stochastic programming, Markov decision process, application in the HIV context, and others. There are papers with a theoretical emphasis and others that focus on applications. A number of papers survey the work in a particular area and in a few papers the authors present their personal view of a topic. It is a book with a considerable number of expository articles, which are accessible to a nonexpert - a graduate student in mathematics, statistics, engineering, and economics departments, or just anyone with some mathematical background who is interested in a preliminary exposition of a particular topic. Many of the papers present the state of the art of a specific area or represent original contributions which advance the present state of knowledge. In sum, it is a book of considerable interest to a broad range of academic researchers and students of stochastic systems.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 800 pp. Englisch.

Buch. Zustand: Neu. Neuware -It is well established that certain strains of yeasts are suitable for transforming grape sugars into alcohol, while other yeast strains are not suitable for grape fermentations. Recent progress has clearly demonstrated that the sensory profile of a wine is characteristic of each vine cultivated, and the quality and technological characteristics of the final product varies considerably due to the strains which have performed and/or dominated the fermentation process. Because of their technological properties, wine yeast strains differ significantly in their fermentation performance and in their contribution to the final bouquet and quality of wine, such as useful enzymatic activities and production of secondary compounds related both to wine organoleptic quality and human health. The wine industry is greatly interested in wine yeast strains with a range of specialized properties, but as the expression of these properties differs with the type and style of wine to be made, the actualtrend is in the use of selected strains, which are more appropriate to optimize grape quality. Additionally, wine quality can be influenced by the potential growth and activity of undesirable yeast species, considered spoilage yeasts, which cause sluggish and stuck fermentation and detrimental taste and aroma in the wine.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 536 pp. Englisch.